Results 71 to 80 of about 81,093 (306)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Journal of Aeronautics and Space Technologies (JAST)

Havacılık ve Uzay Teknolojileri Dergisi, 2019
As the competition gets more and more fierce in today’s markets, companies have to have an effectively chosen strategy in order to acquire better place in the market in which they are active.
Tuncay Gürbüz
doaj  

Matrix analytic methods in stochastic models

, 1997
Based on the proceedings of the first International Conference on Matrix-Analytic Methods (MAM) in Stochastic Models held recently in Flint, Michigan, this timely resource presents a general working knowledge of MAM through carefully designed tutorial ...
Chakravarthy, Srinivas R. 1953-
core  

Matrix analytic methods with Markov decision processes for hydrological applications. [PDF]

, 2014
In general, a physical process is modelled in terms of how its state evolves over time. The main challenge of modelling is to describe this evolution without unnecessary computation or making unrealistic simplifying assumptions.
Fisher, Aiden James
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Improved Point Dipole Model for Subwavelength Resolution Scattering Near-Field Optical Microscopy (SNOM)

International Journal of Antennas and Propagation, 2020
High-resolution microscopy technique is of significant importance for studying nanomaterials. It is necessary to understand the near-field interaction between the probe and substrate materials in order to get the fine structure of the nanomaterial in the
Guizhen Lu, Ruiqi Zhao, Hongcheng Yin, Zhihe Xiao, Jing Zhang   +4 more
doaj   +1 more source

A matrix constructive method for the analytic-numerical solution of coupled partial differential systems [PDF]

, 1995
summary:In this paper we construct analytic-numerical solutions for initial-boundary value systems related to the equation $u_t-Au_{xx}-Bu=0$, where $B$ is an arbitrary square complex matrix and $A$ ia s matrix such that the real part of the eigenvalues ...
Navarro, Enrique, Jódar, Lucas, Ferrer, M. V.   +2 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Testing moderator hypotheses in meta-analytic structural equation modeling using subgroup analysis [PDF]

, 2018
Meta-analytic structural equation modeling (MASEM) is a statistical technique to pool correlation matrices and test structural equation models on the pooled correlation matrix.
Cheung, M.W.-L, Cheung, M.W.-L., Jak, S, Jak, S.; id_orcid, Suzanne Jak, Jak, S., Mike W.-L. Cheung   +6 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source