Results 71 to 80 of about 4,380 (198)

Exploring Bioactive Metabolites From Fusarium falciforme and Aspergillus terreus Isolated From Protease‐Rich Fruits: Antifungal, Antitrypanosomal, and Enzymatic Inhibitory Activities

Chemistry &Biodiversity, Volume 22, Issue 11, November 2025.
Metabolites from fungi isolated from protease rich‐fruits displayed antifungal, antitrypanosomal and enzymatic inhibitory activities. ABSTRACT Fungal secondary metabolites display remarkable chemical diversity and biological potential, with applications in agriculture and pharmaceuticals. This study isolated and characterized bioactive metabolites from
Gabriela de Oliveira Almeida, Vitor de Souza Mazucato, Ludmilla Tonani, Marcia Regina von Zeska Kress, Gisele Barbosa, Renata Krogh, Adriano Defini Andricopulo, Leonardo Luiz Gomes Ferreira, Paulo Cezar Vieira   +8 more
wiley   +1 more source

The Halogen Effect in [Cu(NHC)X] Compounds: A Case Study on the Anti‐Leishmania and Antiviral Activity of [Cu(IPr)X]

ChemistrySelect, Volume 10, Issue 31, August 15, 2025.
This study explores how changing halidesfrom Cl to Iinfluences ionic radius, antioxidant activity, and lipophilicity. These shifts significantly impact the biological potency of [Cu(IPr)X] compounds against Leishmania parasites and arboviruses. A strategic tweak in halogen identity paves the way for enhanced therapeutic performance in metal‐based drug ...
J. V. Fontes, M. E. F. Agnoli, G. Clauss, M. S. A. Garcia, A. V. P. Ferreira, G. A. Antoniucci, A. L. Costa‐Oliveira, A.C.G. Jardim, D. C. Miguel, C. Abbehausen   +9 more
wiley   +1 more source

Oropouche virus: clinical, epidemiological, and molecular aspects of a neglected orthobunyavirus. [PDF]

, 2017
Oropouche virus (OROV) is an important cause of arboviral illness in Latin American countries, more specifically in the Amazon region of Brazil, Venezuela and Peru, as well as in other countries such as Panama.
Acrani, Gustavo Olszanski, Cardoso, Jedson Ferreira, da Rosa, Jorge Fernando Travassos, de Paula Pinheiro, Francisco, de Souza, William Marciel, Figueiredo, Mário Luiz, Nunes, Márcio Roberto Teixeira   +6 more
core   +1 more source

Integrating Citizen Science and Remote Sensing Data to Identify Key Environmental Factors Influencing H5N1 Avian Influenza Virus Potential Spillover Risk in the Philippines

GeoHealth, Volume 9, Issue 8, August 2025.
Abstract Highly pathogenic avian influenza (HPAI) virus presents a serious threat to poultry and public health worldwide, with transmission dynamics shaped by avian migration patterns and environmental conditions. Recent outbreaks in the Philippines highlight the urgent need for effective control measures.
John Oliver Sayseng, Ting‐Wu Chuang
wiley   +1 more source

Seroprevalence of Chikungunya and O'nyong‐nyong Viruses in Senegal, West Africa

Journal of Medical Virology, Volume 97, Issue 3, March 2025.
ABSTRACT Arthritogenic alphaviruses such as chikungunya (CHIKV) and o'nyong‐nyong (ONNV) viruses have shown capacity to cause widespread epidemics, with recurrent and sporadic outbreaks occurring throughout sub‐Saharan Africa. We analyzed the seroprevalence for CHIKV and ONNV in 470 non‐febrile subjects from three regions in Senegal (Sindia, 2018 ...
Prince Baffour Tonto, Mouhamad Sy, Ibrahima Mbaye Ndiaye, Mariama Toure, Amy Gaye, Mariama Aidara, Amadou Moctar Mbaye, Abdoulaye Kane Dia, Mamadou Alpha Diallo, Jules Francois Gomis, Mamadou Samb Yade, Younous Diedhiou, Baba Dieye, Khadim Diongue, Mame Cheikh Seck, Aida S. Badiane, Bobby Brooke Herrera, Daouda Ndiaye   +17 more
wiley   +1 more source

Effects of Chikungunya virus immunity on Mayaro virus disease and epidemic potential [PDF]

Scientific Reports, 2019
AbstractMayaro virus (MAYV) causes an acute febrile illness similar to that produced by chikungunya virus (CHIKV), an evolutionary relative in the Semliki Forest virus complex of alphaviruses. MAYV emergence is typically sporadic, but recent isolations and outbreaks indicate that the virus remains a public health concern.
Emily M. Webb, Sasha R. Azar, Sherry L. Haller, Rose M. Langsjoen, Candace E. Cuthbert, Anushka T. Ramjag, Huanle Luo, Kenneth Plante, Tian Wang, Graham Simmons, Christine V. F. Carrington, Scott C. Weaver, Shannan L. Rossi, Albert J. Auguste   +13 more
openaire   +2 more sources

Alphavirus nsP2: A Multifunctional Regulator of Viral Replication and Promising Target for Anti‐Alphavirus Therapies

Reviews in Medical Virology, Volume 35, Issue 2, March 2025.
ABSTRACT Alphaviruses are re‐emerging vector‐born pathogens that cause arthralgia or encephalitic diseases on a global scale. While a vaccine against chikungunya virus was recently approved, no vaccines currently exist for other alphaviruses, nor are there antiviral drugs for the treatment of alphavirus infections. Alphaviruses have positive‐strand RNA
Sainan Wang, Suresh Mahalingam, Andres Merits   +2 more
wiley   +1 more source

Two Birds With One Stone: RNA Virus Strategies to Manipulate G3BP1 and Other Stress Granule Components

WIREs RNA, Volume 16, Issue 2, March/April 2025.
Stress granules emerging during viral infection can play both pro‐ and antiviral roles. RNA viruses use various strategies to antagonize their formation, including the degradation, inhibition, or sequestration of G3BP1, a key stress granule protein. However, biochemical and structural insights into these mechanisms have been reported for only a handful
Moh Egy Rahman Firdaus, Eliana Dukhno, Rupali Kapoor, Piotr Gerlach   +3 more
wiley   +1 more source

New records and epidemiological potential of certain species of mosquito (Diptera, Culicidae) in the State of Rio Grande do Sul, Brazil [PDF]

, 2010
INTRODUÇÃO: A vigilância entomológica tem se mostrado uma importante estratégia de monitoramento da fauna de culicídeos com vistas a predizer o risco de exposição a espécies vetoras de patógenos.
ALMEIDA, Marco Antônio Barreto de, CARDOSO, Jáder da Cruz, FERNANDES, Aristides, FONSECA, Daltro Fernandes da, PAULA, Marcia Bicudo de, SALLUM, Maria Anice Mureb, SANTOS, Edmilson dos   +6 more
core   +1 more source

Antiviral Activities of Silymarin and Derivatives

Molecules, 2019
Silymarin flavonolignans are well-known agents that typically possess antioxidative, anti-inflammatory, and hepatoprotective functions. Recent studies have also documented the antiviral activities of silymarin and its derivatives against several viruses,
Ching-Hsuan Liu, Alagie Jassey, Hsin-Ya Hsu, Liang-Tzung Lin   +3 more
doaj   +1 more source