Protective Role of Matrix Metalloproteinase-2 in Allergic Bronchial Asthma
Frontiers in Immunology, 2019 Inflammation, reversible obstruction, and hyperresponsiveness of the airways are characteristic findings of bronchial asthma. Several evidence has demonstrated the involvement of matrix metalloproteinase-2 in allergic airway inflammation.
Yoshinori Takahashi +17 more
doaj +2 more sources
Role of Matrix Metalloproteinase-2 in Eosinophil-Mediated Airway Remodeling
Frontiers in Immunology, 2018 Airway remodeling is responsible for the progressive decline of lung function in bronchial asthma. Matrix metalloproteinase-2 and fibroblast-to-myofibroblast transition are involved in tissue remodeling.
Yu Kuwabara +10 more
doaj +2 more sources
Anacardic Acid Inhibits the Catalytic Activity of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 [PDF]
Molecular Pharmacology, 2012 Cashew nut shell liquid (CNSL) has been used in traditional medicine for the treatment of a wide variety of pathophysiological conditions. To further define the mechanism of CNSL action, we investigated the effect of cashew nut shell extract (CNSE) on two matrix metalloproteinases, MMP-2/gelatinase A and MMP-9/gelatinase B, which are known to have ...
Athira, Omanakuttan +10 more
semanticscholar +6 more sources
Amelioration of Pulmonary Fibrosis by Matrix Metalloproteinase-2 Overexpression. [PDF]
Int J Mol Sci, 2023 Idiopathic pulmonary fibrosis is a progressive and fatal disease with a poor prognosis. Matrix metalloproteinase-2 is involved in the pathogenesis of organ fibrosis. The role of matrix metalloproteinase-2 in lung fibrosis is unclear. This study evaluated
Inoue R +13 more
europepmc +2 more sources
Matrix Metalloproteinase 2 Measurement [PDF]
Definitions, 2020 The determination of the amount of matrix metalloproteinase 2 present in a sample.
openaire +2 more sources
The Complex Role of Matrix Metalloproteinase-2 (MMP-2) in Health and Disease. [PDF]
Int J Mol SciMatrix metalloproteinase-2 (MMP-2), a zinc-dependent enzyme, plays a critical role in the degradation and remodeling of the extracellular matrix (ECM). As a member of the gelatinase subgroup of matrix metalloproteinases, MMP-2 is involved in a variety of
Wolosowicz M, Prokopiuk S, Kaminski TW.
europepmc +2 more sources
Dimerization of Matrix Metalloproteinase-2 (MMP-2) [PDF]
Journal of Biological Chemistry, 2012 Bon-Hun Koo +3 more
openaire +2 more sources
Pyrone-based inhibitors of metalloproteinase types 2 and 3 may work as conformation-selective inhibitors. [PDF]
, 2011 Matrix metalloproteinases are zinc-containing enzymes capable of degrading all components of the extracellular matrix. Owing to their role in human disease, matrix metalloproteinase have been the subject of extensive study.
de Oliveira, César AF +2 more
core +1 more source
Metalloproteinases and their Inhibitors under the Course of Immunostimulation by CPG-ODN and Specific Antigen Inhalation in Equine Asthma [PDF]
, 2019 Objectives. Inhalation of immunostimulatory bacterial DNA segments (cytosine-phosphate-guanosine-oligodeoxynucleotides, CpG-ODN) normalizes clinical and cytologic parameters in severe equine asthma.
Barton, Ann Kristin +5 more
core +1 more source
Biomedicines, 2023 Introduction: Urinary bladder cancer is a serious oncological problem that is the cause of many deaths worldwide. The processes of metastasis and origination of local tumor invasion depend on the extracellular matrix (ECM) degradation.
Jacek Kudelski +7 more
doaj +1 more source