Early Life Stress Increases Metabolic Risk, HPA Axis Reactivity, and Depressive-Like Behavior When Combined with Postweaning Social Isolation in Rats. [PDF]
PLoS ONE, 2016 Early-life stress is associated with depression and metabolic abnormalities that increase the risk of cardiovascular disease and diabetes. Such associations could be due to increased glucocorticoid levels.
Javier Vargas +3 more
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Targeting the Stress System During Gestation: Is Early Handling a Protective Strategy for the Offspring? [PDF]
, 2020 The perinatal window is a critical developmental time when abnormal gestational stimuli may alter the development of the stress system that, in turn, influences behavioral and physiological responses in the newborns.
Brancato, Anna +3 more
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Epigenetic upregulation of corticotrophin-releasing hormone mediates postnatal maternal separation-induced memory deficiency. [PDF]
PLoS ONE, 2014 Accumulating evidences demonstrated that early postnatal maternal separation induced remarkable social and memory defects in the adult rodents. Early-life stress induced long-lasting functional adaptation of neuroendocrine hypothalamic-pituitary-adrenal ...
Aiyun Wang +6 more
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Examining the Factorial Structure of the Maternal Separation Anxiety Scale in a Portuguese Sample
Frontiers in Psychology, 2021 The increase in women’s labor market participation emphasizes the importance of understanding maternal separation anxiety, that is, the unpleasant maternal emotional state, due to the actual or anticipated short-term separation from the child. Drawing on
Maryse Guedes +4 more
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Maternal Separation Impairs Cocaine-Induced Behavioural Sensitization in Adolescent Mice. [PDF]
PLoS ONE, 2016 Adverse early-life conditions induce persistent disturbances that give rise to negative emotional states. Therefore, early life stress confers increased vulnerability to substance use disorders, mainly during adolescence as the brain is still developing.
Irene Gracia-Rubio +5 more
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IBRO Neuroscience Reports, 2022 Environmental stimuli in early life are recognized to affect brain development and behavior. Mother-pup interaction constitutes a determinant stimulus during this critical period.
Ada Sinani +5 more
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Frontiers in Behavioral Neuroscience, 2022 The methyl-CpG binding protein 2 gene (MECP2) encodes an epigenetic transcriptional regulator implicated in neuronal plasticity. Loss-of-function mutations in this gene are the primary cause of Rett syndrome and, to a lesser degree, of other ...
Jose Vicente Torres-Pérez +8 more
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Factors Contributing to Maternal-Child Separation in Port-Au-Prince, Haiti
Annals of Global Health, 2019 Background: The Haitian orphanage sector receives more than 70 million United States Dollars (USD) in foreign aid annually and continues grow; there are over 500 orphanages in Port-Au-Prince alone.
Jessica Ashley +3 more
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Separation anxiety in families with emerging adults [PDF]
, 2013 In several developmental theories separation anxiety has been identified as an important feature of close interpersonal relationships. Most often, separation anxiety has been examined in the context of mother-child dyads in infancy. Increasingly, however,
Beyers, Wim, Kins, Evie, Soenens, Bart
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Parental Psychological Control: Maternal, Adolescent, and Contextual Predictors
Frontiers in Psychology, 2021 Parental psychological control (PC) hinders the development of autonomy, identity formation, and the attainment of self-determination and individuation of adolescents. The aim of this study was to deepen the understanding of which conditions increase the
J. Carola Pérez +3 more
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