Results 21 to 30 of about 295,802 (336)

The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) family [PDF]

open access: yes, 2015
The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) enzymes are secreted, multi-domain matrix-associated zinc metalloendopeptidases that have diverse roles in tissue morphogenesis and patho-physiological remodeling, in ...
A Colige   +145 more
core   +1 more source

Protease Inhibitor-Dependent Inhibition of Light-Induced Stomatal Opening

open access: yesFrontiers in Plant Science, 2021
Stomata in the epidermis of plants play essential roles in the regulation of photosynthesis and transpiration. Stomata open in response to blue light (BL) by phosphorylation-dependent activation of the plasma membrane (PM) H+-ATPase in guard cells. Under
Tenghua Wang   +10 more
doaj   +1 more source

Inhibitory antibodies designed for matrix metalloproteinase modulation [PDF]

open access: yes, 2019
The family of matrix metalloproteinases (MMPs) consists of a set of biological targets that are involved in a multitude of severe pathogenic events such as different forms of cancers or arthritis.
Fischer, Thomas, Riedl, Rainer
core   +1 more source

Extracellular matrix change in patients with various forms of atrial fibrillation

open access: yesJournal of Education, Health and Sport, 2017
Purpose: We studied the change in serum collagen markers in patients with various forms of atrial fibrillation (AF) Methods: Collagen type C-terminal propeptide (CTPK-I), C-terminal telopeptide of type I collagen (CTTK-I), matrix metalloproteinase I ...
A. V. Goryachiy   +5 more
doaj   +3 more sources

A Complete Expression Profile of Matrix-Degrading Metalloproteinases in Dupuytren’s Disease [PDF]

open access: yes, 2007
Dupuytren’s disease (DD) is a common fibrotic condition of the palmar fascia, leading to deposition of collagen-rich cords and finger contractions. The metzincin superfamily contains key enzymes in the turnover of collagen and other extracellular matrix ...
Adrian J. Chojnowski   +48 more
core   +1 more source

Selective function-blocking monoclonal human antibody highlights the important role of membrane type-1 matrix metalloproteinase (MT1-MMP) in metastasis. [PDF]

open access: yes, 2016
The invasion-promoting MT1-MMP is a cell surface-associated collagenase with a plethora of critical cellular functions. There is a consensus that MT1-MMP is a key protease in aberrant pericellular proteolysis in migrating cancer cells and, accordingly, a
Cieplak, Piotr   +5 more
core   +1 more source

Matrix metalloproteinases in liver injury, repair and fibrosis. [PDF]

open access: yes, 2015
The liver is a large highly vascularized organ with a central function in metabolic homeostasis, detoxification, and immunity. Due to its roles, the liver is frequently exposed to various insults which can cause cell death and hepatic dysfunction ...
Baber, John   +3 more
core   +1 more source

Perioceutics: Matrix metalloproteinase inhibitors as an adjunctive therapy for inflammatory periodontal disease

open access: yesJournal of Pharmacy and Bioallied Sciences, 2012
Matrix metalloproteinases (MMPs) form a group of more than 20 zinc-dependent enzymes that are crucial in the degradation of the main components in the extracellular matrix, and thereby play important roles in cell migration, wound healing, and tissue ...
Esther Nalini Honibald   +4 more
doaj   +1 more source

Do matrix metalloproteinase and cathepsin K inhibitors work synergistically to reduce dentin erosion? [PDF]

open access: yesJournal of Applied Oral Science, 2023
Objectives To evaluate the effects of matrix metalloproteinase (MMP) and cathepsin K (catK) inhibitors on resistance to dentin erosion. Methodology A total of 96 dentin specimens (3×3×2 mm) were prepared and randomly assigned into four groups (n=24 ...
Xiujiao LIN   +4 more
doaj   +1 more source

Matrix metalloproteinases at key junctions in the pathomechanism of stroke [PDF]

open access: yes, 2011
Matrix metalloproteinases play a crucial role in the remodelling of the extracellular matrix through direct degradation of its structural proteins and control of extracellular signaling.
Amento   +91 more
core   +1 more source

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