Results 81 to 90 of about 10,340 (193)

Oncolytic Therapy: Delivery System and New Therapeutic Strategies for Cancer

MedComm, Volume 7, Issue 4, April 2026.
This review summarizes recent advances in nanoparticle‐ and cell‐mediated OVs delivery strategies that improve biodistribution and tumor targeting while limiting immune clearance. It also examines combination approaches that enhance therapeutic efficacy through tumor microenvironment modulation or immune activation, thereby overcoming immunosuppression
Sikan Jin, Yi Zhang, Ziling Zhou, Yaqi Zhang, Ting Yu, Rui Xu, Lin Xu, Jidong Zhang, Longze Zhang, Shan Yang, Xianyao Wang   +10 more
wiley   +1 more source

Variable effects of Wolbachia on alphavirus infection in Aedes aegypti

, 2023
2. Abstract Wolbachia pipientis (= Wolbachia ) has promise as a tool to suppress virus transmission by Aedes aegypti mosquitoes.
Brittany L. Dodson, Sujit Pujhari, Marco Brustolin, Hillery C. Metz, Jason L. Rasgon   +4 more
openaire   +2 more sources

Pathogenesis of experimental salmonid alphavirus infection in vivo: an ultrastructural insight [PDF]

Veterinary Research, 2016
Salmonid alphavirus (SAV) is an enveloped, single-stranded, positive sense RNA virus belonging to the family Togaviridae. It causes economically devastating disease in cultured salmonids. The characteristic features of SAV infection include severe histopathological changes in the heart, pancreas and skeletal muscles of diseased fish.
Herath, Tharangani, Ferguson, Hugh, Weidmann, Manfred, Bron, James, Thompson, Kim D, Adams, Alexandra, Muir, Katherine, Richards, Randolph   +7 more
openaire   +5 more sources

Antivirals Targeting Coronavirus RNA‐Dependent RNA Polymerase and Main Protease: From Mechanisms of Action to Outcomes in COVID‐19 Clinical Trials

Microbial Biotechnology, Volume 19, Issue 4, April 2026.
The target sites of COVID‐19 antivirals discussed in the present opinion paper, namely the RNA dependent RNA polymerase Nsp12 and of the main viral protease Nsp5, are indicated by a red star in the overview of the replication cycle of coronavirus SARS‐CoV‐2.
Harald Brüssow
wiley   +1 more source

Hunting in the Rainforest and Mayaro Virus Infection: An emerging Alphavirus in Ecuador

Journal of Global Infectious Diseases, 2011
Objectives: The objectives of this report were to document the potential presence of Mayaro virus infection in Ecuador and to examine potential risk factors for Mayaro virus infection among the personnel of a military garrison in the Amazonian rainforest.
Ricardo O Izurieta, Maurizio Macaluso, Douglas M Watts, Robert B Tesh, Bolivar Guerra, Ligia M Cruz, Sagar Galwankar, Sten H Vermund   +7 more
openaire   +3 more sources

Imatinib Mesylate as an Effective Anti-viral Treatment for Alphavirus Infections

, 2017
Alphaviruses are plus-strand RNA viruses that are transmitted by mosquitoes. There are very limited vaccines and treatment options available to those infected with alphaviruses, resulting in significant human and animal morbidity and
Krow, Erika S., Steele, J. Jordan, Costlow, Jessica L.   +2 more
core   +1 more source

Alphavirus-host interactions : how to unravel the proviral activity of G3BP

, 2019
The genus Alphavirus belongs to the virus family Togaviridiae, a group of arthropod-borne enveloped RNA viruses with single-stranded, positive-sense genome.
Benjamin Götte (18672085)
core  

Development of eNA Sampling for Early Detection of Pathogens in On‐Farm Water Sources

Environmental DNA, Volume 8, Issue 2, March/April 2026.
We compare four water‐sampling methods for detecting microbial and viral eNA in livestock troughs and show all approaches effectively recover community profiles, supporting flexible, field‐ready surveillance of livestock pathogens. ABSTRACT Early detection of livestock pathogens is critical for mitigating risk and implementing timely control or ...
Maxine P. Piggott, Allyson Malpartida
wiley   +1 more source

CHIKUNGUNYA VIRUS: WHAT DO WE KNOW ABOUT THIS ARBOVIRUS INFECTION? (IN SPANISH)

Revista Ciencias Biomédicas, 2014
Introduction: for Colombia the arrival of the Chikungunya virus (CHIKV) constitutes a potential problem of public health due to in the country as much in rural as urban areas, the presence of the A.
Ochoa-Díaz Margarita María, De León-Benito Revollo Yéssika, Rodríguez-Quintero Gerson, Gómez-Camargo Doris Esther   +3 more
doaj  

Borna disease virus infection: Retrospective case series of five horses and two donkeys in Switzerland

Equine Veterinary Education, Volume 38, Issue 3, Page e119-e129, March 2026.
Summary Borna disease is an acute to subacute, rarely chronic non‐purulent meningoencephaylomyelitis affecting mainly horses and sheep. This case series describes the clinical signs, diagnosis, treatment, outcome and post‐mortem findings of five horses and two donkeys with this condition. The equids affected were geldings or mares of various breeds and
I. L. Piotrowski, M. Hilbe, H. K. Junge
wiley   +1 more source