Results 41 to 50 of about 261,235 (310)

Insecure attachment during infancy predicts greater amygdala volumes in early adulthood [PDF]

, 2014
Background The quality of the early environment is hypothesized to be an influence on morphological development in key neural areas related to affective responding, but direct evidence to support this possibility is limited.
Ahnert, Ainsworth, Baare, Barros-Loscertales, Baur, Bowlby, Brain Development Cooperative Group, Caetano, Caldji, Campbell, Cassidy, Chen, Cox, Dedovic, Erp, Fearon, Fox, Free, Gerritsen, Groh, Gunnar, Halligan, Hertsgaard, Holmes, Huang, Huot, Kaufman, Ladd, Ladouceur, Luby, Lupien, Lupien, MacMaster, MacMillan, Main, McCrory, Meaney, Mehta, Morey, Moutsiana, Munn, Murray, Murray, Murray, Ono, Pannekoek, Qin, Raineki, Rao, Rao, Romanczuk-Seiferth, Rorden, Rosso, Smith, Smith, Spangler, Spitzer, Spitzer, Tottenham, Videbech, Whalen, Wolff, Woolrich   +62 more
core   +2 more sources

Maternal separation in rats induces neurobiological and behavioral changes on the maternal side [PDF]

Scientific Reports, 2020
AbstractThe time after parturition is a sensitive period for mothers where they are prone to develop psychopathological symptoms. Studies investigating dams after separation from their pups (maternal separation, MS) showed that MS induces alterations similar to postpartum depression.
Bölükbas, Ibrahim, Mundorf, Annakarina (Dr. rer. nat.), Freund, Nadja (Prof. Dr. rer. nat.)   +2 more
openaire   +4 more sources

Early Life Stress Influences Oxidative Stress Enzyme Activities in Liver, Heart, Kidney, Suprarenal Glands, and Pancreas in Male and Female Rat Pups

Antioxidants
Early life stress (ELS) is a risk factor for the development of chronic diseases resulting from functional alterations of organs in the cardiorespiratory and renal systems. This work studied the changes in oxidative stress enzyme activities (EAs) of SOD,
Bertha Fenton Navarro, Alexis Abraham Casimiro Aguayo, Yayr Luis Torres Gómez, Miguel Cervantes Alfaro, Luz Torner   +4 more
doaj   +1 more source

A proposal for a brief-term post-adoption intervention in the attachment-perspective. A single case study with a late-adopted child and his adoptive mother [PDF]

, 2016
A growing body of attachment literature has focused on bridging the gap between research and clinical applications, even in clinical work with adoptive families.
D'Onofrio, Ester, Guerriero, Viviana, Pace, CECILIA SERENA, Zavattini, Giulio Cesare   +3 more
core   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Maternal separation as early-life stress: Mechanisms of neuropsychiatric disorders and inspiration for neonatal care

Brain Research Bulletin
The establishment of positive early parent–infant relationships provide essential nourishment and social stimulation for newborns. During the early stages of postnatal brain development, events such as synaptogenesis, neuronal maturation and glial ...
Yuan Zhang, Shu Wang, Mingyan Hei
doaj   +1 more source

Effects of early maternal separation on the expression levels of hippocampal and prefrontal cortex genes and pathways in lactating piglets

Frontiers in Molecular Neuroscience, 2023
IntroductionIn actual production, due to increased litter size when raising pigs, the management of piglets by split-suckling leads to intermittent neonatal maternal separation (MS).
Sitong Zhou, Yue Yang, Zheng Cheng, Mengyao Wu, Qi Han, Wenzhong Zhao, Honggui Liu, Honggui Liu   +7 more
doaj   +1 more source

'And a sword will pierce your soul also’: reflections on the holy mother and the holy child [PDF]

, 2016
This article explores themes of maternal purification and the separation of mother and child through close attention to the presentation narratives in Luke 2.
Walton, Heather
core  

Maternal separation

, 2022
The postpartum period is a sensitive time where women are especially vulnerable to develop postpartum depression (PPD), with 10%–15% of women affected. This review investigates whether the maternal separation (MS) paradigm in rodents holds the potential to help to understand mothers suffering from PPD.
Mundorf, Annakarina (Dr. rer. nat.), Bölükbas, Ibrahim, Freund, Nadja (Prof. Dr. rer. nat.)   +2 more
openaire   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source