Results 11 to 20 of about 142,106 (266)

Plasma matrix metalloproteinases in neonates having surgery for congenital heart disease

open access: yesHeart International, 2009
During cardiopulmonary-bypass matrix-metalloproteinases released may contribute to ventricular dysfunction. This study was to determine plasma matrix-metalloproteinases in neonates after cardiopulmonary-bypass and their relation to post-operative course.
David B. Ross   +7 more
doaj   +1 more source

Matrix metalloproteinases in COVID-19: underlying significance

open access: yesBiotechnology & Biotechnological Equipment, 2023
The role of matrix metalloproteinases (MMPs) in pathogenesis and severity of coronavirus disease 2019 (COVID-19) is under extensive exploration. MMPs are a family of extracellular proteases involved in a variety of physiological and pathological ...
Usman Khalid   +2 more
doaj   +1 more source

Matrix metalloproteinases and their inhibitors

open access: yesФармакокинетика и Фармакодинамика, 2019
Metalloproteinase was discovered by Gross and Lapierre in 1962 for the first time. Since then, more than 20 enzymes of this family have been characterized, and their functions have been studied in detail.
O. S. Grigorkevich   +2 more
doaj   +1 more source

Matrix metalloproteinase-2 (MMP-2), MMP-9, tissue inhibitor of matrix metalloproteinases (TIMP-1) and transforming growth factor-β2 (TGF-β2) expression in eutopic endometrium of women with peritoneal endometriosis

open access: yesAnnals of Agricultural and Environmental Medicine, 2016
Introduction The prevalence of endometriosis among reproductive age women is 7–17%; however, these figures reach 20–50% in patients suffering from infertility. Matrix metalloproteinases (MMPs) activity is thought to be particularly essential in the early
Krzysztof Szymanowski   +3 more
doaj   +1 more source

Targeting matrix metalloproteinase MMP3 greatly enhances oncolytic virus mediated tumor therapy

open access: yesTranslational Oncology, 2021
In cancer, the extracellular matrix is extensively remodeled during chronic inflammation, thus affecting cell transcription, differentiation, migration and cell-cell interactions.
Minglong Liang   +8 more
doaj   +1 more source

Thermal stability of human matrix metalloproteinases

open access: yesHeliyon, 2020
Matrix metalloproteinases (MMP) are key players in the remodelling of the extracellular matrix under physiological and pathological conditions. Thermodynamic parameters of human recombinant metalloproteinases of the active (rMMP2, 3, 7, 8 and 9) and ...
Noemi Meraz-Cruz   +3 more
doaj   +1 more source

Changes in the extracellular matrix under the influence of anticoagulant therapy in patients with Q-myocardial infarction after thrombolysis

open access: yesZaporožskij Medicinskij Žurnal, 2014
Aim. Matrix metalloproteinases play a key role in adaptive postinfarction remodeling of the heart. In order to study the influence of anticoagulation therapy on the state of matrix metalloproteinases and their inhibitors, the incidence of post-infarction
S. M. Kyselov
doaj   +1 more source

Matrix Metalloproteinases in Health and Disease

open access: yesBiomolecules, 2020
Matrix metalloproteinases (MMPs) are members of an enzyme family and, under normal physiological conditions, are critical for maintaining tissue allostasis [...]
Raffaele Serra
doaj   +1 more source

MMP2 and MMP9 contribute to lung ischemia–reperfusion injury via promoting pyroptosis in mice

open access: yesBMC Pulmonary Medicine, 2022
Background Lung ischemia–reperfusion injury (LIRI) is a cause of poor prognosis in several lung diseases and after lung transplantation. In LIRI, matrix metalloproteinases and pyroptosis indicators change in parallel, both of them involvement of ...
Peng Zhou   +4 more
doaj   +1 more source

Matrix metalloproteinases in lung biology

open access: yesRespiratory Research, 2000
Despite much information on their catalytic properties and gene regulation, we actually know very little of what matrix metalloproteinases (MMPs) do in tissues.
Parks William C, Shapiro Steven D
doaj   +1 more source

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