Results 61 to 70 of about 5,453 (230)

Exploring Bioactive Metabolites From Fusarium falciforme and Aspergillus terreus Isolated From Protease‐Rich Fruits: Antifungal, Antitrypanosomal, and Enzymatic Inhibitory Activities

open access: yesChemistry &Biodiversity, Volume 22, Issue 11, November 2025.
Metabolites from fungi isolated from protease rich‐fruits displayed antifungal, antitrypanosomal and enzymatic inhibitory activities. ABSTRACT Fungal secondary metabolites display remarkable chemical diversity and biological potential, with applications in agriculture and pharmaceuticals. This study isolated and characterized bioactive metabolites from
Gabriela de Oliveira Almeida   +8 more
wiley   +1 more source

Evaluation of Antiviral Activity of Cyclic Ketones against Mayaro Virus

open access: yesViruses, 2021
Mayaro virus (MAYV) is a neglected arthropod-borne virus found in the Americas. MAYV infection results in Mayaro fever, a non-lethal debilitating disease characterized by a strong inflammatory response affecting the joints and muscles.
Luciana S. Fernandes   +7 more
doaj   +1 more source

Adaptive changes in alphavirus mRNA translation allowed colonization of vertebrate hosts [PDF]

open access: yes, 2012
Members of the Alphavirus genus are arboviruses that alternate replication in mosquitoes and vertebrate hosts. In vertebrate cells, the alphavirus resists the activation of antiviral RNA-activated protein kinase (PKR) by the presence of a prominent RNA
Ventoso, Iván
core   +2 more sources

Inhibition of Mayaro virus infection by bovine lactoferrin

open access: greenVirology, 2014
Mayaro virus (MAYV) is an arbovirus linked to several sporadic outbreaks of a highly debilitating febrile illness in many regions of South America. MAYV is on the verge of urbanization from the Amazon region and no effective antiviral intervention is available against human infections.
Carlos Alberto Marques de Carvalho   +5 more
openalex   +4 more sources

The Halogen Effect in [Cu(NHC)X] Compounds: A Case Study on the Anti‐Leishmania and Antiviral Activity of [Cu(IPr)X]

open access: yesChemistrySelect, Volume 10, Issue 31, August 15, 2025.
This study explores how changing halidesfrom Cl to Iinfluences ionic radius, antioxidant activity, and lipophilicity. These shifts significantly impact the biological potency of [Cu(IPr)X] compounds against Leishmania parasites and arboviruses. A strategic tweak in halogen identity paves the way for enhanced therapeutic performance in metal‐based drug ...
J. V. Fontes   +9 more
wiley   +1 more source

Mayaro Virus Induction of Oxidative Stress is Associated With Liver Pathology in a Non-Lethal Mouse Model

open access: yesScientific Reports, 2019
Mayaro virus (MAYV) causes Mayaro fever in humans, a self-limiting acute disease, with persistent arthralgia and arthritis. Although MAYV has a remerging potential, its pathogenic mechanisms remain unclear.
Camila Carla da Silva Caetano   +12 more
doaj   +1 more source

Genetic analysis of members of the species Oropouche virus and identification of a novel M segment sequence [PDF]

open access: yes, 2015
Oropouche virus (OROV) is a public health threat in South America, and in particular Northern Brazil, causing frequent outbreaks of febrile illness.
Azevedo, Raimunda S.S.   +8 more
core   +1 more source

Integrating Citizen Science and Remote Sensing Data to Identify Key Environmental Factors Influencing H5N1 Avian Influenza Virus Potential Spillover Risk in the Philippines

open access: yesGeoHealth, Volume 9, Issue 8, August 2025.
Abstract Highly pathogenic avian influenza (HPAI) virus presents a serious threat to poultry and public health worldwide, with transmission dynamics shaped by avian migration patterns and environmental conditions. Recent outbreaks in the Philippines highlight the urgent need for effective control measures.
John Oliver Sayseng, Ting‐Wu Chuang
wiley   +1 more source

Cryo-EM structure of the mature and infective Mayaro virus at 4.4 Å resolution reveals features of arthritogenic alphaviruses

open access: yesNature Communications, 2021
Mayaro virus (MAYV) is an emerging arbovirus in Central and South America that is transmitted by mosquitoes and causes arthritogenic disease. Here, the authors present the 4.4 Å resolution cryo-EM structure of MAYV and describe specific features of the ...
Helder V. Ribeiro-Filho   +13 more
doaj   +1 more source

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