Results 31 to 40 of about 9,810 (173)
Alphavirus infection triggers antiviral RNAi immunity in mammals
Cell Reports, 2023 RNA interference (RNAi) is a well-established antiviral immunity. However, for mammalian somatic cells, antiviral RNAi becomes evident only when viral suppressors of RNAi (VSRs) are disabled by mutations or VSR-targeting drugs, thereby limiting its scope as a mammalian immunity.
Jing Kong +7 more
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Neurological Sequelae Resulting from Encephalitic Alphavirus Infection [PDF]
Frontiers in Microbiology, 2016 The recent surge in viral clinical cases and associated neurological deficits have reminded us that viral infections can lead to detrimental, long-term effects, termed sequelae, in survivors. Alphaviruses are enveloped, single-stranded positive-sense RNA viruses in the Togaviridae family.
Ronca, Shannon E. +2 more
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Imported Arbovirus Infections in Canada 1974-89
Canadian Journal of Infectious Diseases, 1991 From 1974 to 1989, sera from symptomatic patients with histories of recent travel outside Canada were tested for antibodies to several arboviruses, principally of the alphavirus and flavivirus families.
Harvey Artsob, Leslie Spence
doaj +1 more source
Alphavirus-Induced Membrane Rearrangements during Replication, Assembly, and Budding
Pathogens, 2021 Alphaviruses are arthropod-borne viruses mainly transmitted by hematophagous insects that cause moderate to fatal disease in humans and other animals. Currently, there are no approved vaccines or antivirals to mitigate alphavirus infections.
Zeinab Elmasri +2 more
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Noncapped Alphavirus Genomic RNAs and Their Role during Infection [PDF]
Journal of Virology, 2015 ABSTRACT Alphaviruses are enveloped positive-sense RNA viruses that exhibit a wide host range consisting of vertebrate and invertebrate species. Previously we have reported that the infectivity of Sindbis virus (SINV), the model alphavirus, was largely a function of the cell line producing the viral particles.
K J, Sokoloski +4 more
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Frontiers in MicrobiologyOur knowledge of alphavirus genetic diversity is mainly based on viruses isolated from anthropophilic mosquito species, humans, and livestock during outbreaks.
Selina Laura Graff +9 more
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Spatial and Temporal Analysis of Alphavirus Replication and Assembly in Mammalian and Mosquito Cells
mBio, 2017 Sindbis virus (SINV [genus Alphavirus, family Togaviridae]) is an enveloped, mosquito-borne virus. Alphaviruses cause cytolytic infections in mammalian cells while establishing noncytopathic, persistent infections in mosquito cells.
Joyce Jose +2 more
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In vitro study of Hesperetin and Hesperidin as inhibitors of zika and chikungunya virus proteases.
PLoS ONE, 2021 The potential outcome of flavivirus and alphavirus co-infections is worrisome due to the development of severe diseases. Hundreds of millions of people worldwide live under the risk of infections caused by viruses like chikungunya virus (CHIKV, genus ...
Raphael J Eberle +8 more
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Riboflavin, a Potent Neuroprotective Vitamin: Focus on Flavivirus and Alphavirus Proteases
Microorganisms, 2022 Several neurotropic viruses are members of the flavivirus and alphavirus families. Infections caused by these viruses may cause long-term neurological sequelae in humans.
Raphael J. Eberle +7 more
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Journal of Fish Diseases, EarlyView.ABSTRACT Ectoparasites that penetrate host skin can act as biological or mechanical vectors for pathogens and, in some cases, serve as reservoirs. Crustacean ectoparasites of fish are potential vectors of pathogens, which is especially relevant for obligate pathogens (e.g., Aeromonas salmonicida) with limited seawater survival. Sea lice (Lepeophtheirus
B. Klimesova +9 more
wiley +1 more source