Results 71 to 80 of about 9,810 (173)

Variable effects of Wolbachia on alphavirus infection in Aedes aegypti

, 2023
2. Abstract Wolbachia pipientis (= Wolbachia ) has promise as a tool to suppress virus transmission by Aedes aegypti mosquitoes.
Brittany L. Dodson, Sujit Pujhari, Marco Brustolin, Hillery C. Metz, Jason L. Rasgon   +4 more
openaire   +2 more sources

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

Advanced Science, Volume 13, Issue 20, 9 April 2026.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang, Yi Liu, Zhiying Yao, Haolong Lai, Xiaoxin Chen, Ziqiu Wang, Yiqiong Bao, Tingting Li, Xiaoming Zhou, Xiabin Chen, Peiguo Yang   +10 more
wiley   +1 more source

Hunting in the Rainforest and Mayaro Virus Infection: An emerging Alphavirus in Ecuador

Journal of Global Infectious Diseases, 2011
Objectives: The objectives of this report were to document the potential presence of Mayaro virus infection in Ecuador and to examine potential risk factors for Mayaro virus infection among the personnel of a military garrison in the Amazonian rainforest.
Ricardo O Izurieta, Maurizio Macaluso, Douglas M Watts, Robert B Tesh, Bolivar Guerra, Ligia M Cruz, Sagar Galwankar, Sten H Vermund   +7 more
openaire   +3 more sources

“More” Artificial mRNAs: Beyond the Art of Nature

Advanced Science, Volume 13, Issue 20, 9 April 2026.
Inspired by nature yet transcending it, synthetic mRNA is being redesigned beyond the canonical architecture. This review highlights emerging forms—circular, branched, and self‐amplifying mRNAs—that expand stability, persistence, and functional control, illustrating how artificial mRNA is evolving into a new medium for programmable biological ...
Yuanzhe Cui, Minami Fukui, Hirohisa Ohno, Hirohide Saito   +3 more
wiley   +1 more source

CHIKUNGUNYA VIRUS: WHAT DO WE KNOW ABOUT THIS ARBOVIRUS INFECTION? (IN SPANISH)

Revista Ciencias Biomédicas, 2014
Introduction: for Colombia the arrival of the Chikungunya virus (CHIKV) constitutes a potential problem of public health due to in the country as much in rural as urban areas, the presence of the A.
Ochoa-Díaz Margarita María, De León-Benito Revollo Yéssika, Rodríguez-Quintero Gerson, Gómez-Camargo Doris Esther   +3 more
doaj  

DHHC enzymes in alphavirus glycoprotein acylation: A target for broad-spectrum antiviral therapy

Cell Reports
Summary: Alphaviruses are mosquito-transmitted viruses that cause severe zoonotic diseases. Their envelope glycoproteins, E1 and E2, undergo cysteine acylation, a process critical for virus infection but previously undefined mechanistically.
Xiaoling Li, Chaoyun Han, Wanjie Song, Zhiwen Jiang, Yunbiao Lu, Sainan Wang, Jie Chen, Yu Deng, Andres Merits, Wan-Ting He, Shuo Su, Michael Veit   +11 more
doaj   +1 more source

The Poisson CUSUM Chart for Monitoring Small Counts: Addressing the Estimation Uncertainty

Biometrical Journal, Volume 68, Issue 2, April 2026.
ABSTRACT This study addresses the impact of estimating in‐control parameters on the performance of the Poisson cumulative sum (CUSUM) chart in detecting an increase in the mean when the counts are small. To reduce false signals induced by estimation uncertainty, recommendations prescribe impractically large sample sizes or propose methods that widen ...
Stan Heidema, Ivo V. Stoepker, Ralph Huits, Edwin R. van den Heuvel   +3 more
wiley   +1 more source

Alphavirus Infection of the CNS: Entry, Dissemination, and Neurodegeneration

European Journal of Molecular & Clinical Medicine, 2015
Alphaviruses most often associated with neuroinvasive disease are limited to the Americas and include strains of EEEV, VEEV, and WEEV. The process of alphavirus entry into the CNS of infected vertebrates following challenge is not well-understood. It is thought that virus entry into the CNS depends on the inoculation route.
Phillips AT, Rico AB, Aboellail TA, Olson KE   +3 more
openaire   +1 more source

Triple Burden in the Democratic Republic of Congo: Climate Change, Armed Conflict, and the Silent Spread of Arboviruses. A Narrative Review

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background The Democratic Republic of Congo (DRC) faces a “triple burden” of public health threats which includes climate change, protracted armed conflict, and the under‐recognized spread of arboviral diseases. Arboviruses, such as dengue, chikungunya, Zika, and yellow fever, are transmitted by Aedes aegypti and Aedes albopictus mosquitoes ...
Stanis Donnang, Hermann Yokolo, Dujardin Makeda, Joshua Ekouo, Zubayer Shams, Johan Armel Domga Kaptso, Josias Silatchom Kamgang, Yann Valerin Waffo, Christian Tague   +8 more
wiley   +1 more source

The Role of Innate Cells During Alphavirus Chikungunya Infection

Viruses
Alphavirus chikungunya (CHIKV) is an arthropod-borne alphavirus of the Togaviridae family, transmitted primarily by Aedes aegypti and Ae. albopictus mosquitoes. CHIKV infection often results in debilitating manifestations that compromise quality of life and generate significant socioeconomic impacts.
Juliane Santos de França da Silva, Livian Maria Silva dos Santos, Célio Valdevino Ferreira Junior, Nathalie de Sena Pereira, Juliana Navarro Ueda Yaochite, Valter Ferreira de Andrade Neto, Paulo Marcos da Matta Guedes, Rafael Freitas De Oliveira França, Ramayana Morais de Medeiros Brito, Manuela Sales Lima Nascimento   +9 more
openaire   +2 more sources