Results 11 to 20 of about 2,028,316 (397)

Brief and long maternal separation in C57Bl6J mice: behavioral consequences for the dam and the offspring [PDF]

open access: yesFrontiers in Behavioral Neuroscience, 2023
IntroductionAnimal models, especially rodents, have become instrumental to experimentally investigate the effects of an adverse post-natal environment on the developing brain.
Cynthia Rombaut   +3 more
doaj   +2 more sources

Effects of Maternal Separation and Subsequent Stress on Behaviors and Brain Monoamines in Rats [PDF]

open access: yesBrain Sciences, 2023
Childhood adversity can induce maladaptive behaviors and increase risk for affective disorders, post-traumatic stress disorder, personality disorders, and vulnerability to stress in adulthood.
Polina V. Mavrenkova   +5 more
doaj   +2 more sources

Neonatal Maternal Separation Impairs Prefrontal Cortical Myelination and Cognitive Functions in Rats Through Activation of Wnt Signaling [PDF]

open access: hybridCerebral Cortex, 2016
&NA; Adverse early‐life experience such as depriving the relationship between parents and children induces permanent phenotypic changes, and impairs the cognitive functions associated with the prefrontal cortex (PFC).
Youjun Yang   +9 more
openalex   +2 more sources

Resveratrol ameliorates maternal separation-induced anxiety- and depression-like behaviors and reduces Sirt1-NF-kB signaling-mediated neuroinflammation

open access: yesFrontiers in Behavioral Neuroscience, 2023
Maternal separation in early life has a detrimental effect on the physiological and biochemical functions of the brains of offspring and can lead to anxiety- and depression-like behaviors later in life.
Ruifen Wei   +8 more
semanticscholar   +1 more source

Ganoderma Lucidum Triterpenoids Improve Maternal Separation-Induced Anxiety- and Depression-like Behaviors in Mice by Mitigating Inflammation in the Periphery and Brain

open access: yesNutrients, 2022
Although early life stress (ELS) can increase susceptibility to adulthood psychiatric disorders and produce a greater inflammatory response in a stressful event, targeted preventive and therapeutic drugs still remain scarce.
Xue Mi   +8 more
semanticscholar   +1 more source

The effects of maternal separation on behaviours under social-housing environments in adult male C57BL/6 mice

open access: yesScientific Reports, 2021
Adverse experience in early life can affect the formation of neuronal circuits during postnatal development and exert long-lasting influences on neural functions that can lead to the development of a variety of psychiatric disorders including depression,
Nozomi Endo   +7 more
semanticscholar   +1 more source

Limonene through Attenuation of Neuroinflammation and Nitrite Level Exerts Antidepressant-Like Effect on Mouse Model of Maternal Separation Stress

open access: yesBehavioural Neurology, 2021
Methods Mice were randomly divided into experimental groups as follows: the control group received normal saline and MS groups received normal saline, limonene (10 and 20 mg/kg), L-NAME (10 mg/kg), L-arginine (L-arg) (75 mg/kg), limonene (10 mg/kg) plus ...
Z. Lorigooini   +5 more
semanticscholar   +1 more source

Early Life Stress Increases Metabolic Risk, HPA Axis Reactivity, and Depressive-Like Behavior When Combined with Postweaning Social Isolation in Rats. [PDF]

open access: yesPLoS ONE, 2016
Early-life stress is associated with depression and metabolic abnormalities that increase the risk of cardiovascular disease and diabetes. Such associations could be due to increased glucocorticoid levels.
Javier Vargas   +3 more
doaj   +1 more source

Epigenetic upregulation of corticotrophin-releasing hormone mediates postnatal maternal separation-induced memory deficiency. [PDF]

open access: yesPLoS ONE, 2014
Accumulating evidences demonstrated that early postnatal maternal separation induced remarkable social and memory defects in the adult rodents. Early-life stress induced long-lasting functional adaptation of neuroendocrine hypothalamic-pituitary-adrenal ...
Aiyun Wang   +6 more
doaj   +1 more source

Examining the Factorial Structure of the Maternal Separation Anxiety Scale in a Portuguese Sample

open access: yesFrontiers in Psychology, 2021
The increase in women’s labor market participation emphasizes the importance of understanding maternal separation anxiety, that is, the unpleasant maternal emotional state, due to the actual or anticipated short-term separation from the child. Drawing on
Maryse Guedes   +4 more
doaj   +1 more source

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