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Matrix Metalloproteinase-9 [PDF]
encoded by the human MMP9 gene. This protein plays a role in collagen degradation, macrophage differentiation and cell migration.
L. Moreland
openaire +2 more sources
Pathophysiological Role of Chymase-Activated Matrix Metalloproteinase-9
Chymase present in mast cells can directly form matrix metalloproteinase (MMP)-9 from proMMP-9. Chymase-activated MMP-9 has been reportedly closely related to the pathogenesis of various diseases, and inflammation-related diseases in particular ...
Shinji Takai, Denan Jin
doaj +3 more sources
Osteopontin is proteolytically processed by matrix metalloproteinase 9 [PDF]
Osteopontin is robustly upregulated following myocardial infarction (MI), which suggests that it has an important role in post-MI remodeling of the left ventricle (LV). Osteopontin deletion results in increased LV dilation and worsened cardiac function.
Merry L, Lindsey +4 more
openaire +3 more sources
The role of MMP-2 and MMP-9 in the metastasis and development of hypopharyngeal carcinoma
Introduction: The role of matrix metalloproteinase-2 and 9 in the metastasis and development of hypopharyngeal carcinoma has not been clarified. Objectives: To observe the relationship between matrix metalloproteinase-2, matrix metalloproteinase-9 and ...
Zhe Song +5 more
doaj +1 more source
Novel Matrix Metalloproteinase-9 (MMP-9) Inhibitors in Cancer Treatment
Matrix metalloproteinases (MMPs) belong to a family of zinc-dependent proteolytic metalloenzymes. MMP-9, a member of the gelatinase B family, is characterized as one of the most intricate MMPs.
Z. A. Rashid, S. Bardaweel
semanticscholar +1 more source
Regulation of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 in Abdominal Aortic Aneurysm
Abdominal aortic aneurysm (AAA) is a degenerative disease characterized by destruction and progressive expansion of the abdominal aortic wall. An AAA is typically defined as an enlargement of the abdominal aorta with diameter ≥3 cm or ≥50% greater than ...
Shuo Wang +3 more
doaj +1 more source
Matrix Metalloproteinase-9 as an Important Contributor to the Pathophysiology of Depression
Matrix metalloproteinases (MMPs) are physiologically expressed in the central nervous system in neurons, astrocytes and microglia, and their aberrant elevation contributes to a number of diseases. Amongst the MMP members, MMP−9 has generated considerable
Hongmin Li +7 more
semanticscholar +1 more source
The relationship between metastasis and mmp-9 in sheep with pulmonary adenocarcinomas [PDF]
Th is study aimed to evaluate the role of Matrix Metalloproteinase-9 in the metastasis of ovine pulmonary adenocarcinoma cases by immunohistochemical methods.
Emin KARAKURT +5 more
doaj +1 more source
Immunohistochemical expression of matrix metalloproteinase -9 in invasive meningioma
Background: Meningioma is a common intracranial tumor arising from the meningothelial (arachnoid) cells. Meningiomas are divided into 15 histological subtypes and three grades, including benign (grade I), atypical (grade II) and anaplastic (grade III ...
Samar U. Hasan* +4 more
doaj +1 more source

