Results 11 to 20 of about 73,669,415 (286)

Differential expression of matrix metalloproteinase-13 in association with invasion of breast cancer [PDF]

Contemporary Oncology, 2016
Matrix metalloproteinase-13 (MMP-13) has a potential role in tumour invasion and metastasis. However, its relevance to the prognosis of human breast cancer is poorly understood.
Manas Kotepui, Chuchard Punsawad, Chaowanee Chupeerach, Apiram Songsri, Lek Charoenkijkajorn, Songsak Petmitr   +5 more
doaj   +5 more sources

Matrix metalloproteinase-13 unlucky for the forming thrombus. [PDF]

Res Pract Thromb Haemost, 2018
Matrix metalloproteinases (MMPs) are calcium‐dependent zinc‐containing endoproteases involved in extracellular matrix and non‐matrix protein degradation.1 In the latest issue of Research and Practice in Thrombosis and Haemostasis, Howes and colleagues2 ...
Montague SJ, Gardiner EE.
europepmc   +6 more sources

Pivotal role of matrix metalloproteinase 13 in extracellular matrix turnover in idiopathic pulmonary fibrosis. [PDF]

PLoS ONE, 2013
Idiopathic pulmonary fibrosis (IPF) is a fatal disease characterized by excessive deposition of extracellular matrix (ECM).We investigated the regulation of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in lung fibrosis.MMP and TIMP ...
Takwi Nkyimbeng, Clemens Ruppert, Takayuki Shiomi, Bhola Dahal, György Lang, Werner Seeger, Yasunori Okada, Jeanine D'Armiento, Andreas Günther   +8 more
doaj   +5 more sources

Immunohistochemical analysis of matrix metalloproteinase-13 in human caries dentin

European Journal of Histochemistry, 2014
The immunoexpression profile of matrix metalloproteinase-13 was investigated for the first time in dentin of human caries and healthy teeth. Twelve permanent premolars (10 caries and 2 sound) were decalcified in ethylenediaminetetraacetic acid and ...
C. Loreto, C. Galanti, G. Musumeci, M. C. Rusu, R. Leonardi   +4 more
doaj   +4 more sources

Selective Imaging of Matrix Metalloproteinase-13 to Detect Extracellular Matrix Remodeling in Atherosclerotic Lesions

Molecular Imaging and Biology, 2021
Overexpression and activation of matrix metalloproteinase-13 (MMP-13) within atheroma increases susceptibility to plaque rupture, a major cause of severe cardiovascular complications. In comparison to pan-MMP targeting [18F]BR-351, we evaluated the potential for [18F]FMBP, a selective PET radiotracer for MMP-13, to detect extracellular matrix (ECM ...
Ariel Buchler, Maxime Munch, Gedaliah Farber, Xiaoling Zhao, Rami Al-Haddad, Eadan Farber, Benjamin H. Rotstein   +6 more
openaire   +4 more sources

Comparison of matrix metalloproteinase-13 and tissue inhibitor of metalloproteinase-1 levels and alveolar bone density in chronic periodontitis before and after scaling and root planning

Majalah Kedokteran Gigi Indonesia, 2022
Periodontitis is typically associated with disorders characterized by compromised tooth-supporting tissue. Damage to periodontal tissue is caused by an imbalance between matrix metalloproteinases and their inhibitors.
Aini Hariyani Nasution, Lidya Irani Nainggolan, Widianto Meydhyono   +2 more
doaj   +2 more sources

Matrix metalloproteinase-13 refines pathological staging of precancerous colorectal lesions. [PDF]

Oncotarget, 2016
An exact classification of precancerous stages of colorectal polyps might improve therapy and patients´ outcome. Here we investigate the association between grade of dysplasia and Matrix metalloproteinase-13 (MMP-13) expression in 137 biopsies from patients with cancerous and non-cancerous colorectal adenomas.
Wernicke AK, Churin Y, Sheridan D, Windhorst A, Tschuschner A, Gattenlöhner S, Roderfeld M, Roeb E.   +7 more
europepmc   +8 more sources

Regulation and Function of Matrix Metalloproteinase-13 in Cancer Progression and Metastasis. [PDF]

Cancers (Basel), 2022
Matrix metalloproteinase-13 (MMP-13) is a member of the Matrix metalloproteinases (MMPs) family of endopeptidases. MMP-13 is produced in low amounts and is well-regulated during normal physiological conditions. Its expression and secretion are, however, increased in various cancers, where it plays multiple roles in tumour progression and metastasis. As
Li S, Pritchard DM, Yu LG.
europepmc   +3 more sources

In silico Study of Some Natural Anthraquinones on Matrix Metalloproteinase Inhibition [PDF]

Research Journal of Pharmacognosy, 2021
Background and objectives: Matrix metalloproteinase-13 (MMP-13) is a proteolytic enzyme playing an important role in the activation of the MMP cascade, which seems to be vital in both bone metabolism and homeostasis.
Amir Taherkhani, Shirin Moradkhani, Athena Orangi, Alireza Jalalvand, Zahra Khamverdi*   +4 more
doaj   +1 more source

Correction: Interleukin-1 Receptor Antagonist Has a Novel Function in the Regulation of Matrix Metalloproteinase-13 Expression. [PDF]

PLoS One, 2020
Correction: Interleukin-1 Receptor Antagonist Has a Novel Function in the Regulation of Matrix Metalloproteinase-13 ...
Goto H, Ishihara Y, Kikuchi T, Izawa A, Ozeki N, Okabe E, Kamiya Y, Ozawa Y, Mizutani H, Yamamoto G, Mogi M, Nakata K, Maeda H, Noguchi T, Mitani A.   +14 more
europepmc   +2 more sources