Sequelae and Animal Modeling of Encephalitic Alphavirus Infections [PDF]
Eastern (EEEV), Venezuelan (VEEV), and western equine encephalitis viruses (WEEV) are members of the genus Alphavirus, family Togaviridae. Typically spread by mosquitoes, EEEV, VEEV, and WEEV induce febrile illness that may develop into more severe ...
Rachel A. Reyna, Scott C. Weaver
doaj +7 more sources
Human Antibody Responses to Emerging Mayaro Virus and Cocirculating Alphavirus Infections Examined by Using Structural Proteins from Nine New and Old World Lineages [PDF]
Mayaro virus (MAYV), Venezuelan equine encephalitis virus (VEEV), and chikungunya virus (CHIKV) are vector-borne alphaviruses that cocirculate in South America.
Jessica L. Smith +10 more
doaj +5 more sources
Alphavirus Virulence Determinants
Alphaviruses are important pathogens that continue to cause outbreaks of disease in humans and animals worldwide. Diseases caused by alphavirus infections include acute symptoms of fever, rash, and nausea as well as chronic arthritis and severe-to-fatal ...
Margarita V. Rangel +1 more
doaj +4 more sources
Interactions of Alphavirus nsP3 Protein with Host Proteins
Alphaviruses are members of the Togaviridae family and are grouped into two categories: arthritogenic and encephalitic. Arthritogenic alphavirus infections, as the name implies, are associated with arthritic outcomes while encephalitic alphavirus ...
Tyler Lark +2 more
doaj +4 more sources
The search for antivirals to treat alphavirus infections
Alphaviruses are a group of viruses responsible for a variety of emerging and re-emerging human diseases. Although they do not generally cause life-threatening illnesses, they can lead to debilitating and chronic conditions.
Marcella Bassetto, Andrea Brancale
exaly +5 more sources
Background: Alphaviruses are transmitted by arthropod vectors and can be found worldwide. Alphaviruses of the Semliki Forest complex such as chikungunya virus (CHIKV), Mayaro virus (MAYV) or Ross River virus (RRV) cause acute febrile illness and long ...
Lisa Henss +8 more
doaj +4 more sources
Endemic and Epidemic Human Alphavirus Infections in Eastern Panama: An Analysis of Population-Based Cross-Sectional Surveys. [PDF]
Madariaga virus (MADV), has recently been associated with severe humanb disease in Panama, where the closely related Venezuelan equine encephalitis virus (VEEV) also circulates. In June, 2017, a fatal MADV infection was confirmed in a community of Darien
Carrera JP +20 more
europepmc +4 more sources
Salmonid alphavirus (SAV), genus Alphavirus, family Togaviridae, is a single-stranded RNA virus affecting Atlantic salmon (Salmo salar) and rainbow trout (Oncorhynchus mykiss). It is known to be responsible for pancreas disease (PD) and sleeping disease (
Deperasińska Izabela +2 more
doaj +3 more sources
Seroprevalence of alphavirus antibodies in a cross-sectional study in southwestern Tanzania suggests endemic circulation of chikungunya. [PDF]
BACKGROUND: To date, Alphavirus infections and their most prominent member, chikungunya fever, a viral disease which first became apparent in Tanzania in 1953, have been very little investigated in regions without epidemic occurrence.
Nina Weller +9 more
doaj +3 more sources
Insights into Antibody-Mediated Alphavirus Immunity and Vaccine Development Landscape
Alphaviruses are mosquito-borne pathogens distributed worldwide in tropical and temperate areas causing a wide range of symptoms ranging from inflammatory arthritis-like manifestations to the induction of encephalitis in humans.
Anthony Torres-Ruesta +2 more
doaj +2 more sources

