Results 71 to 80 of about 31,315,155 (203)

Induced sputum MMP-1, -3 & -8 concentrations during treatment of tuberculosis. [PDF]

, 2013
INTRODUCTION: Tuberculosis (TB) destroys lung tissues and this immunopathology is mediated in part by Matrix Metalloproteinases (MMPs). There are no data on the relationship between local tissue MMPs concentrations, anti-tuberculosis therapy and sputum ...
Jorge Coronel, Friedland, Jon S, Bernabe-Ortiz, A., Coronel, Jorge, Gotuzzo, E., Gotuzzo Eduardo, Antonio Bernabe-Ortiz, Moore, David AJ, Ugarte-Gil, C.A., Coronel Jorge, Elkington, P.T., Moore, D.A.J., Eduardo Gotuzzo, Coronel, J., Paul Elkington, Robert H Gilman, Moore David A. J., Friedland, J.S., Gilman, R., Elkington Paul, Ugarte-Gil, Cesar A, Bernabe-Ortiz Antonio, Gilman Robert H., Cesar A Ugarte-Gil, Friedland Jon S., Elkington, Paul, Jon S Friedland, Gotuzzo, Eduardo, David A J Moore, Ugarte-Gil Cesar A., Tezera, Liku B, Gilman, Robert H, Liku B Tezera, Tezera Liku B., Bernabe-Ortiz, Antonio   +34 more
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Interplay between matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 in acute asthma exacerbation and airway remodeling

Egyptian Journal of Chest Disease and Tuberculosis, 2012
Background: Airway inflammation and remodeling of extracellular matrix are important features of asthma. Matrix metalloproteinases (MMPs) are group of enzymes expressed in the airways with their inhibitor (tissue inhibitor of MMPs (TIMP) and they are the
Ghada Mahmoud Mohamed, Mohamed Nazmy Farres, Hala Mahmoud   +2 more
doaj   +1 more source

Tenascin-C fragments are endogenous inducers of cartilage matrix degradation [PDF]

, 2011
Cartilage destruction is a hallmark of osteoarthritis (OA) and is characterized by increased protease activity resulting in the degradation of critical extracellular matrix (ECM) proteins essential for maintaining cartilage integrity.
Hermansson, M, Saralili Dipa Robertson, Wait, R, Robertson, SD, Wait, Robin, Monika Hermansson, Jonathan Jones, Philip Mitchell, Mitchell, P, Sofat, N, Nidhi Sofat, Jones, J, Robin Wait   +12 more
core   +1 more source

Coordinated elevation of membrane type 1-matrix metalloproteinase and matrix metalloproteinase-2 expression in rat uterus during postpartum involution

Reproductive Biology and Endocrinology, 2006
Background The changes occurring in the rodent uterus after parturition can be used as a model of extensive tissue remodeling. As the uterus returns to its prepregnancy state, the involuting uterus undergoes a rapid reduction in size primarily due to the
Kanaya Mika, Goto Taeko, Kitajima Yoshimitu, Yamazaki Kiyohiro, Honnma Hiroyuki, Nagasawa Kunihiko, Chida Mitunobu, Endo Toshiaki, Manase Kengo, Hayashi Takuhiro, Mitaka Toshihiro, Saito Tsuyoshi   +11 more
doaj   +1 more source

Fractional Excretion of Survivin, Extracellular Matrix Metalloproteinase Inducer, and Matrix Metalloproteinase 7 in Children with Chronic Kidney Disease [PDF]

, 2016
Background: Epithelial–mesenchymal transition (EMT) is defined as a transformation of tubular epithelial cells into mesenchymal ones. These cells migrate through the extracellular matrix and change into active myofibroblasts, which are responsible for ...
Agnieszka Bargenda, Kinga Musiał, Danuta Zwolińska   +2 more
core  

The increased of MMP-9 and MMP-2 with the decreased of TIMP-1 on the uterosacral ligament after childbirth

The Pan African Medical Journal, 2018
INTRODUCTION: Pelvic floor dysfunction is one of the causes of morbidity that have very active role in the degradation of collagen and elastin through an intermediary changes in matrix metalloproteinases (MMP) and its regulation.
Rahajeng Rahajeng
doaj   +1 more source

The influence of dusty environment (Makka city broken mountains) on bronchial asthma

Egyptian Journal of Chest Disease and Tuberculosis, 2014
Background: In the Kingdom of Saudi Arabia, the prevalence of asthma was 12%, with vast regional variations ranging from less than 10% in Dammam to 23% in Hail. Makka city has a lot of mountains that under the process of breaking causes dusty environment.
Nagat Ali Mohamed, Ghada Al-Akad
doaj   +1 more source

Novel bi- and trifunctional inhibitors of tumor-associated proteolytic systems [PDF]

, 2003
Serine proteases, cysteine proteases, and matrix metalloproteinases (MMPs) are involved in cancer cell invasion and metastasis. Recently, a recombinant bifunctional inhibitor (chCysuPA(19-31)) directed against cysteine proteases and the urokinasetype ...
Sato, Sumito, Assfalg-Machleidt, Irmgard, Magdolen, Ulla, Schmitt, Manfred, Rettenberger, Peter, Magdolen, Viktor, Krol, Janna   +6 more
core   +1 more source

Intracellular activation and processing of human disintegrin and metalloproteinase 19 (hADAM19) [PDF]

, 2003
Kang T. Intracellular activation and processing of human disintegrin and metalloproteinase 19 (hADAM19). Bielefeld (Germany): Bielefeld University; 2003.Adamalysin 19 (a disintegrin and metalloproteinase 19, ADAM19, or meltrin [beta]) is a plasma ...
Kang, Tiebang
core  

High threshold of β1 integrin inhibition required to block collagen I-induced membrane type-1 matrix metalloproteinase (MT1-MMP) activation of matrix metalloproteinase 2 (MMP-2) [PDF]

, 2014
Background\ud \ud Matrix metalloproteinase-2 (MMP-2) is an endopeptidase that facilitates extracellular matrix remodeling and molecular regulation, and is implicated in tumor metastasis.
Borrirukwanit, K, Borrirukwanit, Kulrut, Tony Blick, Marc A Lafleur, Erik W Thompson, Blick, T, Thompson, Erik, Thompson, EW, Pavasant, Prasit, Blick, Tony, Pavasant, P, Kulrut Borrirukwanit, Prasit Pavasant, Lafleur, Marc, Lafleur, MA   +14 more
core   +2 more sources