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Alphavirus Infection of the CNS: Entry, Dissemination, and Neurodegeneration
Alphaviruses most often associated with neuroinvasive disease are limited to the Americas and include strains of EEEV, VEEV, and WEEV. The process of alphavirus entry into the CNS of infected vertebrates following challenge is not well-understood. It is thought that virus entry into the CNS depends on the inoculation route.
Phillips AT +3 more
openaire +1 more source
We performed serologic surveillance for selected arthropod-borne viruses (arboviruses) in bats and opossums in the Lacandona Rainforest, Chiapas, Mexico, in 2023–2024.
J. Manuel Aranda-Coello +5 more
doaj +1 more source
Chronic alphavirus infection of L cells.
Chronic infection of L cells with Sindbis virus, induced in the absence of antiviral antibody, was studied by virological methods in combination with light and electron microscopy. Both Sindbis virus and endogenous oncovirus antigens were revealed in the cells by immunofluorescence.
T A, Ivannikova +3 more
openaire +1 more source
Host-pathogen interactions during alphavirus infection
Arthritogenic alphavirus infection causes debilitating pain in the joints and muscles with many patients experiencing such symptoms chronically. However, there is insufficient evidence to explain the underlying causes behind symptoms of persistent ...
Lim, Elisa X
core +1 more source
Induction of programmed cell death in mammalian cells by isolates of Ross River virus [PDF]
Arthritogenic alphaviruses, such as Ross River virus (RRV) are associated with worldwide outbreaks of human polyarthritis/arthralgia. The pathogenesis of RRV and other alphaviruses is poorly understood.
Back, Chelsea
core
Alphaviruses are mosquito borne RNA viruses that are a reemerging public health threat. Alphaviruses have a broad host range, and can cause diverse disease outcomes like arthritis, and encephalitis.
Yifan Xie +9 more
doaj +1 more source
Alphaviruses can replicate in arthropods and in many vertebrate species including humankind, but only in vertebrate cells do infections with these viruses result in a strong inhibition of host translation and transcription.
Iván Ventoso +3 more
doaj +1 more source
Annual; Began with Oct. 1, 2008.; Description based on: Oct. 1, 2008; tilte from PDF cover (publisher's web site, viewed May 21, 2009).; At head of title: State of Connecticut.; "An Act Concerning Hospital Acquired Infections."; Latest issue consulted ...
Healthcare Associated Infections Program (Conn.)
core +1 more source
[Morphological study of a mixed alphavirus infection].
In combined paired cultivation of 8 Venezuelan equine encephalomyelitis virus, multiploid virions formed in 17.8% of cases. Five clones with this effect were used in mixed infections with clones of Semliki Forest and Sindbis viruses. In these infections changes in virions of the virus progeny were observed in 20% and 16.6%, respectively.
B V, Gushchin +4 more
openaire +1 more source
Superinfection exclusion (SIE) prevents secondary infections of already infected cells. Arthritogenic alphaviruses induce SIE via early proteolytical cleavage of replicase precursor by non-structural protein 2 (nsP2).
Tessy A. H. Hick +5 more
doaj +1 more source

