Results 71 to 80 of about 5,453 (230)

Seroprevalence of Chikungunya and O'nyong‐nyong Viruses in Senegal, West Africa

Journal of Medical Virology, Volume 97, Issue 3, March 2025.
ABSTRACT Arthritogenic alphaviruses such as chikungunya (CHIKV) and o'nyong‐nyong (ONNV) viruses have shown capacity to cause widespread epidemics, with recurrent and sporadic outbreaks occurring throughout sub‐Saharan Africa. We analyzed the seroprevalence for CHIKV and ONNV in 470 non‐febrile subjects from three regions in Senegal (Sindia, 2018 ...
Prince Baffour Tonto, Mouhamad Sy, Ibrahima Mbaye Ndiaye, Mariama Toure, Amy Gaye, Mariama Aidara, Amadou Moctar Mbaye, Abdoulaye Kane Dia, Mamadou Alpha Diallo, Jules Francois Gomis, Mamadou Samb Yade, Younous Diedhiou, Baba Dieye, Khadim Diongue, Mame Cheikh Seck, Aida S. Badiane, Bobby Brooke Herrera, Daouda Ndiaye   +17 more
wiley   +1 more source

Virucidal activity of proanthocyanidin against Mayaro virus

Antiviral Research, 2019
Mayaro virus (MAYV) is a sublethal arbovirus transmitted by mosquitoes with possible installation of an urban cycle in the Americas. Its infection causes disabling arthralgia, and still, there is no vaccine or treatment to it. We recently investigated nearly 600 compounds by molecular docking and identified epicatechin as a potent antiviral against ...
Ariane Coelho, Ferraz, Thaís de Fátima Silva, Moraes, Waleska Stephanie da Cruz, Nizer, Michelli Dos, Santos, Antônio Helvécio, Tótola, Jaqueline Maria Siqueira, Ferreira, Sidney Augusto, Vieira-Filho, Vanessa Gonçalves, Rodrigues, Lucienir Pains, Duarte, Cintia Lopes, de Brito Magalhães, José Carlos, de Magalhães   +10 more
openaire   +2 more sources

Temperature-Mediated Effects on Mayaro Virus Vector Competency of Florida Aedes aegypti Mosquito Vectors [PDF]

, 2022
Abdullah A. Alomar, Barry W. Alto
openalex   +1 more source

Alphavirus nsP2: A Multifunctional Regulator of Viral Replication and Promising Target for Anti‐Alphavirus Therapies

Reviews in Medical Virology, Volume 35, Issue 2, March 2025.
ABSTRACT Alphaviruses are re‐emerging vector‐born pathogens that cause arthralgia or encephalitic diseases on a global scale. While a vaccine against chikungunya virus was recently approved, no vaccines currently exist for other alphaviruses, nor are there antiviral drugs for the treatment of alphavirus infections. Alphaviruses have positive‐strand RNA
Sainan Wang, Suresh Mahalingam, Andres Merits   +2 more
wiley   +1 more source

GloPID-R report on chikungunya, o'nyong-nyong and Mayaro virus, part 3: Epidemiological distribution of Mayaro virus

Antiviral Research, 2019
sponsorship: Global Research Collaboration for Infectious Disease ...
Pezzi, L., Rodriguez-Morales, A.J., Reusken, C.B., Ribeiro, G.S., LaBeaud, A.D., Lourenco-de-Oliveira, R., Brasil, P., Lecuit, M., Failloux, A.B., Gallian, P., Jaenisch, T., Simon, F., Siqueira, A.M., Rosa-Freitas, M.G., Rua, A. Vega, Weaver, S.C., Drexler, J.F., Vasilakis, N., de Lamballerie, X., Boyer, S., Busch, M., Diallo, M., Diamond, M.S., Drebot, M.A., Kohl, A., Neyts, J., Ng, L.FP., Rios, M., Sall, A., Simmons, G.   +29 more
openaire   +5 more sources

Frequency of resistance to methicillin and other antimicrobial agents among Staphylococcus aureus strains isolated from pigs and their human handlers in Trinidad [PDF]

, 2014
Background: Methicillin-resistant Staphylococcus aureus (MRSA) has emerged recently worldwide in production animals, particularly pigs and veal calves, which act as reservoirs for MRSA strains for human infection.
Adesiyun AA, Adesiyun AA, Akpaka PE, Ben Slama K, Boucher H, Chen R, Choi CS, Data P, De Neeling AJ, Del Giudice P, Dorobãt OM, Dressler AE, Faires MC, Felten A, Flayhart D, French GL, Fwity B, Garcia-Graells C, Glenn D, Gootz TD, Graveland H, Haenni M, Haque N, Hartmann FA, Holmes MA, Jarvis WR, Jensen SO, Kerwat K, Lewis HC, Magiorakos AP, Malhotra-Kumar S, Maree CL, Meemken D, Mine Y, Moodley A, Morris DO, Munckhof WJ, Nonhoff C, Perry JD, Piskin N, Pletinckx LJ, Porrero MC, Riesen A, Rijnders MIa, Rubin JL, Saxema S, Shrestha B, Smith TC, Tenhagen BA, Tiwari HK, Van Cleef BA, Weese JS, Wulf MW   +52 more
core   +1 more source

Two Birds With One Stone: RNA Virus Strategies to Manipulate G3BP1 and Other Stress Granule Components

WIREs RNA, Volume 16, Issue 2, March/April 2025.
Stress granules emerging during viral infection can play both pro‐ and antiviral roles. RNA viruses use various strategies to antagonize their formation, including the degradation, inhibition, or sequestration of G3BP1, a key stress granule protein. However, biochemical and structural insights into these mechanisms have been reported for only a handful
Moh Egy Rahman Firdaus, Eliana Dukhno, Rupali Kapoor, Piotr Gerlach   +3 more
wiley   +1 more source

Chikungunya Virus: Unveiling Its Global Impact (2002–2024)

Interdisciplinary Perspectives on Infectious Diseases, Volume 2025, Issue 1, 2025.
Chikungunya virus (CHIKV), an arbovirus transmitted by Aedes mosquitoes, has caused massive global epidemics, where it causes periodic outbreaks of febrile illness. In recent years, it has afflicted populations of Africa, South America, and Southeast Asia.
Rakhi Issrani, Hafiz Muhammad Zeeshan, Jawairia Javed, Faqeeha Javed, Abid Iqbal, Shahzad Ahmad, Muhammad Amber Fareed, Shazia Iqbal, Suraiya Saleem   +8 more
wiley   +1 more source

A Novel Self‐Amplifying mRNA with Decreased Cytotoxicity and Enhanced Protein Expression by Macrodomain Mutations

Advanced Science, Volume 11, Issue 43, November 20, 2024.
This research shows an example that reducing innate immunogenicity to increase payload protein expression of self‐amplifying RNA via a single mutation in the macrodomain. The mutant saRNA attenuates the activation of the double‐stranded RNA sensor as well as the downstream interferon response.
Yue Gong, Danni Yong, Gensheng Liu, Jiang Xu, Jun Ding, William Jia   +5 more
wiley   +1 more source

Deltas: New paradigms

The Depositional Record, Volume 10, Issue 5, Page 600-636, November 2024.
This paper discusses some new paradigms concerning the origin and significance of deltas and their deposits. It proposes a broader definition of deltas that takes into account the importance of sediment‐laden fluvial discharges in controlling deltaic sedimentation.
Carlos Zavala, Mariano Arcuri, Agustin Zorzano, Valentín Trobbiani, Antonela Torresi, Ainara Irastorza   +5 more
wiley   +1 more source