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Maturity-onset diabetes of the young: a clinical history

Diabetic Medicine, 1998
A mild form of diabetes in young people was recognized in the pre-insulin era but was forgotten, probably because of Joslin's dictum that all young people with diabetes should have insulin as a safeguard against complications. After the introduction of sulphonylureas in the 1950s it was found, most notably by Fajans and Conn at the University of ...
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[Maturity-onset diabetes of the young].

Nederlands tijdschrift voor geneeskunde, 2016
Maturity-onset diabetes of the young (MODY) is the most common type of monogenic diabetes mellitus, estimated to account for approximately 1-4% of patients with diabetes. The predicted prevalence is, therefore, 20,000 patients in The Netherlands. Unfortunately less than 5% of these patients are confirmed by molecular genetic analysis.
Karin, van der Tuin   +5 more
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Diabetic Ketoacidosis in Patients with Maturity-Onset Diabetes of the Young

Experimental and Clinical Endocrinology & Diabetes
AbstractMaturity-onset diabetes of the young (MODY) is the most frequent monogenetic diabetes form. It is caused by mutations in genes important for the development and function of pancreatic beta-cells, resulting in impaired insulin secretion capacity.
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Maturity Onset Diabetes of the Young (Mody)

2001
Maturity Onset Diabetes of the Young (MODY) is a familial form of non-insulin dependent diabetes with autosomal dominant inheritance. Hyperglycemia in MODY subjects usually develops at childhood, adolescence or young adulthood, and is associated with primary insulin-secretion defects (1, 2).
Philippe Froguel, Gilberto Velho
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MODY: maturity-onset diabetes of the young

2000
Gli autori illustrano le caratteristiche del ...
IUGHETTI, Lorenzo   +2 more
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Maturity onset diabetes of the young--review.

Pediatric endocrinology reviews : PER, 2007
Maturity onset diabetes of the young (MODY) is characterized by a primary defect in insulin secretion and hyperglycemia, nonketotic disease, monogenic autosomal dominant mode of inheritance, age at onset less than 25 years, and lack of auto-antibodies. It accounts for 2-5% of all cases of non-type 1 diabetes.
Galia, Gat-Yablonski   +2 more
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Maturity Onset Diabetes of the Young

2009
Mark Oette   +194 more
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Maturity-onset diabetes of the young: an update.

Clinical laboratory, 2007
Maturity-onset diabetes of the young (MODY) is a dominantly inherited form of non-ketotic diabetes. It usually develops in childhood, adolescence or young adulthood. The disease is heterogenous regarding the genetic and clinical features. Until now, 6 causal genes have been identified.
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