Results 31 to 40 of about 316,824 (311)

Increased tumor-associated mast cells facilitate thyroid cancer progression by inhibiting CD8+ T cell function through galectin-9

open access: yesBrazilian Journal of Medical and Biological Research, 2023
As an important component of solid tumors, mast cells show specific phenotypes in various tumor microenvironments. However, the precise mechanism of mast cell accumulation and the phenotypic features of thyroid cancer (TC) remain largely unknown.
Yanli Hou   +5 more
doaj   +1 more source

Mast Cells in Psoriasis [PDF]

open access: yesDermatology, 1996
WOS: A1996UA53400030 PubMed: 8829514 …
Ozdamar, SO   +3 more
openaire   +3 more sources

Mast Cell Targeted Chimeric Toxin Can Be Developed as an Adjunctive Therapy in Colon Cancer Treatment

open access: yesToxins, 2016
The association of colitis with colorectal cancer has become increasingly clear with mast cells being identified as important inflammatory cells in the process.
Shan Wang   +7 more
doaj   +1 more source

Interleukin-33 and Mast Cells Bridge Innate and Adaptive Immunity: From the Allergologist’s Perspective [PDF]

open access: yesInternational Neurourology Journal, 2015
Interleukin (IL) 33, a member of the IL-1 superfamily, is an “alarmin” protein and is secreted in its active form from damaged cells undergoing necrotic cell death. Mast cells are one of the main effector cell types in allergic disorders.
Tae Young Jang, Young Hyo Kim
doaj   +1 more source

Isolation and Culture of Peritoneal Cell-derived Mast Cells

open access: yesBio-Protocol, 2014
The generation of mast cells for in vitro studies comes from a variety of sources including mast cell lines (MC/9) (McCurdy et al., 2001), bone marrow-derived mast cells (BMMCs) (Supajatura et al., 2001), skin-derived mast cells (FSMCs) (Matsushima et al.
Krisztina Vukman   +3 more
doaj   +1 more source

Mast Cells and Neuroinflammation [PDF]

open access: yesMedical Science Monitor Basic Research, 2014
It has been determined that there is extensive communication between the immune system and the central nervous system (CNS). Proinflammatory cytokines play a key role in this communication. There is an emerging realization that glia and microglia, in particular, (which are the brain's resident macrophages), are an important source of inflammatory ...
Hongquan Dong, Yanning Qian, Xiang Zhang
openaire   +3 more sources

Isolation and Culture of Bone Marrow-derived Mast Cells

open access: yesBio-Protocol, 2014
The generation of mast cells for in vitro studies comes from a variety of sources including mast cell lines (MC/9) (McCurdy et al., 2001), bone marrow-derived mast cells (BMMCs) (Supajatura et al., 2001), skin-derived mast cells (FSMCs) (Matsushima et al.
Krisztina Vukman   +3 more
doaj   +1 more source

Mast Cells and Skin and Breast Cancers: A Complicated and Microenvironment-Dependent Role

open access: yesCells, 2021
Mast cells are important sentinel cells in host defense against infection and major effector cells in allergic disease. The role of these cells in cancer settings has been widely debated.
Mark R. Hanes   +2 more
doaj   +1 more source

Increased intratumoral mast cells foster immune suppression and gastric cancer progression through TNF-α-PD-L1 pathway

open access: yesJournal for ImmunoTherapy of Cancer, 2019
Background Mast cells are prominent components of solid tumors and exhibit distinct phenotypes in different tumor microenvironments. However, the nature, regulation, function, and clinical relevance of mast cells in human gastric cancer (GC) are ...
Yipin Lv   +18 more
doaj   +1 more source

Systemic mastocytosis with associated myeloproliferative disease and precursor B lymphoblastic leukaemia with t(13;13)(q12;q22) involving FLT3. [PDF]

open access: yes, 2008
Systemic mastocytoses represent neoplastic proliferations of mast cells. In about 20% of cases systemic mastocytoses are accompanied by clonal haematopoietic non-mast cell-lineage disorders, most commonly myeloid neoplasms.
Dirnhofer, S.   +7 more
core   +1 more source

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