Results 101 to 110 of about 185,337,215 (295)

POLYMORPHISM IN GENES INVOLVED IN LIPID METABOLISM IN MODY PATIENTS

Атеросклероз, 2016
We have analyzed the lipid profile and polymorphism in the genes involved in lipid metabolism in patients with maturity onset diabetes of the young (MODY) in West Siberia, Russia.
M. I. Voevoda, E. V. Shakhtshneider, A. K. Ovsyannikova, O. D. Rymar, D. E. Ivanoshchuk, A. M. Kurilshikov, Yu. I. Ragino   +6 more
doaj  

Autoimmune Thyroid Diseases in Children and Adolescents with Maturity Onset Diabetes of the Young Type 2

, 2019
The relationship between type 1 diabetes mellitus (T1DM) and autoimmune thyropathies is well known and has been described in the literature. Based on present knowledge, the relationship between thyropathies and other forms of diabetes, such as monogenic ...
Regalbuto C., DOBBIANI, GIULIA, Calcaterra V., Larizza D., Montalbano C., Vinci F., De Silvestri A., Albertini R.   +7 more
core   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Diverse and rare candidate MODY gene variants were identified in one-fifth of a Bangladeshi cohort with nonobese, nonautoimmune youth-onset diabetes

Scientific Reports
The global distribution and frequency of maturity onset diabetes of the young (MODY) vary, necessitating investigation across diverse ethnic groups. This study aimed to investigate MODY gene variants and phenotypic characteristics among young Bangladeshi
Mashfiqul Hasan, Nusrat Sultana, Kishore Kumar Shil, Sayad Bin Abdus-Salam, Maksudur Rahman Nayem, Merina Oliver, Aswathi Padinjyarekara, Tamanna Golani, Mohammad Fazle Alam Rabbi, Md. Salimullah, Sharif Akhteruzzaman, Muhammad Abul Hasanat   +11 more
doaj   +1 more source

Experimental Models of Transcription Factor-Associated Maturity-Onset Diabetes of the Young [PDF]

, 2002
Six monogenic forms of maturity-onset diabetes of the young (MODY) have been identified to date. Except for MODY2 (glucokinase), all other MODY subtypes have been linked to transcription factors.
K. Hagenfeldt-Johansson, C. B. Wollheim, P. L. Herrera, Otten, L. A., Gauthier, B. R., H. Wang, Wang, Haiyan, Hagenfeldt-Johansson, Kerstin, L. A. Otten, B. R. Gauthier, Herrera, Pedro Luis, Wollheim, Claes   +11 more
core   +1 more source

A case series of necrotizing periodontal diseases in hospitalized patients: What hasn't been said yet?

Clinical Advances in Periodontics, EarlyView.
Abstract Background Necrotizing periodontal diseases (NPDs) are uncommon and severe inflammatory conditions characterized by tissue necrosis, painful ulceration, and rapid clinical progression, frequently associated with systemic immunosuppression. Limited data exist regarding their clinical presentation and management in hospital settings.
Osmaria Letthycia Carvalho Leal, Fernanda Bortolotto, Mariana Cristina Manoel, Gabriela Silveira de Araújo, Ana Carolina Fragoso Motta, Leandro Dorigan de Macedo, Lara Maria Alencar Ramos Innocentini, Joab Cabral Ramos, Isabel Schausltz Pereira Faustino   +8 more
wiley   +1 more source

Dietary Artificial Sweeteners: From Chemical Transformation in Food to Gut Microbial Processing

ChemFoodChem, EarlyView.
This review article unites classical and recent findings on the stability of artificial sweeteners in food. The focus is on ten sweeteners approved in the European Union: their chemical stability during processing and storage, individual degradation products, and their interactions with the intestinal microbiota.
Jürgen Lassak, Michael Hellwig
wiley   +1 more source

A Single Nucleotide Variant in HNF-1β is associated with Maturity-Onset Diabetes of the Young in a Large Chinese Family

Iranian Journal of Public Health, 2016
Background: Maturity-onset diabetes of the young (MODY) is a heterogeneous entity of monogenic disorders characterized by autosomal dominant inheritance.
Peng ZHOU, Ran WEI, Zhenkui GUO, Haining ZHU, Desmond CAMPBELL, Qi LI, Xiaoqun XU, Junfu WANG, Meng LUAN, Xing CHEN, Gang CHEN   +10 more
doaj  

Management and outcomes in pregnant patients with monogenic diabetes due to pathogenic variants in GCK and HNF1A genes

Frontiers in Endocrinology
BackgroundWhile treatment algorithms for the most common forms of monogenic diabetes (MD) are well established, managing affected pregnancies remains a clinical challenge.
Magdalena Szopa, Magdalena Szopa, Karolina Zawadzka, Michał Kania, Michał Kania, Przemysław Witek, Przemysław Witek, Katarzyna Cyganek, Katarzyna Cyganek   +8 more
doaj   +1 more source

Clinical and genetic characteristics of maturity‐onset diabetes of the young type 13: A systematic review of the literature

Objective Maturity‐onset diabetes of the young type 13 (MODY13), a rare type of monogenic diabetes, is often misdiagnosed as type 1 or type 2 diabetes. To improve early diagnosis and precise treatment, we performed a systematic review and analysis of the
Mingwei Zhao, Xiaodong Hu, Yaning Chen
core   +1 more source