Results 21 to 30 of about 700,477 (342)

Tight junction defects are seen in the buccal mucosa of patients receiving standard dose chemotherapy for cancer [PDF]

, 2016
Oral mucositis is one of the most common and debilitating side effects of chemotherapy treatment. Patients are often unable to eat and drink, which can lead to poor clinical outcomes and extensive resource utilisation.
Bowen, J., Gibson, R., Logan, R., Van Sebille, Y., Wardill, H.   +4 more
core   +1 more source

Matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in diagnosis of pleural effusion of malignant origin [PDF]

, 2016
OBJECTIVES: The aim of the present study was to evaluate the diagnostic accuracy of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in differentiating benign from malignant exudative pleural effusions.
D'Angelo, L., Di Carlo, A., Di Domenico, M., Feola, A., Fiorelli, A., Mazzella, A., Ricci, S., Santini, M.   +7 more
core   +1 more source

Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 Expression in Canine and Feline Meningioma [PDF]

Veterinary Pathology, 2009
Fifty-one meningiomas obtained from 28 dogs and 23 cats were selected for this study to investigate the immunohistochemical expression of matrix metalloproteinase (MMP)-2 and MMP-9 and to compare it to the reverse transcriptase subunit of human-telomerase, progesterone receptor expression, and the proliferative index of the tumors, expressed by Ki67 ...
M. T. Mandara, S. Pavone, MANDRIOLI, LUCIANA, BETTINI, GIULIANO, C. Falzone, M. Baroni   +5 more
openaire   +2 more sources

Bazedoxifene, a selective estrogen receptor modulator, reduces cerebral aneurysm rupture in Ovariectomized rats. [PDF]

, 2017
BackgroundEstrogen deficiency is thought to be responsible for the higher frequency of aneurysmal subarachnoid hemorrhage in post- than premenopausal women.
Hashimoto, Tomoki, Kitazato, Keiko T, Korai, Masaaki, Maekawa, Hidetsugu, Miyamoto, Takeshi, Nagahiro, Shinji, Satomi, Junichiro, Tada, Yoshiteru, Yagi, Kenji   +8 more
core   +1 more source

MMP-2 together with MMP-9 overexpression correlated with lymph node metastasis and poor prognosis in early gastric carcinoma

Tumor Biology, 2017
The aim of this study was to correlate matrix metalloproteinase-2 and matrix metalloproteinase-9 expression with the clinicopathological features and outcome of patients with early gastric cancer and to clinically elucidate more information on the role ...
Zhihua Yao, Tian Yuan, Haiying Wang, Shuna Yao, Yan Zhao, Ying Liu, Shuiling Jin, Junfeng Chu, Yuanlin Xu, Wenping Zhou, Shujun Yang, Yanyan Liu   +11 more
doaj   +1 more source

Cleavage of the leptin receptor by matrix metalloproteinase–2 promotes leptin resistance and obesity in mice

Science Translational Medicine, 2018
Matrix metalloproteinase–2 inhibition rescued leptin receptor expression in the hypothalamus and reduced fat accumulation in rodent models of obesity.
R. Mazor, D. Friedmann-Morvinski, T. Alsaigh, O. Kleifeld, E. Kistler, L. Rousso-Noori, Cheng Huang, Joyce B. Li, I. Verma, G. Schmid-Schönbein   +9 more
semanticscholar   +1 more source

Enhanced cardiac expression of two isoforms of matrix metalloproteinase-2 in experimental diabetes mellitus. [PDF]

, 2019
BackgroundDiabetic cardiomyopathy (DM CMP) is defined as cardiomyocyte damage and ventricular dysfunction directly associated with diabetes independent of concomitant coronary artery disease or hypertension.
Ahn, Jinhee, Bae, Sun Sik, Cha, Kwang Soo, Choi, Jung Hyun, Hong, Taek Jong, Kim, Sang Sik, Lee, Han Cheol, Lee, Hye Won, Lee, Min Young, Lee, Sun Ju, Lovett, David H, Oh, Jun-Hyok, Park, Jin-Sup, Park, Mi Wha, Shin, Nari, Song, Sang Heon   +15 more
core   +2 more sources

Attenuation of urokinase activity during experimental ischaemia protects the cerebral barrier from damage through regulation of matrix metalloproteinase-2 and NAD(P)H oxidase [PDF]

, 2014
Ischaemic injury impairs the integrity of the blood–brain barrier (BBB). In this study, we investigated the molecular causes of this defect with regard to the putative correlations among NAD(P)H oxidase, plasminogen–plasmin system components, and matrix ...
Ahn, Allen, Allen, Allen, Asahi, Asahi, Asahi, Baramova, Barr, Bayraktutan, Brouns, Cavdar, Chen, Chen, Cho, Chrissobolis, Ear, Eltzschig, Fuhrman, Hacke, Haworth, Hayashi, Hayashi, Higazi, Hong, Hosomi, Irigoyen, Kleikers, Kleinschnitz, Liu, Lucivero, Margaill, Nakase, Persidsky, Raat, Rosenberg, Selemidis, Shao, Shuaib, Suofu, Tahanian, Thornton, Tsuji, Walder, Wang, Wang   +45 more
core   +2 more sources

Expression and prognostic impact of matrix metalloproteinase-2 (MMP-2) in astrocytomas

PLoS ONE, 2017
Astrocytomas are the most frequent primary brain tumors in adults, and despite aggressive treatment patients often experience recurrence. Survival decreases with increasing tumor grade, and especially patients with grade IV glioblastoma have poor ...
R. K. Ramachandran, M. D. Sørensen, C. Aaberg-Jessen, S. K. Hermansen, B. Kristensen   +4 more
semanticscholar   +1 more source

Expression of matrix metalloproteinase-2 and 9 with their inhibitors, tissue inhibitors of metalloproteinase-1 and 2 in oral lichen planus

Journal of Orofacial Sciences, 2014
Objectives: The study aims to explore the expression of the matrix metalloproteinases (MMP-2, -9) and their inhibitors (tissue inhibitors of metalloproteinase [TIMP]-1, -2) as well as the correlation between them in the different morphological forms of ...
Natheer Hashim Al-Rawi, Thaer Kassim Al-Kassam, Ahlam Hameed Majeed   +2 more
doaj   +1 more source