Results 71 to 80 of about 1,112,577 (175)

Monodentate Phosphine Modulation in Cyclometallated Platinum(II) Complexes for Antileishmanial, Antiviral, and Antitumor Applications

ChemMedChem, Volume 21, Issue 4, 25 February 2026.
Schematic representation depicting the influence of phosphine ligand identity on the biological and physicochemical characteristics of Pt(II) complexes: PTA promotes antileishmanial activity, PPh2(Php–COOH) strengthens antiviral activity, and TCEP enhances fluorescence.
Antonio A. de Oliveira‐Neto, Gustavo Clauss, Jennyfer Castro, Marcus S. A. Garcia, Natasha M. Cassani, Bruna C. Sandim, Ana Laura C. Oliveira, Stephanie P. B. Reyes, Nádija N. P. da Silva, Fillipe V. Rocha, Ana C. G. Jardim, Danilo C. Miguel, Camilla Abbehausen   +12 more
wiley   +1 more source

Unveiling the Molecular Profile and Antiviral Potential of Costus arabicus L. Against Zika Virus

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
Analysis of the chemical profile and antiviral potential of Costus arabicus L. extracts. ABSTRACT Widely used in Brazilian folk medicine, Costus arabicus L. (Canarana) is a herbaceous plant with promising pharmacological potential. Here, we profile the molecular composition of extracts from different plant organs and evaluate their in vitro activity ...
Alice Rhelly V. Carvalho, José Diogo E. Reis, Ariane Coelho Ferraz, Marília Bueno da Silva Menegatto, Juliana da C. Lopes, Sônia das G. S. R. Pamplona, Milton N. da Silva, Cintia Lopes de Brito Magalhães, Paulo Wender P. Gomes, Consuelo Yumiko Yoshioka e Silva   +9 more
wiley   +1 more source

A novel live-attenuated vaccine candidate for mayaro Fever. [PDF]

, 2014
Mayaro virus (MAYV) is an emerging, mosquito-borne alphavirus that causes a dengue-like illness in many regions of South America, and which has the potential to urbanize.
Forrester-Soto
core   +1 more source

Bee products as alternatives in the treatment of viral infections

Journal of the Science of Food and Agriculture, Volume 106, Issue 1, Page 33-54, 15 January 2026.
Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba, Łukasz Marek, Jerzy Stojko, Anna Rzepecka‐Stojko   +3 more
wiley   +1 more source

Arrival of Oropouche Virus in a Nonendemic Area in Northeastern Brazil, 2024

Journal of Medical Virology, Volume 98, Issue 1, January 2026.
ABSTRACT Orthobunyavirus oropoucheense (OROV) causes Oropouche fever, which exhibits symptoms similar to those of other arboviral diseases. Although it has historically been restricted to the Amazon region, the virus has recently spread to other areas of Brazil.
Jean P. M. Nascimento, Thiago P. G. Araújo, Mykaella A. Araújo, Mateus M. G. Arruda, Vitória P. Simplicio, Emelly B. Calheiros, Aline C. Pereira e Silva, Laura M. N. Silva, Marcus R. Santos, Magliones C. Lima, Hazerral O. Santos, Ênio J. Bassi, Alessandra A. Borges, Anderson B. Leite, Abelardo Silva‐Júnior   +14 more
wiley   +1 more source

Clinical, Serological, and Molecular Profile of Dengue Patients With Warning Signs During the 2024 Outbreak in Belo Horizonte, Brazil

Journal of Medical Virology, Volume 98, Issue 1, January 2026.
ABSTRACT Dengue poses a significant arboviral threat in Brazil, with 2024 recording the largest outbreak to date. This prospective observational study was conducted during the 2024 outbreak with unvaccinated patients at Eduardo de Menezes Hospital, Belo Horizonte.
Samille Henriques Pereira, Ana Paula Moreira Franco‐Luiz, Camila Tita Nogueira, Guilherme Otávio Varino Cornélio, Adelina Machado de Carvalho Nogueira, Vírginia Antunes de Andrade, Silvia Hees de Carvalho, Karen Cecília de Lima Torres, Vanessa Peruhype‐Magalhães, Olindo Assis Martins‐Filho, Jordana Grazziela Alves Coelho‐dos‐Reis, Andréa Teixeira‐Carvalho, Flávio Guimarães da Fonseca, Pedro Augusto Alves   +13 more
wiley   +1 more source

Antiviral Activities of Silymarin and Derivatives

Molecules, 2019
Silymarin flavonolignans are well-known agents that typically possess antioxidative, anti-inflammatory, and hepatoprotective functions. Recent studies have also documented the antiviral activities of silymarin and its derivatives against several viruses,
Ching-Hsuan Liu, Alagie Jassey, Hsin-Ya Hsu, Liang-Tzung Lin   +3 more
doaj   +1 more source

Exploring Bioactive Metabolites From Fusarium falciforme and Aspergillus terreus Isolated From Protease‐Rich Fruits: Antifungal, Antitrypanosomal, and Enzymatic Inhibitory Activities

Chemistry &Biodiversity, Volume 22, Issue 11, November 2025.
Metabolites from fungi isolated from protease rich‐fruits displayed antifungal, antitrypanosomal and enzymatic inhibitory activities. ABSTRACT Fungal secondary metabolites display remarkable chemical diversity and biological potential, with applications in agriculture and pharmaceuticals. This study isolated and characterized bioactive metabolites from
Gabriela de Oliveira Almeida, Vitor de Souza Mazucato, Ludmilla Tonani, Marcia Regina von Zeska Kress, Gisele Barbosa, Renata Krogh, Adriano Defini Andricopulo, Leonardo Luiz Gomes Ferreira, Paulo Cezar Vieira   +8 more
wiley   +1 more source

The Halogen Effect in [Cu(NHC)X] Compounds: A Case Study on the Anti‐Leishmania and Antiviral Activity of [Cu(IPr)X]

ChemistrySelect, Volume 10, Issue 31, August 15, 2025.
This study explores how changing halidesfrom Cl to Iinfluences ionic radius, antioxidant activity, and lipophilicity. These shifts significantly impact the biological potency of [Cu(IPr)X] compounds against Leishmania parasites and arboviruses. A strategic tweak in halogen identity paves the way for enhanced therapeutic performance in metal‐based drug ...
J. V. Fontes, M. E. F. Agnoli, G. Clauss, M. S. A. Garcia, A. V. P. Ferreira, G. A. Antoniucci, A. L. Costa‐Oliveira, A.C.G. Jardim, D. C. Miguel, C. Abbehausen   +9 more
wiley   +1 more source

Unexpected arboviruses found in an epidemiological surveillance of acute tropical febrile syndrome in the department of Meta, Eastern Colombia

Journal of Infection and Public Health
Background: Nonspecific acute tropical febrile illnesses (NEATFI) are common in the Latin American tropics. Dengue, Chikungunya, Zika, Mayaro, and Usutu, among others, can coexist in the American tropics.
Liliana Sánchez-Lerma, Andres Rojas-Gulloso, Jorge Miranda, Vanesa Tique, Luz Helena Patiño, Derly Rodriguez, Verónica Contreras, Alberto Paniz-Mondolfi, Norma Pavas, Juan David Ramírez, Salim Mattar   +10 more
doaj   +1 more source