Results 1 to 10 of about 10,340 (193)

Mosquito Saliva Reshapes Alphavirus Infection and Immunopathogenesis [PDF]

Journal of Virology, 2018
Alphaviruses are transmitted to humans via bites of infected mosquitoes. Although alphaviruses have caused a wide range of outbreaks and crippling disease, the availability of licensed vaccines or antiviral therapies remains limited.
Lisa F. P. Ng, Siew-Wai Fong, R. Manjunatha Kini   +2 more
core   +3 more sources

Chikungunya Virus in US Travelers Returning from India, 2006

Emerging Infectious Diseases, 2007
Chikungunya virus (CHIKV), a mosquitoborne alphavirus; is endemic in Africa and Asia. In 2005–2006, CHIKV epidemics were reported in islands in the Indian Ocean and in southern India.
Robert S. Lanciotti, Olga L. Kosoy, Janeen J. Laven, Amanda J. Panella, Jason O. Velez, Amy J. Lambert, Grant L. Campbell   +6 more
doaj   +1 more source

Isolation of Complete Equine Encephalitis Virus Genome from Human Swab Specimen, Peru

Emerging Infectious Diseases, 2018
While studying respiratory infections in Peru, we identified Venezuelan equine encephalitis virus (VEEV) in a nasopharyngeal swab, indicating that this alphavirus can be present in human respiratory secretions.
Diana Juarez, Carolina Guevara, Michael Wiley, Armando Torre, Gustavo Palacios, Eric S. Halsey, Sonia Ampuero, Mariana Leguia   +7 more
doaj   +1 more source

Contribution of the Golgi apparatus in morphogenesis of a virus-induced cytopathic vacuolar system

Life Science Alliance, 2022
Electron tomography reveals four classes of cytopathic vesicles-II (CPV-II) stemming from the host Golgi apparatus after Venezuelan equine encephalitis virus infection.
Ranjan Sengupta, Elaine M Mihelc, Stephanie Angel, Jason K Lanman, Richard J Kuhn, Robert V Stahelin   +5 more
doaj   +1 more source

Modulation of monocyte-driven myositis in alphavirus infection reveals a role for CX3CR1+ macrophages in tissue repair [PDF]

, 2020
Arthritogenic alphaviruses such as Ross River and Chikungunya viruses cause debilitating muscle and joint pain and pose significant challenges in the light of recent outbreaks.
Liu, X, Taylor, Adam, Getts, Daniel R, Tharmarajah, Kothila, Liu, Xiang, Vider, J, Daniel R. Getts, Nicholas P. West, Zaid, A, Zaid, Ali, Freitas, JR, Getts, DR, Mahalingam, Suresh, Chen, Weiqiang, Weiqiang Chen, Kuo-Ching Sheng, Chen, W, Herrero, LJ, Xiang Liu, Mackay, LK, Jelena Vider, Mackay, Laura K, Mostafavi, H, West, NP, Laura K. Mackay, Joseph R. Freitas, Mostafavi, Helen, West, Nicholas P, Mahalingam, S, Taylor, A, Sheng, Kuo-Ching, Freitas, Joseph R, King, Nicholas JC, Sheng, KC, Foo, Suan-Sin, Nicholas J. C. King, Ali Zaid, Helen Mostafavi, Tharmarajah, K, King, NJC, Kothila Tharmarajah, Adam Taylor, Lara J. Herrero, Foo, SS, Vider, Jelena, Suresh Mahalingam, Herrero, Lara J, Suan-Sin Foo   +47 more
core   +1 more source

Inhibitors of Venezuelan Equine Encephalitis Virus Identified Based on Host Interaction Partners of Viral Non-Structural Protein 3

Viruses, 2021
Venezuelan equine encephalitis virus (VEEV) is a new world alphavirus and a category B select agent. Currently, no FDA-approved vaccines or therapeutics are available to treat VEEV exposure and resultant disease manifestations. The C-terminus of the VEEV
Allison Bakovic, Nishank Bhalla, Farhang Alem, Catherine Campbell, Weidong Zhou, Aarthi Narayanan   +5 more
doaj   +1 more source

Type I interferon reaction to viral infection in interferon-competent, immortalized cell lines from the African fruit bat Eidolon helvum. [PDF]

PLoS ONE, 2011
Bats harbor several highly pathogenic zoonotic viruses including Rabies, Marburg, and henipaviruses, without overt clinical symptoms in the animals. It has been suspected that bats might have evolved particularly effective mechanisms to suppress viral ...
Susanne E Biesold, Daniel Ritz, Florian Gloza-Rausch, Robert Wollny, Jan Felix Drexler, Victor M Corman, Elisabeth K V Kalko, Samuel Oppong, Christian Drosten, Marcel A Müller   +9 more
doaj   +1 more source

Investigating the Role of Sphingosine Kinases During Alphavirus Infection

, 2022
Several alphaviruses, critical human pathogens, have re-emerged in recent years. Alphaviruses are found on all continents and infect both invertebrates and vertebrates, including some aquatic animals.
Oyewole, Opeoluwa
core  

Alphavirus nsP2: A Multifunctional Regulator of Viral Replication and Promising Target for Anti-Alphavirus Therapies

Alphaviruses are re-emerging vector-born pathogens that cause arthralgia or encephalitic diseases on a global scale. While a vaccine against chikungunya virus was recently approved, no vaccines currently exist for other alphaviruses, nor are there ...
Merits, Andres, Wang, Sainan, Mahalingam, Suresh   +2 more
core   +1 more source

Modulation of Monocyte-Driven Myositis in Alphavirus Infection Reveals a Role for CX₃CR1⁺ Macrophages in Tissue Repair

mBio, 2020
Arthritogenic alphaviruses such as Ross River and Chikungunya viruses cause debilitating muscle and joint pain and pose significant challenges in the light of recent outbreaks.
Ali Zaid, Kothila Tharmarajah, Helen Mostafavi, Joseph R. Freitas, Kuo-Ching Sheng, Suan-Sin Foo, Weiqiang Chen, Jelena Vider, Xiang Liu, Nicholas P. West, Lara J. Herrero, Adam Taylor, Laura K. Mackay, Daniel R. Getts, Nicholas J. C. King, Suresh Mahalingam   +15 more
doaj   +1 more source