Results 31 to 40 of about 11,909 (199)

Review papers The role of KIT gene mutations in pathogenesis of pediatric mastocytosis

Przegląd Dermatologiczny, 2015
Mastocytosis is characterized by excessive proliferation and accumulation of mast cells in skin and/or other organs. Two forms of the disease, cutaneous and systemic mastocytosis, differ significantly in symptomatology and clinical course.
Joanna Dawicka, Magdalena Lange, Bartosz Wasąg, Bogusław Nedoszytko, Aleksandra Wilkowska, Roman Nowicki   +5 more
doaj   +1 more source

Mastocytosis in the Skin: Disease Heterogeneity among Children and Adults

Acta Dermato-Venereologica, 2023
is missing (Short communication)
Christos Fokoloros, Paraskevi Xepapadaki, Evangelia `Papadavid, Alexandros Katoulis, Vasilliki Pappa, Sotirios Papageorgiou, Nikolaos G. Papadopoulos, Michael Makris   +7 more
doaj   +1 more source

Expanding the Immunologic and Neuronal Landscape of IgE-Mediated Anaphylaxis. [PDF]

Immunol Rev
ABSTRACT Anaphylaxis is a life‐threatening immunoglobulin E (IgE)‐mediated type I hypersensitivity reaction with rising prevalence and burden. It involves mast cell degranulation upon cross‐linking of antigen on mast cell‐bound IgE. Mechanisms of IgE‐mediated anaphylaxis remain incompletely understood, particularly the induction of systemic symptoms ...
Biswas R, Fried JM, Curotto de Lafaille MA.   +2 more
europepmc   +2 more sources

Human Skin/SCID Mouse Chimeras as an In Vivo Model for Human Cutaneous Mast Cell Hyperplasia [PDF]

, 1997
Human skin xenografted to mice with severe combined immunodeficiency syndrome (SCID) was evaluated to determine the integrity and fate of human dermal mast cells.
Melpo Christofidou-Solomidou, B. Jack Longley, Diana Whitaker-Menezes, Steven M. Albelda, George F. Murphy, Bosma, Caufield, Chomszynski, Christofidou-Solomidou, Christofidou-Solomidou, Costa, Dvorak, Galli, Gilliam, Grichnick, Gruber, Inemura, Juhasz, Juhasz, Juhasz, Kaminer, Karnovsky, Kessler, Lavker, Longley, Longley, Longley, Longley, Matsumura, Meininger, Mekori, Mirowski, Murphy, Petzelbauer, Schechter, Tsai, Valent, Walsh, Weidner, Weiss, Whitaker-Menezes, Yan, Yan   +42 more
core   +1 more source

Cutaneous types of mastocytosis in paediatry. Case report of maculopapular cutaneous mastocytosis in an infant

Клинический разбор в общей медицине, 2020
Mastocytosis is a heterogeneous group of neoplasms characterized by increased mast cells proliferation and accumulation in various organs and tissues. The paper introduces the newest mastocytosis classification and diagnosis principles.
Olga B. Tamrazova, Evgeniya A. Glukhova
doaj   +1 more source

PD-1 Regulates the Growth of Human Mastocytosis Cells

Allergology International, 2013
Background: Programmed death-1 (PD-1) is a marker for human neoplastic T cells. Here, we evaluated whether or not PD-1 was also a marker for human mastocytosis, and explored the role of PD-1 in human mastocytosis cells.
Tatsuki R. Kataoka, Masakazu Fujimoto, Koki Moriyoshi, Itsuko Koyanagi, Chiyuki Ueshima, Fumihiko Kono, Tatsuaki Tsuruyama, Yoshimichi Okayama, Chisei Ra, Hironori Haga   +9 more
doaj   +1 more source

A case report of primary cutaneous marginal zone B-cell lymphoma with mastocytosis

SAGE Open Medical Case Reports, 2021
A 53-year-old man presented with asymptomatic, dusky reddish nodules on his trunk, which had persisted for 7 years. Histological findings showed nodular to diffuse dermal infiltration of lymphocytes with irregular nuclei, eosinophils, plasma cells, and ...
Hyun Yi Lee, Joong Sun Lee, Dae Won Koo
doaj   +1 more source

Mastocytosis: a mutated KIT receptor induced myeloproliferative disorder [PDF]

, 2015
Although more than 90% systemic mastocytosis (SM) patients express gain of function mutations in the KIT receptor, recent next generation sequencing has revealed the presence of several additional genetic and epigenetic mutations in a subset of these ...
Chatterjee, Anindya, Ghosh, Joydeep, Kapur, Reuben   +2 more
core   +2 more sources

Pseudoxanthomatous mastocytosis in a 2-month female infant

Indian Journal of Dermatology, 2022
Mastocytosis is a rare disease characterized by infiltration of mast cells in various tissues like skin, bone marrow, liver, spleen, and gastrointestinal tract. Here, we present a case report of diffuse cutaneous mastocytosis (pseudoxanthomatous type) in
Tulika Rai, Atul Mohan, Neeraj Dhameja, Vandana Yadav   +3 more
doaj   +1 more source

Next Generation Sequencing of Genes With Epigenetic Alterations in Mastocytosis. [PDF]

Clin Transl Allergy
ABSTRACT Aim Mastocytosis is a neoplastic disease of the bone marrow associated with the risk of frequent and severe allergic reactions. However, the genetic predisposition is not fully understood, and the crucial element in pathogenesis is the presence of the oncogenic KIT p. D816 V gene mutation.
Górska A, van De Wetering T, Sobalska-Kwapis M, Nedoszytko B, Gutowska-Owsiak D, Niedoszytko M.   +5 more
europepmc   +2 more sources