Results 101 to 110 of about 7,283,251 (294)

Microstructure and nanoindentation behavior of Cu composites reinforced with graphene nanoplatelets by electroless co-deposition technique

open access: yesScientific Reports, 2017
A reduced graphene oxide/copper (RGO/Cu) composite was fabricated by a surfactant free, electroless co-deposition technique. The graphene oxide (GO) sheets were reduced and RGO homogeneous distributed into the copper matrix.
Qi Zhang   +6 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Low-Temperature Soft-Cover-Assisted Hydrolysis Deposition of Large-Scale TiO2 Layer for Efficient Perovskite Solar Modules

open access: yesNano-Micro Letters, 2018
Perovskite solar cells with TiO2 electron transport layers exhibit power conversion efficiency (PCE) as high as 22.7% in single cells. However, the preparation process of the TiO2 layer is adopted by an unscalable method or requires high-temperature ...
Jinjin He   +6 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Interactions between the discoidin domain receptor 1 and β1 integrin regulate attachment to collagen

open access: yesBiology Open, 2013
Summary Collagen degradation by phagocytosis is essential for physiological collagen turnover and connective tissue homeostasis. The rate limiting step of phagocytosis is the binding of specific adhesion receptors, which include the integrins and ...
Lisa A. Staudinger   +7 more
doaj   +1 more source

Kernel matrix regression

open access: yes, 2007
We address the problem of filling missing entries in a kernel Gram matrix, given a related full Gram matrix. We attack this problem from the viewpoint of regression, assuming that the two kernel matrices can be considered as explanatory variables and ...
Vert, Jean-Philippe   +1 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

The impact of coaxial gas technology on the morphology of powder by gas atomisation and the additive manufactured mechanical performance

open access: yesVirtual and Physical Prototyping
Metal powders are essential for additive manufacturing (AM), with their morphology significantly impacting the performance of AM components. Gas atomisation (GA) is a common method for producing metal powders due to its efficiency and cost-effectiveness.
Sheng Luo   +9 more
doaj   +1 more source

Matrix code

open access: yesProceedings of the 14th symposium on Principles and practice of declarative programming, 2012
Matrix Code gives imperative programming a mathematical semantics and heuristic power comparable in quality to functional and logic programming. A program in Matrix Code is developed incrementally from a specification in pre/post-condition form. The computations of a code matrix are characterized by powers of the matrix when it is interpreted as a ...
openaire   +2 more sources

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