Results 51 to 60 of about 10,340 (193)
Early Events in Alphavirus Replication Determine the Outcome of Infection [PDF]
Journal of Virology, 2012 ABSTRACT Alphaviruses are a group of important human and animal pathogens. They efficiently replicate to high titers in vivo and in many commonly used cell lines of vertebrate origin. They have also evolved effective means of interfering with development of the innate immune
Ilya, Frolov +4 more
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Alphavirus infection triggers antiviral RNAi immunity in mammals
Cell Reports, 2023 RNA interference (RNAi) is a well-established antiviral immunity. However, for mammalian somatic cells, antiviral RNAi becomes evident only when viral suppressors of RNAi (VSRs) are disabled by mutations or VSR-targeting drugs, thereby limiting its scope as a mammalian immunity.
Jing Kong +7 more
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Infection of Mammals and Mosquitoes by Alphaviruses: Involvement of Cell Death
Cells, 2020 Alphaviruses, such as the chikungunya virus, are emerging and re-emerging viruses that pose a global public health threat. They are transmitted by blood-feeding arthropods, mainly mosquitoes, to humans and animals.
Lucie Cappuccio, Carine Maisse
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Review of Phytochemical Compounds as Antiviral Agents against Arboviruses from the Genera Flavivirus and Alphavirus [PDF]
, 2020 Arboviruses are a diverse group of viruses that are among the major causes of emerging infectious diseases. Arboviruses from the genera flavivirus and alphavirus are the most important human arboviruses from a public health perspective.
Sewell, Robert D. E. +4 more
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Neurological Sequelae Resulting from Encephalitic Alphavirus Infection [PDF]
Frontiers in Microbiology, 2016 The recent surge in viral clinical cases and associated neurological deficits have reminded us that viral infections can lead to detrimental, long-term effects, termed sequelae, in survivors. Alphaviruses are enveloped, single-stranded positive-sense RNA viruses in the Togaviridae family.
Ronca, Shannon E. +2 more
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Frontiers in MicrobiologyOur knowledge of alphavirus genetic diversity is mainly based on viruses isolated from anthropophilic mosquito species, humans, and livestock during outbreaks.
Selina Laura Graff +9 more
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Alphavirus-Induced Membrane Rearrangements during Replication, Assembly, and Budding
Pathogens, 2021 Alphaviruses are arthropod-borne viruses mainly transmitted by hematophagous insects that cause moderate to fatal disease in humans and other animals. Currently, there are no approved vaccines or antivirals to mitigate alphavirus infections.
Zeinab Elmasri +2 more
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Host-pathogen interactions during alphavirus infection
, 2021 Arthritogenic alphavirus infection causes debilitating pain in the joints and muscles with many patients experiencing such symptoms chronically. However, there is insufficient evidence to explain the underlying causes behind symptoms of persistent ...
Lim, Elisa X
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Noncapped Alphavirus Genomic RNAs and Their Role during Infection [PDF]
Journal of Virology, 2015 ABSTRACT Alphaviruses are enveloped positive-sense RNA viruses that exhibit a wide host range consisting of vertebrate and invertebrate species. Previously we have reported that the infectivity of Sindbis virus (SINV), the model alphavirus, was largely a function of the cell line producing the viral particles.
K J, Sokoloski +4 more
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In vitro study of Hesperetin and Hesperidin as inhibitors of zika and chikungunya virus proteases.
PLoS ONE, 2021 The potential outcome of flavivirus and alphavirus co-infections is worrisome due to the development of severe diseases. Hundreds of millions of people worldwide live under the risk of infections caused by viruses like chikungunya virus (CHIKV, genus ...
Raphael J Eberle +8 more
doaj +1 more source