Results 31 to 40 of about 331,204 (356)
Immunoexpression of matrix metalloproteinases MMP-1, MMP-2, MMP-9 and MMP-14 in extragenital endometriosis and eutopic endometrium [PDF]
The Moldovan Medical Journal, 2020 Background: Matrix metalloproteinases are proteolytic enzymes responsible for the disorder of extracellular matrix modeling in endometriosis and their involvement in the invasion process.
Eugeniu Cazacu +4 more
doaj +1 more source
Matrix metalloproteinases as new targets in Alzheimer's disease: Opportunities and Challenges [PDF]
Journal of Medicinal Chemistry, American Chemical Society, 2020, 2021 Although matrix metalloproteinases (MMPs) are implicated in the regulation of numerous physiological processes, evidences of their pathological roles have also been obtained in the last decades, making MMPs attractive therapeutic targets for several diseases.
arxiv
Matrix Metalloproteinases and Glaucoma Treatment. [PDF]
, 2020 Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes that degrade extracellular matrix (ECM) components such as collagen and have important roles in multiple biological processes, including development and tissue remodeling, both in ...
Dibas, Mohammed +3 more
core
Matrix metalloproteinases and their inhibitors
Фармакокинетика и Фармакодинамика, 2019 Metalloproteinase was discovered by Gross and Lapierre in 1962 for the first time. Since then, more than 20 enzymes of this family have been characterized, and their functions have been studied in detail.
O. S. Grigorkevich +2 more
doaj +1 more source
An injectable, self-healing and MMP-inhibiting hyaluronic acid gel via iron coordination [PDF]
, 2021 Regulating the activity of matrix metalloproteinases (MMPs) is a potential strategy for osteoarthritis (OA) therapy, although delivering this effect in a spatially and temporally localised fashion remains a challenge. Here, we report an injectable and self-healing hydrogel enabling factor-free MMP regulation and biomechanical competence in situ.
arxiv +1 more source
Annals of Agricultural and Environmental Medicine, 2016 Introduction The prevalence of endometriosis among reproductive age women is 7–17%; however, these figures reach 20–50% in patients suffering from infertility. Matrix metalloproteinases (MMPs) activity is thought to be particularly essential in the early
Krzysztof Szymanowski +3 more
doaj +1 more source
Matrix Metalloproteinases in Health and Disease
Biomolecules, 2020 Matrix metalloproteinases (MMPs) are members of an enzyme family and, under normal physiological conditions, are critical for maintaining tissue allostasis [...]
Raffaele Serra
doaj +1 more source
Chronic tendon pathology: molecular basis and therapeutic implications [PDF]
, 2005 Tendons are frequently affected by chronic pain or rupture. Many causative factors have been implicated in the pathology, which until relatively recently was under-researched and poorly understood.
Riley, GP
core +1 more source
Anti-MMP-2 and MMP-9 activity of Salsola komarovii Iljin extract and its solvent fractions
Asian Pacific Journal of Tropical Biomedicine, 2020 Objective: To investigate matrix metalloproteinases (MMP)-2 and MMP-9 inhibitory effect of Salsola komarovii Iljin, an edible halophyte with health beneficial effects. Methods: Salsola komarovii crude extracts (SKI), and solvent (n-hexane, 85% aq.
Jung-Ha Kil +8 more
doaj +1 more source
A Complete Expression Profile of Matrix-Degrading Metalloproteinases in Dupuytren’s Disease [PDF]
, 2007 Dupuytren’s disease (DD) is a common fibrotic condition of the palmar fascia, leading to deposition of collagen-rich cords and finger contractions. The metzincin superfamily contains key enzymes in the turnover of collagen and other extracellular matrix ...
Adrian J. Chojnowski +48 more
core +1 more source