Results 71 to 80 of about 819,223 (194)

Effects of Palmitoylation of Replicase Protein nsP1 on Alphavirus Infection

Journal of Virology, 2000
ABSTRACT The membrane-associated alphavirus RNA replication complex contains four virus-encoded subunits, the nonstructural proteins nsP1 to nsP4. Semliki Forest virus (SFV) nsP1 is hydrophobically modified by palmitoylation of cysteines 418 to 420.
T, Ahola, P, Kujala, M, Tuittila, T, Blom, P, Laakkonen, A, Hinkkanen, P, Auvinen   +6 more
openaire   +3 more sources

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, Volume 150, Issue 7, Page 990-1015, August 2026.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source

Chikungunya Vaccine Candidates: Current Landscape and Future Prospects

Drug Design, Development and Therapy, 2022
Christin Schmidt, Barbara S Schnierle Paul-Ehrlich-Institut, Department of Virology, Section AIDS and Newly Emerging Pathogens, Langen, GermanyCorrespondence: Barbara S Schnierle, Paul-Ehrlich-Institut, Department of Virology, Section AIDS and newly ...
Schmidt C, Schnierle BS
doaj  

Will Mayaro virus be responsible for the next outbreak of an arthropod-borne virus in Brazil?

Brazilian Journal of Infectious Diseases, 2017
Mayaro virus is an alphavirus from the Togaviridae family and is transmitted mainly by Hemagogus mosquitoes. This virus circulates in high-density tropical forests or rural areas of Central and South America causing a disease characterized by high-grade ...
Danillo Lucas Alves Esposito, Benedito Antonio Lopes da Fonseca   +1 more
doaj   +1 more source

Modulation of Monocyte-Driven Myositis in Alphavirus Infection Reveals a Role for CX₃CR1⁺ Macrophages in Tissue Repair

mBio, 2020
Arthritogenic alphaviruses such as Ross River and Chikungunya viruses cause debilitating muscle and joint pain and pose significant challenges in the light of recent outbreaks.
Ali Zaid, Kothila Tharmarajah, Helen Mostafavi, Joseph R. Freitas, Kuo-Ching Sheng, Suan-Sin Foo, Weiqiang Chen, Jelena Vider, Xiang Liu, Nicholas P. West, Lara J. Herrero, Adam Taylor, Laura K. Mackay, Daniel R. Getts, Nicholas J. C. King, Suresh Mahalingam   +15 more
doaj   +1 more source

Economic effects of disease outbreaks on U.S. salmonid farms

Journal of the World Aquaculture Society, Volume 57, Issue 4, August 2026.
Abstract The U.S. salmonid industry is the second‐largest finfish sector of U.S. aquaculture, contributing $886 million and more than 2000 jobs to the U.S. economy in 2022. The goal of this study was to develop an economic analysis of the impact of losses from disease outbreaks to the U.S. salmonid industry.
Carole Engle, Shraddha Hegde, Jonathan van Senten, Ganesh Kumar, Christine Ellis, Gary Fornshell   +5 more
wiley   +1 more source

Challenges and emerging trends in fish vaccine platforms, delivery methods, and field performance for sustainable aquaculture: A scoping review

Journal of the World Aquaculture Society, Volume 57, Issue 4, August 2026.
Abstract Fish vaccination has been practiced globally for several decades and is increasingly recognized as a cornerstone of sustainable disease management in aquaculture, offering an effective alternative to antibiotic and chemotherapeutic use. This PRISMA‐ScR guided Scoping Review synthesized evidence from 173 peer‐reviewed studies and reports to ...
Fredrick Juma Syanya, Zachariy Oreko Winam, Paul Maina Mwangi, Harikrishnan Mahadevan, A. R. Nikhila Khanna, Mujeeb Rahiman K M, Megha Lovejan   +6 more
wiley   +1 more source

Impact of mutations affecting 4′-fluorouridine susceptibility on fitness and treatment outcomes for Venezuelan equine encephalitis virus

Journal of Virology
Venezuelan equine encephalitis virus (VEEV) is a prototypical encephalitic alphavirus. Members of the Alphavirus genus are found across the globe, transmitted by arthropod vectors, and cause significant disease burdens in humans and animals.
Jenny Wong, Tahirah Moore, Devin Lewis, Carolin M. Lieber, Dariia Vyshenska, Elizabeth B. Sobolik, Sarah Zimmermann, George R. Painter, Richard K. Plemper, Alexander L. Greninger, Robert M. Cox   +10 more
doaj   +1 more source

Rational Design of Broad‐Spectrum Anti‐Enteroviral Molecular Glues Targeting Enteroviral RNAi Suppressors

Advanced Science, Volume 13, Issue 38, 9 July 2026.
By leveraging this homodimerization mechanism, molecular glues were rationally designed to induce dysfunctional 3A dimerization, thereby restoring antiviral RNAi. The optimal molecular glue, VTP‐32, demonstrated potent and pan‐enterovirus (groups A, B, D) antiviral effects.
Yuan Fang, Xiong Xie, Huidi Fan, Botao Wu, An Wang, Wenhao Dai, Zezhong Liu, Jian Li, Huoyan Tong, Jianan Li, Yujie Ren, Jinlin Wang, Xi Zhou, Hong Liu   +13 more
wiley   +1 more source

Alphavirus structure

, 2023
An illustration of the structure of an alphavirus, including structural proteins. Created by me in Illustrator.
Robert Lawrence (17410479)
core   +1 more source