Results 81 to 90 of about 5,453 (230)

Genome signatures, self-organizing maps and higher order phylogenies: a parametric analysis [PDF]

open access: yes, 2007
Genome signatures are data vectors derived from the compositional statistics of DNA. The self-organizing map (SOM) is a neural network method for the conceptualisation of relationships within complex data, such as genome signatures.
Gatherer, Derek
core   +4 more sources

Experimental Transmission of Mayaro Virus by Aedes aegypti [PDF]

open access: yesThe American Society of Tropical Medicine and Hygiene, 2011
Outbreaks of Mayaro fever have been associated with a sylvatic cycle of Mayaro virus (MAYV) transmission in South America. To evaluate the potential for a common urban mosquito to transmit MAYV, laboratory vector competence studies were performed with Aedes aegypti from Iquitos, Peru. Oral infection in Ae.
Kanya C, Long   +6 more
openaire   +2 more sources

Obesity's Unexpected Influence: Reduced Alphavirus Transmission and Altered Immune Activation in the Vector

open access: yesJournal of Medical Virology, Volume 96, Issue 11, November 2024.
ABSTRACT Chikungunya virus (CHIKV) and Mayaro virus (MAYV) are emerging/re‐emerging alphaviruses transmitted by Aedes spp. mosquitoes and responsible for recent disease outbreaks in the Americas. The capacity of these viruses to cause epidemics is frequently associated with increased mosquito transmission, which in turn is governed by virus−host−vector
Pallavi Rai   +4 more
wiley   +1 more source

Emerging alphaviruses in the Americas: Chikungunya and Mayaro [PDF]

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2014
Chikungunya virus (CHIKV) and Mayaro virus (MAYV) are emergent arthropod-borne viruses that produce outbreaks of acute febrile illness with arthropathy. Despite their different continental origins, CHIKV and MAYV are closely related and are components of the Semliki Forest Complex of the Alphavirus (Togaviridae).
Figueiredo, Mario Luis Garcia de   +1 more
openaire   +5 more sources

Applications and advancements in animal models for antiviral research on mosquito‐borne arboviruses

open access: yesAnimal Models and Experimental Medicine, Volume 7, Issue 5, Page 673-684, October 2024.
Animal models are crucial in antiviral research on mosquito‐borne arboviruses, playing a role in understanding disease mechanisms, vaccine development, and toxicity testing. The use of animal models confronts hurdles related to ethical considerations and the successful translation of findings from animals to humans.
Megan Caifeng Tang   +3 more
wiley   +1 more source

Genomic and phenotypic characterization of the Oropouche virus strain implicated in the 2022–24 large‐scale outbreak in Brazil

open access: yesJournal of Medical Virology, Volume 96, Issue 10, October 2024.
Abstract The Orthobunyavirus oropoucheense species encompasses a group of arthropod‐borne zoonotic viruses transmitted by biting midges to animals including humans. Several large‐scale human outbreaks caused by the prototype member of this species, Oropouche virus (OROV) have been documented since the 1970s and were primarily confined to the Amazon ...
Elisa de A. N. Azevedo   +17 more
wiley   +1 more source

Alpha‐mannosidase‐2 modulates arbovirus infection in a pathogen‐ and Wolbachia‐specific manner in Aedes aegypti mosquitoes

open access: yesInsect Molecular Biology, Volume 33, Issue 4, Page 362-371, August 2024.
Mosquito genetic background can modulate Wolbachia pathogen‐blocking phenotypes. The alpha‐mannosidase‐2 gene has previously been identified as a potential candidate. αMan2 CRISPR KO mutagenesis suppresses dengue virus titres but increases Mayaro virus titres, in Wolbachia‐uninfected mosquitoes.
Nadya Urakova   +12 more
wiley   +1 more source

Quercetin and quercetin 3-O-glycosides from Bauhinia longifolia (Bong.) Steud. show anti-Mayaro virus activity

open access: yesParasites & Vectors, 2014
Background The arthropod-borne Mayaro virus (MAYV) causes ‘Mayaro fever’, a disease of medical significance, primarily affecting individuals in permanent contact with forested areas in tropical South America. Recently, MAYV has attracted attention due to
Alda E dos Santos   +7 more
doaj   +1 more source

An unidentified cluster of infection in the Peruvian Amazon region [PDF]

open access: yes, 2015
Introduction: Bartonella bacilliformis is the etiological agent of Carrion’s disease, which is a neglected disease linked to people in low-socioeconomic populations in Andean valleys. An outbreak of B.
Bustamante, Pershing   +7 more
core   +3 more sources

Research progress toward the influence of mosquito salivary proteins on the transmission of mosquito‐borne viruses

open access: yesInsect Science, Volume 31, Issue 3, Page 663-673, June 2024.
Mosquito salivary proteins (MSPs) bear multitudinous functions, embracing facilitating blood feeding and affecting the infection of mosquito‐borne viruses (MBVs) via directly interplaying with MBVs or tuning the homeostasis of host cells. In vivo, MSPs can modulate host's innate and adaptive immunity, which in turn impacts the native infection at the ...
Zhao‐Yang Wang   +3 more
wiley   +1 more source

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