Results 61 to 70 of about 77,151 (268)

Metastases risk in thin cutaneous melanoma: Prognostic value of clinical-pathologic characteristics and mutation profile [PDF]

, 2018
Background: A high percentage of patients with thin melanoma (TM), defined as lesions with Breslow thickness ≤1 mm, presents excellent long-term survival, however, some patients develop metastases.
Calvieri, Stefano, Carbone, Anna, Donati, Pietro, Frascione, Pasquale, MARRAFFA, FEDERICA, Mattia, Cinzia Di, Ottini, Laura, Paolino, Giovanni, Richetta, Antonio G., Rizzolo, Piera, Silvestri, Valentina, Valentini, Virginia, Zelli, Veronica   +12 more
core   +1 more source

Sequence of Immunological Events During IgE‐Mediated Allergic Reactions to Food

Allergy, EarlyView.
ABSTRACT Food allergies (FA) represent a significant global health burden. Upon allergen re‐exposure, allergic patients exhibit a sequence of symptoms that vary in terms of affected organ systems, severity, time of onset and allergen reactivity thresholds.
N. A. Nagy, D. Schnoegl, V. Houghton, L. O'Mahony, A. F. Santos, E. F. Knol, A. Kuehn, T. Eiwegger   +7 more
wiley   +1 more source

Mastocitosis cutánea maculopapular infantil: reporte de un caso

Revista Médica Clínica Las Condes, 2019
Resumen: Objetivo: Reportar un caso de mastocitosis cutánea maculopapular de inicio en la infancia y realizar una revisión bibliográfica con énfasis en el diagnóstico, estudio, pronóstico y tratamiento.
Renatta de Grazia, Patricia Apt, Álvaro Ibarra, Ivo Sazunic   +3 more
doaj   +1 more source

Difficulties in diagnosis and management of mastocytosis in clinical practice and role of patients' associations [PDF]

Romanian Journal of Medical Practice, 2017
Mastocytosis is a heterogeneous group of disorders characterized by abnormal expansion and accumulation of mast cells in one or more organs. It is a rare disease, with uncertain prevalence in many countries. The diagnosis and management of rare diseases,
Polliana Mihaela LERU, Dumitru MATEI
doaj   +1 more source

Critical role of the mast cell/tryptase/PAR2 axis in anastrozole‐induced pain

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Anastrozole, an aromatase inhibitor, is used to treat postmenopausal women with hormone receptor‐positive breast cancer, but also induces musculoskeletal pain and can lead to therapeutic regimen suspension. Aromatase inhibitors promote the release of pro‐inflammatory substances from sensitised nerve fibres, which might ...
Maria Fernanda Pessano Fialho, Raquel Tonello, Evelyne Silva Brum, Gabriela Becker, Nigel W. Bunnett, Sara Marchesan Oliveira   +5 more
wiley   +1 more source

Case-control cohort study of patients' perceptions of disability in mastocytosis. [PDF]

PLoS ONE, 2008
BackgroundIndolent forms of mastocytosis account for more than 90% of all cases, but the types and type and severity of symptoms and their impact on the quality of life have not been well studied.
Olivier Hermine, Olivier Lortholary, Phillip S Leventhal, Adeline Catteau, Frédérique Soppelsa, Cedric Baude, Annick Cohen-Akenine, Fabienne Palmérini, Katia Hanssens, Ying Yang, Hagay Sobol, Sylvie Fraytag, David Ghez, Felipe Suarez, Stéphane Barete, Philippe Casassus, Beatrice Sans, Michel Arock, Jean Pierre Kinet, Patrice Dubreuil, Alain Moussy   +20 more
doaj   +1 more source

An adolescent girl with signs and symptoms of anaphylaxis and negative immunologic workup: a case report. [PDF]

, 2020
BackgroundThe increasing incidence of allergies and allergic reactions among children and adults has become a major public health concern. The etiology of allergic reactions can often be confirmed based on a detailed history and supportive testing ...
Bauer, Maureen, Frank, Guido KW, Green, Sarah, Hicks, Allison, Hilsendager, Chelsea   +4 more
core  

Human Skin/SCID Mouse Chimeras as an In Vivo Model for Human Cutaneous Mast Cell Hyperplasia [PDF]

, 1997
Human skin xenografted to mice with severe combined immunodeficiency syndrome (SCID) was evaluated to determine the integrity and fate of human dermal mast cells.
Melpo Christofidou-Solomidou, B. Jack Longley, Diana Whitaker-Menezes, Steven M. Albelda, George F. Murphy, Bosma, Caufield, Chomszynski, Christofidou-Solomidou, Christofidou-Solomidou, Costa, Dvorak, Galli, Gilliam, Grichnick, Gruber, Inemura, Juhasz, Juhasz, Juhasz, Kaminer, Karnovsky, Kessler, Lavker, Longley, Longley, Longley, Longley, Matsumura, Meininger, Mekori, Mirowski, Murphy, Petzelbauer, Schechter, Tsai, Valent, Walsh, Weidner, Weiss, Whitaker-Menezes, Yan, Yan   +42 more
core   +1 more source

Markedly Increased Diamine Oxidase During Acute Anaphylaxis Is Associated With an Underlying Clonal Mast Cell Disorder

Clinical &Experimental Allergy, EarlyView.
We provide the first evidence that pronounced release of DAO during anaphylaxis is restricted to patients with clonal mast cell disorder. This finding offers possible functional support for the reported association between KIT p.D816V and anaphylaxis severity.
Matija Rijavec, Žan Kogovšek, Jezerka Inkret, Peter Kopač, Mitja Košnik, Peter Korošec   +5 more
wiley   +1 more source

Splenomegaly, elevated alkaline phosphatase and mutations in the SRSF2/ASXL1/RUNX1 gene panel are strong adverse prognostic markers in patients with systemic mastocytosis [PDF]

, 2016
We evaluated the impact of clinical and molecular characteristics on overall survival (OS) in 108 patients with indolent (n=41) and advanced SM (advSM, n=67).
Clemens, J., Cross, N.C.P., Fabarius, A., Hausmann, D., Henzler, T., Hofmann, W.-K., Horny, H.-P., Jawhar, M., Metzgeroth, G., Naumann, N., Reiter, A., Schoenberg, S.O., Schwaab, J., Sotlar, K., Valent, P.   +14 more
core   +1 more source