Results 81 to 90 of about 1,037,494 (173)

Prolonged polyarthralgia in a German traveller with Mayaro virus infection without inflammatory correlates

open access: yes, 2013
BackgroundMayaro virus is endemic in South America and sporadic outbreaks have been described. It causes a dengue-like febrile illness accompanied by severe and long-lasting polyarthralgias. Outside endemic regions, however, the disease is not well known
Panning, Marcus   +4 more
core   +1 more source

Alphavirus nsP2: A Multifunctional Regulator of Viral Replication and Promising Target for Anti‐Alphavirus Therapies

open access: yesReviews in Medical Virology, Volume 35, Issue 2, March 2025.
ABSTRACT Alphaviruses are re‐emerging vector‐born pathogens that cause arthralgia or encephalitic diseases on a global scale. While a vaccine against chikungunya virus was recently approved, no vaccines currently exist for other alphaviruses, nor are there antiviral drugs for the treatment of alphavirus infections. Alphaviruses have positive‐strand RNA
Sainan Wang   +2 more
wiley   +1 more source

Quercetin and quercetin 3-O-glycosides from Bauhinia longifolia (Bong.) Steud. show anti-Mayaro virus activity

open access: yesParasites & Vectors, 2014
Background The arthropod-borne Mayaro virus (MAYV) causes ‘Mayaro fever’, a disease of medical significance, primarily affecting individuals in permanent contact with forested areas in tropical South America. Recently, MAYV has attracted attention due to
Alda E dos Santos   +7 more
doaj   +1 more source

Two Birds With One Stone: RNA Virus Strategies to Manipulate G3BP1 and Other Stress Granule Components

open access: yesWIREs RNA, Volume 16, Issue 2, March/April 2025.
Stress granules emerging during viral infection can play both pro‐ and antiviral roles. RNA viruses use various strategies to antagonize their formation, including the degradation, inhibition, or sequestration of G3BP1, a key stress granule protein. However, biochemical and structural insights into these mechanisms have been reported for only a handful
Moh Egy Rahman Firdaus   +3 more
wiley   +1 more source

Human Antibody Responses to Emerging Mayaro Virus and Cocirculating Alphavirus Infections Examined by Using Structural Proteins from Nine New and Old World Lineages

open access: yesmSphere, 2018
Mayaro virus (MAYV), Venezuelan equine encephalitis virus (VEEV), and chikungunya virus (CHIKV) are vector-borne alphaviruses that cocirculate in South America.
Jessica L. Smith   +10 more
doaj   +1 more source

Identification of Mayaro Virus Genotype D in Rondônia, Brazil. [PDF]

open access: yesAm J Trop Med Hyg
ABSTRACT. The Mayaro virus (MAYV) is a significant reemerging arbovirus of public health concern, responsible for outbreaks in several countries including Brazil. In this study, 857 samples of patients with acute fever in the state of Rondônia, Brazil, were analyzed by reverse transcriptase qualitative polymerase chain reaction (RT-qPCR) to detect Zika,
Pimentel EP   +7 more
europepmc   +3 more sources

Chikungunya Virus: Unveiling Its Global Impact (2002–2024)

open access: yesInterdisciplinary Perspectives on Infectious Diseases, Volume 2025, Issue 1, 2025.
Chikungunya virus (CHIKV), an arbovirus transmitted by Aedes mosquitoes, has caused massive global epidemics, where it causes periodic outbreaks of febrile illness. In recent years, it has afflicted populations of Africa, South America, and Southeast Asia.
Rakhi Issrani   +8 more
wiley   +1 more source

A Novel Self‐Amplifying mRNA with Decreased Cytotoxicity and Enhanced Protein Expression by Macrodomain Mutations

open access: yesAdvanced Science, Volume 11, Issue 43, November 20, 2024.
This research shows an example that reducing innate immunogenicity to increase payload protein expression of self‐amplifying RNA via a single mutation in the macrodomain. The mutant saRNA attenuates the activation of the double‐stranded RNA sensor as well as the downstream interferon response.
Yue Gong   +5 more
wiley   +1 more source

Studies on the replication of Mayaro virus grown in interferon treated cells

open access: yesMemorias do Instituto Oswaldo Cruz, 1994
Mayaro virus grown in interferon treated infected cells has been characterized with regard to its ability to replicate in vertebrate (TC7) and invertebrate (Aedes albopictus) cells.
M. C. S. Rebello   +3 more
doaj   +1 more source

Clinical signs observed in Balb / c mice during virus infection Mayaro.

open access: yes, 2019
Clinical signs observed in Balb / c mice during virus infection Mayaro.
Franciele Martins Santos (6664013)   +10 more
core   +1 more source

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