Results 81 to 90 of about 9,810 (173)

Zoonotic Alphaviruses in Fatal and Neurologic Infections in Wildlife and Nonequine Domestic Animals, South Africa

Emerging Infectious Diseases, 2020
Alphaviruses from Africa, such as Middelburg virus (MIDV), and Sindbis virus (SINV), were detected in horses with neurologic disease in South Africa, but their host ranges remain unknown.
Jumari Steyn, Isabel Fourie, Johan Steyl, June Williams, Voula Stivaktas, Elizabeth Botha, Stefanie van Niekerk, Bjorn Reininghaus, Marietjie Venter   +8 more
doaj   +1 more source

Serologic Surveillance for Orthoflaviviruses and Chikungunya Virus in Bats and Opossums in Chiapas, Mexico

Viruses
We performed serologic surveillance for selected arthropod-borne viruses (arboviruses) in bats and opossums in the Lacandona Rainforest, Chiapas, Mexico, in 2023–2024.
J. Manuel Aranda-Coello, Carlos Machain-Williams, Manuel Weber, Alma R. Dzul Rosado, Tyler R. Simpkins, Bradley J. Blitvich   +5 more
doaj   +1 more source

Chronic alphavirus infection of L cells.

Acta virologica, 1981
Chronic infection of L cells with Sindbis virus, induced in the absence of antiviral antibody, was studied by virological methods in combination with light and electron microscopy. Both Sindbis virus and endogenous oncovirus antigens were revealed in the cells by immunofluorescence.
T A, Ivannikova, , Karmysheva VYa, N V, Ovsyannikova, L M, Farutina   +3 more
openaire   +1 more source

TRIM32 inhibits Venezuelan equine encephalitis virus infection by targeting a late step in viral entry.

PLoS Pathogens
Alphaviruses are mosquito borne RNA viruses that are a reemerging public health threat. Alphaviruses have a broad host range, and can cause diverse disease outcomes like arthritis, and encephalitis.
Yifan Xie, Jie Cao, Shuyi Gan, Lingdong Xu, Dongjie Zhang, Suhong Qian, Feng Xu, Qiang Ding, John W Schoggins, Wenchun Fan   +9 more
doaj   +1 more source

Translational Control of Alphavirus–Host Interactions: Implications in Viral Evolution, Tropism and Antiviral Response

Viruses
Alphaviruses can replicate in arthropods and in many vertebrate species including humankind, but only in vertebrate cells do infections with these viruses result in a strong inhibition of host translation and transcription.
Iván Ventoso, Juan José Berlanga, René Toribio, Irene Díaz-López   +3 more
doaj   +1 more source

[Morphological study of a mixed alphavirus infection].

Voprosy virusologii, 1982
In combined paired cultivation of 8 Venezuelan equine encephalomyelitis virus, multiploid virions formed in 17.8% of cases. Five clones with this effect were used in mixed infections with clones of Semliki Forest and Sindbis viruses. In these infections changes in virions of the virus progeny were observed in 20% and 16.6%, respectively.
B V, Gushchin, Ia Ia, Tsilinskiĭ, E F, Karpova, E A, Gushchina, S M, Klimenko   +4 more
openaire   +1 more source

Endemic and Epidemic Human Alphavirus Infections in Eastern Panama: An Analysis of Population-Based Cross-Sectional Surveys. [PDF]

Am J Trop Med Hyg, 2020
Carrera JP, Cucunubá ZM, Neira K, Lambert B, Pittí Y, Liscano J, Garzón JL, Beltran D, Collado-Mariscal L, Saenz L, Sosa N, Rodriguez-Guzman LD, González P, Lescano AG, Pereyra-Elías R, Valderrama A, Weaver SC, Vittor AY, Armién B, Pascale JM, Donnelly CA.   +20 more
europepmc   +1 more source

Venezuelan equine encephalitis virus non-structural protein 3 dictates superinfection exclusion in mammalian cells

npj Viruses
Superinfection exclusion (SIE) prevents secondary infections of already infected cells. Arthritogenic alphaviruses induce SIE via early proteolytical cleavage of replicase precursor by non-structural protein 2 (nsP2).
Tessy A. H. Hick, Taja Zotler, Davita Bosveld, Corinne Geertsema, Monique M. van Oers, Gorben P. Pijlman   +5 more
doaj   +1 more source

Unraveling the complex interplay: immunopathology and immune evasion strategies of alphaviruses with emphasis on neurological implications

Frontiers in Cellular and Infection Microbiology
Arthritogenic alphaviruses pose a significant public health concern due to their ability to cause joint inflammation, with emerging evidence of potential neurological consequences.
Raquel de Oliveira Souza, José Wandilson Barboza Duarte Júnior, Victória Simões Della Casa, Daniela Santoro Rosa, Laurent Renia, Laurent Renia, Laurent Renia, Carla Claser, Carla Claser   +8 more
doaj   +1 more source

The Role of the Deubiquitylase MYSM1 During Alphavirus Infection [PDF]

, 2018
The Role of the Deubiquitylase MYSM1 During Alphavirus Infection Amer Nubgan The members of the genus Alphavirus are positive-sense RNA viruses and it is one of two within the family Togaviridae. Most alphaviruses are predominantly transmitted to susceptible vertebrates by a mosquito vector.
openaire   +1 more source