Results 21 to 30 of about 81,928 (305)
Review and Updates on Systemic Mastocytosis and Related Entities
Cancers, 2023 Simple Summary Mast cells are specialized immune cells that mediate allergic and anaphylactic reactions, among other immunologic functions. The accumulation of abnormal mast cells can give rise to various disorders that range in severity of symptoms and ...
Julie Y. Li +7 more
semanticscholar +1 more source
New Insights Into the Pathogenesis of Mastocytosis: Emerging Concepts in Diagnosis and Therapy.
Annual Review of Pathology, 2022 Mastocytosis is a heterogeneous group of neoplasms defined by a numerical increase and accumulation of clonal mast cells (MCs) in various organ systems. The disease may present as cutaneous mastocytosis or systemic mastocytosis (SM).
P. Valent +6 more
semanticscholar +1 more source
Systemic Lymphadenopathic Mastocytosis with Eosinophilia
Diagnostics, 2022 Systemic mastocytosis is a neoplastic proliferation of mast cells that most frequently involves cutaneous sites. Mastocytosis involves various extracutaneous sites, but the lymph node is rare.
Soyoung Im +3 more
doaj +1 more source
International Journal of Dermatology and Venerology, 2023 Introduction:. Mastocytosis, a clonal proliferation of mast cells commonly involving the skin and bone marrow, has a varied clinical presentation ranging from cutaneous lesions to systemic disease.
Laura Gleason +7 more
doaj +1 more source
Immunology and Allergy Clinics of North America, 2014 Mastocytosis is a disorder of abnormal mast cell proliferation, with clinical features that include flushing, pruritus, abdominal pain, diarrhea, hypotension, syncope, and musculoskeletal pain. These features are the result of mast cell mediator release and infiltration into target organs.
Melody C, Carter +2 more
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How “benign” is cutaneous mastocytosis? A Danish registry-based matched cohort study
International Journal of Women's Dermatology, 2020 Background: There are limited estimates of the incidence rates (IRs) of mastocytosis, and only a few studies have addressed the long-term consequences of living with these diagnoses.
Line Kibsgaard, MD, PhD +5 more
doaj +1 more source
Scientific Reports, 2022 Mastocytosis is a rare myeloproliferative disease, characterised by accumulation of neoplastic mast cells in one or several organs. It presents as cutaneous or systemic.
R. L. J. Graham +5 more
doaj +1 more source
Allergy. European Journal of Allergy and Clinical Immunology, 2022 Current diagnostic algorithms for systemic mastocytosis (SM) rely on the detection of KITD816V in blood to trigger subsequent bone marrow (BM) investigations.
Paula Navarro-Navarro +11 more
semanticscholar +1 more source
Case Reports in Oncology, 2023 Mastocytosis is a heterogeneous group of disorders in which mast cells exhibit clonal proliferation that infiltrates one or more organs. In cutaneous mastocytosis, the mast cells infiltrate the skin only, whereas systemic mastocytosis is diagnosed when ...
Awni Alshurafa +4 more
doaj +1 more source
Systemic Mastocytosis and Other Entities Involving Mast Cells: A Practical Review and Update
Cancers, 2022 Simple Summary In this article, we outline recent updates in systemic mastocytosis (SM) classification, including the bone marrow mastocytosis subtype; and discuss the mast cell leukemia subtype (acute or chronic), the rare variant of SM known as well ...
S. El Hussein +4 more
semanticscholar +1 more source