Results 11 to 20 of about 77,151 (268)

Neuropsychiatric, cognitive and sexual impairment in mastocytosis patients

Orphanet Journal of Rare Diseases, 2021
Background Mastocytosis is a rare disease characterised by the accumulation and/or proliferation of abnormal mast cells (MCs) in one or several organs. It may present with a number of different symptoms that involve various organ systems.
Fatma Jendoubi, Maella Severino-Freire, Mathilde Negretto, Christophe Arbus, Carle Paul, Cristina Bulai Livideanu   +5 more
doaj   +1 more source

Pre-diagnostic and non-advanced systemic mastocytosis without cutaneous involvement have an increased risk of anaphylaxis. [PDF]

Front Allergy
Sangalli A, Pravettoni V, Sciumè M, Consonni D, Sartorio S, Montano N, Rivolta F.   +6 more
europepmc   +3 more sources

Mastocytosis [PDF]

Immunology and Allergy Clinics of North America, 2014
Mastocytosis is a disorder of abnormal mast cell proliferation, with clinical features that include flushing, pruritus, abdominal pain, diarrhea, hypotension, syncope, and musculoskeletal pain. These features are the result of mast cell mediator release and infiltration into target organs.
Melody C, Carter, Dean D, Metcalfe, Hirsh D, Komarow   +2 more
openaire   +2 more sources

Regulation of Reactive Oxygen Species and the Antioxidant Protein DJ-1 in Mastocytosis [PDF]

, 2016
Neoplastic accumulation of mast cells in systemic mastocytosis (SM) associates with activating mutations in the receptor tyrosine kinase KIT. Constitutive activation of tyrosine kinase oncogenes has been linked to imbalances in oxidant/antioxidant ...
Bai, Yun, Bandara, Geethani, Beaven, Michael A., Desai, Avanti, Kim, Do-Kyun, Komarow, Hirsh, Kulinski, Joseph M., Metcalfe, Dean D., Olivera, Ana, Prussin, Calman, Schwartz, Lawrence B.   +10 more
core   +12 more sources

Recalcitrant Cutaneous Mastocytosis Treated With Genetically Informed Targeted Therapy: A Case Report

International Journal of Dermatology and Venerology, 2023
Introduction:. Mastocytosis, a clonal proliferation of mast cells commonly involving the skin and bone marrow, has a varied clinical presentation ranging from cutaneous lesions to systemic disease.
Laura Gleason, Volkan Tekmen, Alexa Cohen, Safiyyah Bhatti, Burcu Beksac, Jisun Cha, Pierluigi Porcu, Neda Nikbakht   +7 more
doaj   +1 more source

Systemic Lymphadenopathic Mastocytosis with Eosinophilia

Diagnostics, 2022
Systemic mastocytosis is a neoplastic proliferation of mast cells that most frequently involves cutaneous sites. Mastocytosis involves various extracutaneous sites, but the lymph node is rare.
Soyoung Im, Jeong-A Kim, Gyeongsin Park, Uiju Cho   +3 more
doaj   +1 more source

How “benign” is cutaneous mastocytosis? A Danish registry-based matched cohort study

International Journal of Women's Dermatology, 2020
Background: There are limited estimates of the incidence rates (IRs) of mastocytosis, and only a few studies have addressed the long-term consequences of living with these diagnoses.
Line Kibsgaard, MD, PhD, Mette Deleuran, MD, Head of Department, Carsten Flohr, MD, Head of Department, Sinéad Langan, MD, Anne Braae Olesen, MD, PhD, Christian Vestergaard, MD, PhD   +5 more
doaj   +1 more source

Evaluating Melanoma Risk in Adult Mastocytosis: Potential Impact of Detection Bias - A Registry-based Study (Sweden). [PDF]

Acta Derm Venereol
Bergström A, Hägglund H, Berglund A, Nilsson G, Lambe M.   +4 more
europepmc   +3 more sources

SWATH-MS identification of CXCL7, LBP, TGFβ1 and PDGFRβ as novel biomarkers in human systemic mastocytosis

Scientific Reports, 2022
Mastocytosis is a rare myeloproliferative disease, characterised by accumulation of neoplastic mast cells in one or several organs. It presents as cutaneous or systemic.
R. L. J. Graham, A. A. McMullen, G. Moore, N. C. Dempsey-Hibbert, B. Myers, C. Graham   +5 more
doaj   +1 more source

PEDIATRIC MASTOCYTOSIS: AN UPDATE

Mediterranean Journal of Hematology and Infectious Diseases, 2021
Mastocytosis is a rare clonal disorder, characterized by excessive proliferation and accumulation of mast cells (MC) in various organs and tissues. Cutaneous mastocytosis (CM), the most common form in children, is defined when MC infiltration is limited ...
Fiorina Giona
doaj   +1 more source