Role of matrix Metalloproteinases in pituitary adenoma invasion
Though pituitary adenomas are benign tumors in most cases, a considerable fraction of PAs behave in a malignant-like manner and invade to the adjacent structures in sellar region, especially the cavernous sinuses.
Chengxian Yang, Xinjie Bao, Renzhi Wang
doaj +1 more source
Matrix metalloproteinases in liver injury, repair and fibrosis. [PDF]
The liver is a large highly vascularized organ with a central function in metabolic homeostasis, detoxification, and immunity. Due to its roles, the liver is frequently exposed to various insults which can cause cell death and hepatic dysfunction ...
Baber, John+3 more
core +1 more source
Plasma matrix metalloproteinases in neonates having surgery for congenital heart disease
During cardiopulmonary-bypass matrix-metalloproteinases released may contribute to ventricular dysfunction. This study was to determine plasma matrix-metalloproteinases in neonates after cardiopulmonary-bypass and their relation to post-operative course.
David B. Ross+7 more
doaj +1 more source
Protease-sensitive atelocollagen hydrogels promote healing in a diabetic wound model [PDF]
The design of exudate-managing wound dressings is an established route to accelerated healing, although such design remains a challenge from material and manufacturing standpoints. Aiming towards the clinical translation of knowledge gained in vitro with highly swollen rat tail collagen hydrogels, this study investigated the healing capability in a ...
arxiv +1 more source
Facial structure of matrix convex sets [PDF]
This article investigates the notions of exposed points and (exposed) faces in the matrix convex setting. Matrix exposed points in finite dimensions were first defined by Kriel in 2019. Here this notion is extended to matrix convex sets in infinite-dimensional vector spaces.
arxiv +1 more source
ASAP-SML: An Antibody Sequence Analysis Pipeline Using Statistical Testing and Machine Learning [PDF]
Antibodies are capable of potently and specifically binding individual antigens and, in some cases, disrupting their functions. The key challenge in generating antibody-based inhibitors is the lack of fundamental information relating sequences of antibodies to their unique properties as inhibitors.
arxiv +1 more source
Integrin α2β1 Expression Regulates Matrix Metalloproteinase-1-Dependent Bronchial Epithelial Repair in Pulmonary Tuberculosis. [PDF]
Pulmonary tuberculosis (TB) is caused by inhalation of Mycobacterium tuberculosis, which damages the bronchial epithelial barrier to establish local infection.
Akif A. Khawaja+8 more
core +6 more sources
Matrix metalloproteinases in COVID-19: underlying significance
The role of matrix metalloproteinases (MMPs) in pathogenesis and severity of coronavirus disease 2019 (COVID-19) is under extensive exploration. MMPs are a family of extracellular proteases involved in a variety of physiological and pathological ...
Usman Khalid+2 more
doaj +1 more source
A Hybrid Model of a Genetic Regulatory Network in Mammalian Sclera [PDF]
Myopia in human and animals is caused by the axial elongation of the eye and is closely linked to the thinning of the sclera which supports the eye tissue. This thinning has been correlated with the overproduction of matrix metalloproteinase (MMP-2), an enzyme that degrades the collagen structure of the sclera.
arxiv +1 more source
Regulation of mammary gland branching morphogenesis by the extracellular matrix and its remodeling enzymes. [PDF]
A considerable body of research indicates that mammary gland branching morphogenesis is dependent, in part, on the extracellular matrix (ECM), ECM-receptors, such as integrins and other ECM receptors, and ECM-degrading enzymes, including matrix ...
A Amour+139 more
core +2 more sources