Results 21 to 30 of about 142,106 (266)
Role of matrix metalloproteinase in the aneurismatic aortic disease
Monaldi Archives for Chest Disease, 2004 The aorta is involved in a large variety of diseases and the atherosclerotic aneurysms represent the most common type of these. Recent reports have attempted to clarify the mechanisms, that cause the formation and the progression of the atherosclerotic ...
Nicola Troisi +3 more
doaj +1 more source
Immunomodulatory role of metalloproteases in cancers: Current progress and future trends
Frontiers in Immunology, 2022 Metalloproteinases (MPs) is a large family of proteinases with metal ions in their active centers. According to the different domains metalloproteinases can be divided into a variety of subtypes mainly including Matrix Metalloproteinases (MMPs), A ...
Qi Wang +4 more
doaj +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018 Background Dilated cardiomyopathy (DCM) is a common cause of heart failure in adult and pediatric patients, but the underlying mechanism may vary in adults and children, with few studies conducted to date.
Sayantan Jana +7 more
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The possibilities of using the inhibitors of matrix metalloproteinases for keratoplasty
Трансплантология (Москва), 2023 Introduction. The review is devoted to the actual problem of treating patients with keratolysis. The role of matrix metalloproteinases in the pathogenesis of cornea and corneal graft melting is discussed as well as the practical experience of using ...
K. V. Sirotkina, E. V. Chentsova
doaj +1 more source
Biology, 2023 Matrix metalloproteinases (MMPs) are a group of proteolytic enzymes which are members of the zinc endopeptidase family. They have the ability to degrade extracellular matrix elements, allowing for the release of binding molecules and cell migration ...
Katarzyna Jadczyk-Sorek +4 more
doaj +1 more source
Anti-MMP-2 and MMP-9 activity of Salsola komarovii Iljin extract and its solvent fractions
Asian Pacific Journal of Tropical Biomedicine, 2020 Objective: To investigate matrix metalloproteinases (MMP)-2 and MMP-9 inhibitory effect of Salsola komarovii Iljin, an edible halophyte with health beneficial effects. Methods: Salsola komarovii crude extracts (SKI), and solvent (n-hexane, 85% aq.
Jung-Ha Kil +8 more
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Multifaceted role of Matrix Metalloproteinases (MMPs)
Frontiers in Molecular Biosciences, 2015 Matrix metalloproteinases (MMPs), a large family of calcium-dependent zinc-containing endopeptidases, are involved the tissue remodeling and degradation of the extracellular matrix.
Divya eSingh +3 more
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Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Are matrix metalloproteinases the missing link? [PDF]
Invertebrate Survival Journal, 2005 It is more and more evident that the matrix metalloproteinase (MMP) system is not a characteristicfeature of vertebrate animals only, as it can also be found in many invertebrate organisms. Thisendopeptidase family has been widely studied since its first
F Mannello, G Tonti, S Papa
doaj +2 more sources