Results 21 to 30 of about 9,810 (173)

Perturbation of alphavirus and flavivirus infectivity by components of the bacterial cell wall [PDF]

open access: yesJournal of Virology, 2021
Abstract The impact of the host microbiota on arbovirus infections is currently not well understood. Arboviruses are viruses transmitted through the bites of infected arthropods, predominantly mosquitoes or ticks. The first site of arbovirus inoculation is the biting site in the host skin, which is colonized by a ...
Lana Langendries   +7 more
openaire   +2 more sources

Salmonid alphavirus (SAV)

open access: yesJournal of Veterinary Research, 2018
Salmonid alphavirus (SAV), genus Alphavirus, family Togaviridae, is a single-stranded RNA virus affecting Atlantic salmon (Salmo salar) and rainbow trout (Oncorhynchus mykiss). It is known to be responsible for pancreas disease (PD) and sleeping disease (
Deperasińska Izabela   +2 more
doaj   +1 more source

Berberine Chloride is an Alphavirus Inhibitor That Targets Nucleocapsid Assembly

open access: yesmBio, 2020
Alphaviruses are enveloped positive-sense RNA viruses that can cause serious human illnesses such as polyarthritis and encephalitis. Despite their widespread distribution and medical importance, there are no licensed vaccines or antivirals to combat ...
Judy J. Wan   +2 more
doaj   +1 more source

Anti-Alphaviral Alkaloids: Focus on Some Isoquinolines, Indoles and Quinolizidines

open access: yesMolecules, 2022
The discovery and the development of safe and efficient therapeutics against arthritogenic alphaviruses (e.g., chikungunya virus) remain a continuous challenge.
Anne-Laure Sandenon Seteyen   +5 more
doaj   +1 more source

Role of pentraxin 3 in shaping arthritogenic alphaviral disease: from enhanced viral replication to immunomodulation.

open access: yesPLoS Pathogens, 2015
The rising prevalence of arthritogenic alphavirus infections, including chikungunya virus (CHIKV) and Ross River virus (RRV), and the lack of antiviral treatments highlight the potential threat of a global alphavirus pandemic.
Suan-Sin Foo   +12 more
doaj   +1 more source

Chikungunya Virus Infection during Pregnancy, Réunion, France, 2006

open access: yesEmerging Infectious Diseases, 2010
Mother-to-child transmission of chikungunya virus was reported during the 2005–2006 outbreak on Réunion Island, France. To determine the effects of this virus on pregnancy outcomes, we conducted a study of pregnant women in Réunion in 2006.
Xavier Fritel   +15 more
doaj   +1 more source

Identification of 2,4-Diaminoquinazoline Derivative as a Potential Small-Molecule Inhibitor against Chikungunya and Ross River Viruses

open access: yesViruses, 2023
Alphaviruses are serious zoonotic threats responsible for significant morbidity, causing arthritis or encephalitis. So far, no licensed drugs or vaccines are available to combat alphaviral infections.
Amrita Saha   +5 more
doaj   +1 more source

The Host Non-Coding RNA Response to Alphavirus Infection

open access: yesViruses, 2023
Alphaviruses are important human and animal pathogens that can cause a range of debilitating symptoms and are found worldwide. These include arthralgic diseases caused by Old-World viruses and encephalitis induced by infection with New-World alphaviruses.
Mahgol Behnia, Steven B. Bradfute
openaire   +3 more sources

Infection of Mammals and Mosquitoes by Alphaviruses: Involvement of Cell Death

open access: yesCells, 2020
Alphaviruses, such as the chikungunya virus, are emerging and re-emerging viruses that pose a global public health threat. They are transmitted by blood-feeding arthropods, mainly mosquitoes, to humans and animals.
Lucie Cappuccio, Carine Maisse
doaj   +1 more source

Early Events in Alphavirus Replication Determine the Outcome of Infection [PDF]

open access: yesJournal of Virology, 2012
ABSTRACT Alphaviruses are a group of important human and animal pathogens. They efficiently replicate to high titers in vivo and in many commonly used cell lines of vertebrate origin. They have also evolved effective means of interfering with development of the innate immune
Ilya, Frolov   +4 more
openaire   +2 more sources

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