Mastocytosis is a heterogeneous group of disorders in which mast cells exhibit clonal proliferation that infiltrates one or more organs. In cutaneous mastocytosis, the mast cells infiltrate the skin only, whereas systemic mastocytosis is diagnosed when ...
Awni Alshurafa +4 more
doaj +1 more source
Clinical Cases: Diagnostic Errors of Mastocytosis Cutaneous Forms in Children
Background. Mastocytosis refers to the group of rare diseases with pathological mast cells accumulation in tissues. Although diagnosis of cutaneous mastocytosis is not usually difficult for experienced physicians, misdiagnosis is possible.Clinical cases ...
Lianna K. Aslamazyan +4 more
doaj +1 more source
Fatal anaphylactic sting reaction in a patient with mastocytosis [PDF]
We report on a 33-year-old female patient with indolent systemic mastocytosis and urticaria pigmentosa who died of an anaphylactic reaction after a yellow jacket sting.
B. Przybilla +9 more
core +1 more source
Abstract Objectives The 2019 Workshop of the Society for Hematopathology/European Association for Haematopathology received and reviewed cases covering the spectrum of mastocytosis and related diseases, including morphologic mimics, focusing on recent updates and relevant findings for pathologists.
Alexandar, Tzankov +11 more
openaire +2 more sources
Targeted therapy for advanced forms of systemic mastocytosis in real clinical practice
Background. Mastocytosis is a heterogeneous group of diseases that are characterized by excessive proliferation and accumulation of clonal (neoplastic) mast cells in one or more organs.
D. I. Shikhbabaeva +8 more
doaj +1 more source
Immunological relationships during primary infection with Heligmosomoides polygyrus (Nematospiroides dubius): downregulation of specific cytokine secretion (IL-9 and IL-10) correlates with poor mastocytosis and chronic survival of adult worms [PDF]
Mice were infected either with Trichinella spiralis (day 0), Heligmosomoides polygyrus (day -14) or concurrently with both species and were killed in groups, together with naive control mice, on 2 occasions (day 8 and 15 post infection with T.
Behnke, Jerzy M. +5 more
core +2 more sources
KITD816V+ systemic mastocytosis associated with KITD816V+ acute erythroid leukaemia: first case report with molecular evidence for same progenitor cell derivation [PDF]
Toll-like receptor (TLR)-9 recognizes CpG motifs in microbial DNA. TLR9 signalling stimulates innate antimicrobial immunity and modulates adaptive immune responses including autoimmunity against chromatin, e.g., in systemic lupus erythematosus (SLE ...
H-P Horny +4 more
core +1 more source
Advanced systemic mastocytosis: from molecular and genetic progress to clinical practice
Systemic mastocytosis is a heterogeneous disease characterized by the accumulation of neoplastic mast cells in the bone marrow and other organ organs/tissues.
Celalettin Ustun +15 more
doaj +1 more source
Mastocytosis is a heterogeneous group of neoplasms characterized by increased mast cells proliferation and accumulation in various organs and tissues. The paper introduces the newest mastocytosis classification and diagnosis principles.
Olga B. Tamrazova, Evgeniya A. Glukhova
doaj +1 more source
Systemic mastocytosis with associated myeloproliferative disease and precursor B lymphoblastic leukaemia with t(13;13)(q12;q22) involving FLT3. [PDF]
Systemic mastocytoses represent neoplastic proliferations of mast cells. In about 20% of cases systemic mastocytoses are accompanied by clonal haematopoietic non-mast cell-lineage disorders, most commonly myeloid neoplasms.
Dirnhofer, S. +7 more
core +1 more source

