Chikungunya Virus Infection during Pregnancy, Réunion, France, 2006
Mother-to-child transmission of chikungunya virus was reported during the 2005–2006 outbreak on Réunion Island, France. To determine the effects of this virus on pregnancy outcomes, we conducted a study of pregnant women in Réunion in 2006.
Xavier Fritel +15 more
doaj +1 more source
A novel mechanism underlying the innate immune response induction upon viral-dependent replication of host cell mRNA: A mistake of +sRNA viruses' replicases [PDF]
Viruses are lifeless particles designed for setting virus-host interactome assuring a new generation of virions for dissemination. This interactome generates a pressure on host organisms evolving mechanisms to neutralize viral infection, which places the
Colombo, Maria Isabel +1 more
core +2 more sources
Infection of Mammals and Mosquitoes by Alphaviruses: Involvement of Cell Death
Alphaviruses, such as the chikungunya virus, are emerging and re-emerging viruses that pose a global public health threat. They are transmitted by blood-feeding arthropods, mainly mosquitoes, to humans and animals.
Lucie Cappuccio, Carine Maisse
doaj +1 more source
Chikungunya virus: an update on the biology and pathogenesis of this emerging pathogen [PDF]
Re-emergence of chikungunya virus, a mosquito-transmitted pathogen, is of serious public health concern. In the past 15 years, after decades of infrequent, sporadic outbreaks, the virus has caused major epidemic outbreaks in Africa, Asia, the Indian ...
Burt, Felicity J +12 more
core +1 more source
Imported Arbovirus Infections in Canada 1974-89
From 1974 to 1989, sera from symptomatic patients with histories of recent travel outside Canada were tested for antibodies to several arboviruses, principally of the alphavirus and flavivirus families.
Harvey Artsob, Leslie Spence
doaj +1 more source
IFIT1 differentially interferes with translation and replication of alphavirus genomes and promotes induction of type I interferon [PDF]
Alphaviruses are a group of widely distributed human and animal pathogens. It is well established that their replication is sensitive to type I IFN treatment, but the mechanism of IFN inhibitory function remains poorly understood.
Atasheva, Svetlana +8 more
core +4 more sources
Our knowledge of alphavirus genetic diversity is mainly based on viruses isolated from anthropophilic mosquito species, humans, and livestock during outbreaks.
Selina Laura Graff +9 more
doaj +1 more source
Alphavirus-Induced Membrane Rearrangements during Replication, Assembly, and Budding
Alphaviruses are arthropod-borne viruses mainly transmitted by hematophagous insects that cause moderate to fatal disease in humans and other animals. Currently, there are no approved vaccines or antivirals to mitigate alphavirus infections.
Zeinab Elmasri +2 more
doaj +1 more source
Diversity in viral anti-PKR mechanisms: A remarkable case of evolutionary convergence [PDF]
Most viruses express during infection products that prevent or neutralize the effect of the host dsRNA activated protein kinase (PKR). Translation of Sindbis virus (SINV) mRNA escapes to PKR activation and eIF2 phosphorylation in infected cells by a ...
Domingo-Gil, Elena +4 more
core +1 more source
Spatial and Temporal Analysis of Alphavirus Replication and Assembly in Mammalian and Mosquito Cells
Sindbis virus (SINV [genus Alphavirus, family Togaviridae]) is an enveloped, mosquito-borne virus. Alphaviruses cause cytolytic infections in mammalian cells while establishing noncytopathic, persistent infections in mosquito cells.
Joyce Jose +2 more
doaj +1 more source

