Results 111 to 120 of about 185,337,068 (295)

Dietary Artificial Sweeteners: From Chemical Transformation in Food to Gut Microbial Processing

ChemFoodChem, EarlyView.
This review article unites classical and recent findings on the stability of artificial sweeteners in food. The focus is on ten sweeteners approved in the European Union: their chemical stability during processing and storage, individual degradation products, and their interactions with the intestinal microbiota.
Jürgen Lassak, Michael Hellwig
wiley   +1 more source

Clinical and genetic characteristics of maturity‐onset diabetes of the young type 13: A systematic review of the literature

Objective Maturity‐onset diabetes of the young type 13 (MODY13), a rare type of monogenic diabetes, is often misdiagnosed as type 1 or type 2 diabetes. To improve early diagnosis and precise treatment, we performed a systematic review and analysis of the
Mingwei Zhao, Xiaodong Hu, Yaning Chen
core   +1 more source

Maturity Onset Diabetes of the Young (MODY): French National Diagnosis and Care Protocol (PNDS, Protocole National de Diagnostic et de Soins)

Orphanet Journal of Rare Diseases
MODY (Maturity-Onset Diabetes of the Young) is characterized by autosomal dominant mode of inheritance, early onset of diabetes in the absence of autoimmunity directed to pancreatic β-cells, impaired insulin secretory capacity, however, maintained over ...
Danièle Dubois-Laforgue, Bruno Donadille, Cécile Ciangura , Chloé Amouyal, Jean-Baptiste Arnoux, Pascal Barat, Sabine Baron, Jacques Beltrand, Elise Bismuth, Clara Bouché, Jean-Claude Carel, Hélène Cavé, Sophie Christin-Maitre, Delphine Collin-Chavagnac, Christiane Damgé, Brigitte Delemer, Pierre Gourdy , Sophie Jacqueminet, Sonja Janmaat , Marc de Kerdanet, Laurence Kessler, Dominique Langin , Jean-Charles Nault, Jacky Nizard, Michel Polak , Rachel Reynaud, Cécile Saint-Martin, Igor Tauveron, René Valéro, Anne Vambergue, Marie-Christine Vantyghem, Camille Vatier, Marc Nicolino, Christine Bellanné-Chantelot, Corinne Vigouroux   +34 more
doaj   +1 more source

Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin‐Knockout and Supervillin‐Mutant Mice

Cytoskeleton, EarlyView.
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith, Lauren A. Tauer, Randall H. Friedline, Xiaodi Hu, Duy Tran, Yangyi E. Luo, Nacima Hadjout‐Rabi, Elisabeth R. Barton, Jason K. Kim, Elizabeth J. Luna   +9 more
wiley   +1 more source

Diabetic vascular disease and Maturity-onset diabetes of the young

, 2016
Aim: Vascular disease such as cardiovascular and cerebrovascular diseases, or retinopathy, nephropathy and neuropathy are common in diabetes.
Mafra, J.M., Bourbon, Mafalda, Gaspar, G.   +2 more
core  

Maturity onset diabetes of the young in pregnancy: diagnosis, management and prognosis of MODY in pregnancy

, 2017
Current management guidelines of diabetes within pregnancy do not differentiate between the underlying physiological dysfunctions that lead to dysglycaemia and provide generic guidance.
Dharmintra Pasupathy, Anita Banerjee, Reed, A., A. Reed, Rees, Kate, Pasupathy, Dharmintra, Kate Rees, Banerjee, Anita   +7 more
core   +1 more source

Artificial Intelligence in Ophthalmology: From Methodological Advances to Clinical Translation and Future Directions

Eye &ENT Research, EarlyView.
ABSTRACT Artificial intelligence (AI) is reshaping ophthalmology from task‐specific image analysis toward multimodal, longitudinal, and clinically integrated decision support. This narrative review summarizes the methodological evolution of ophthalmic AI, including traditional machine learning, task‐specific deep learning, self‐supervised learning ...
Yuxin Liu, Hanruo Liu
wiley   +1 more source

Missense glucokinase mutation in maturity-onset diabetes of the young and mutation screening in late-onset diabetes

, 1992
We describe a codon 299 mutation in the glucokinase gene in a British pedigree with maturity-onset diabetes of the young (MODY) resulting in a substitution of glycine to arginine.
Wainscote, J.S., Turner, R.C., J.S. Wainscoat, Lo, Y.M., P. Patel, Stoffel, M., Bell, J.I., Bell, G.I., A.M. Lucassen, G.I. Bell, R.C. Turner, Y-M.D. Lo, R. Page, Lucassen, A., M. Stoffel, Patel, P., A.T. Hattersley, J.I. Bell, Page, R., Hattersley, A.T.   +19 more
core   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle

ESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.
Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley   +1 more source