Results 121 to 130 of about 5,938 (234)

Single-cell analysis of matrisome-related genes in breast invasive carcinoma: new avenues for molecular subtyping and risk estimation

Frontiers in Immunology
Background The incidence of breast cancer remains high and severely affects human health. However, given the heterogeneity of tumor cells, identifying additional characteristics of breast cancer cells is essential for accurate treatment.
Lingzi Su, Zhe Wang, Mengcheng Cai, Qin Wang, Man Wang, Wenxiao Yang, Yabin Gong, Fanfu Fang, Ling Xu   +8 more
semanticscholar   +1 more source

The extracellular matrix component perlecan/HSPG2 regulates radioresistance in prostate cancer cells

Frontiers in Cell and Developmental Biology
Radiotherapy of prostate cancer (PC) can lead to the acquisition of radioresistance through molecular mechanisms that involve, in part, cell adhesion-mediated signaling.
Ivana Samaržija, Ivana Samaržija, Vasyl Lukiyanchuk, Marija Lončarić, Anja Rac-Justament, Nikolina Stojanović, Ielizaveta Gorodetska, Uğur Kahya, Uğur Kahya, Jonathan D. Humphries, Mahak Fatima, Martin J. Humphries, Ana Fröbe, Anna Dubrovska, Anna Dubrovska, Anna Dubrovska, Anna Dubrovska, Anna Dubrovska, Andreja Ambriović-Ristov   +18 more
doaj   +1 more source

Unsupervised Analysis Reveals the Involvement of Key Immune Response Genes and the Matrisome in Resistance to BRAF and MEK Inhibitors in Melanoma

Cancers
Simple Summary Drug resistance is still an imminent issue for melanoma patients even after the use of BRAFi/MEKi combination therapy in clinic. Tumor heterogeneity and heterogeneity in treatment responses make it difficult to find consensus genes and ...
F. Liu‐Smith, Jianjian Lin
semanticscholar   +1 more source

Supplementary Data from Cancer Cell–Derived Matrisome Proteins Promote Metastasis in Pancreatic Ductal Adenocarcinoma

, 2023
Chenxi Tian, Daniel Öhlund, Steffen Rickelt, Tommy Lidström, Ying Huang, Liang Hao, Renee T. Zhao, Oskar Franklin, Sangeeta N. Bhatia, David A. Tuveson, Richard O. Hynes   +10 more
openalex   +1 more source

RGTA® or ReGeneraTing Agents mimic heparan sulfate in regenerative medicine: from concept to curing patients [PDF]

, 2017
The importance of extracellular matrix (ECM) integrity in maintaining normal tissue function is highlighted by numerous pathologies and situations of acute and chronic injury associated with dysregulation or destruction of ECM components. Heparan sulfate
Barritault, D. (Denis), Baudouin, C. (Christophe), Desgranges, P. (Pascal), Gilbert-Sirieix, M. (Marie), Neck, J.W. (Han) van, Papy-Garcia, D. (Dulce), Rice, K.L. (Kim Lee), Saffar, J.-L. (Jean-Louis), Siñeriz, F. (Fernando), Zakine, G. (Gilbert)   +9 more
core   +2 more sources

Matrisome remodeling in the myocardium of hypertrophic cardiomyopathy; novel targets for molecular diagnostics

Frontiers in Cell and Developmental Biology
Hypertrophic cardiomyopathy (HCM) is an inherited cardiac disorder characterized by left ventricular thickening and extracellular matrix (ECM) remodeling, often manifested as increased interstitial fibrosis that impair muscle function.
Ayman M. Ibrahim, Ayman M. Ibrahim, Hasnaa A. Elfawy, Cesare M. Terracciano, Magdi Yacoub, Magdi Yacoub   +5 more
doaj   +1 more source

Matrisome analysis of intrahepatic cholangiocarcinoma unveils a peculiar cancer-associated extracellular matrix structure [PDF]

, 2019
Guido Carpino, Diletta Overi, Fabio Melandro, Alessio Grimaldi, Vincenzo Cardinale, Sabina Di Matteo, Gianluca Mennini, Massimo Rossi, Domenico Alvaro, Vincenzo Barnaba, Eugenio Gaudio, Carmine Mancone   +11 more
openalex   +1 more source

Targeted matrisome analysis identifies thrombospondin-2 and tenascin-C in aligned collagen stroma from invasive breast carcinoma

Scientific Reports, 2018
Increasing evidence demonstrates an important role for the extracellular matrix (ECM) in breast cancer progression. Collagen type I, a core constituent of the fibrous ECM, undergoes a significant set of changes that accompany tumor progression, termed ...
Lucas A. Tomko, Ryan C. Hill, Alexander Barrett, Joseph M. Szulczewski, Matthew W. Conklin, Kevin W. Eliceiri, Patricia J. Keely, Kirk C. Hansen, Suzanne M. Ponik   +8 more
doaj   +1 more source

Transcriptome Profiling Reveals Matrisome Alteration as a Key Feature of Ovarian Cancer Progression [PDF]

, 2019
Sumegha Mitra, Kartikeya Tiwari, Ram Podicheti, Taruni Pandhiri, Douglas B. Rusch, Andrea Bonetto, Chi Zhang, Anirban K. Mitra   +7 more
openalex   +1 more source

The alternative matrisome: Alternative splicing of ECM proteins in development, homeostasis and tumor progression

, 2022
Zeinab Rekad, Valerio Izzi, Rijuta Lamba, Delphine Ciais, Ellen Van Obberghen‐Schilling   +4 more
openalex   +2 more sources