Results 71 to 80 of about 16,448 (221)

Coat colour phenotype of Qingyu pig is associated with polymorphisms of melanocortin receptor 1 gene [PDF]

Asian-Australasian Journal of Animal Sciences, 2017
Objective Qingyu pig, a Chinese indigenous pig breed, exhibits two types of coat colour phenotypes, including pure black and white with black spotting respectively.
Xiaoqian Wu, Zhendong Tan, Linyuan Shen, Qiong Yang, Xiao Cheng, Kun Liao, Lin Bai, Surong Shuai, Mingzhou Li, Xuewei Li, Shunhua Zhang, Li Zhu   +11 more
doaj   +1 more source

Pharmacogenetics of analgesic drugs [PDF]

, 2013
• Individual variability in pain perception and differences in the efficacy of analgesic drugs are complex phenomena and are partly genetically predetermined.
Branford, R, Cregg, R, Gubbay, A, Russo, G, Sato, H   +4 more
core   +1 more source

Germline MC1R Variants and BRAF Mutant Melanoma [PDF]

Journal of Investigative Dermatology, 2008
Recent studies have demonstrated that melanocortin-1 receptor (MC1R) variants increase the risk of melanomas harboring BRAF mutations. This finding provides insight into the relationship between host genotype and selection for somatic mutation type. Additional larger studies are required in diverse populations to further examine the interaction between
Hacker, Elke, Hayward, Nicholas K.
openaire   +1 more source

Comparative Molecular Insights into Developmental and Behavioral Toxicity Induced by Octocrylene and Ethylhexyl Salicylate Exposure on Zebrafish

Integrative Zoology, EarlyView.
This study compared the ecological toxicity of organic ultraviolet filters, octocrylene (OC) and ethylhexyl salicylate (EHS), on zebrafish embryos and larvae. EHS exhibited higher acute toxicity, causing increased mortality, hypoactive behavior at 50 mg/L, and disruptions in lipid homeostasis, while OC primarily affected hypoxia response and ...
Xiaoyang Lu, Li Sun, Jiao Chen, Jing Wang, Miao Guan, Shixia Xu   +5 more
wiley   +1 more source

Variability of the mc1r gene in melanic and non-melanic Podarcis lilfordi and Podarcis pityusensis from the Balearic archipelago.

PLoS ONE, 2013
The association between polymorphism at the mc1r locus and colour variation was studied in two wall lizard species (Podarcis lilfordi and P. pityusensis) from the Balearic archipelago.
Joana M Buades, Virginia Rodríguez, Bàrbara Terrasa, Valentin Pérez-Mellado, Richard P Brown, Jose A Castro, Antònia Picornell, M M Ramon   +7 more
doaj   +1 more source

Diversity across major and candidate genes in European local pig breeds [PDF]

, 2018
The aim of this work was to analyse the distribution of causal and candidate mutations associated to relevant productive traits in twenty local European pig breeds.
Alves, E., Araujo, J.P., Bozzi, R., Candek-Potokar, M., Charneca, R., Crovetti, J., Djurkin-Kusec, I., Estellé, J., Fernandéz, A.I., Fontanesi, L., Gallo, M., García, F., García-Casco, J., Geraci, C., Karolyi, D., Kusec, G., Martins, J.M., Mercat, M.J., Muñoz, M., Núñez, Y., Quintanilla, R., Radovic, C., Razmaite, V., Riquet, J., Savic, R., Skrlep, M., Tibau, J., Zimmer, C., Óvilo, C.   +28 more
core   +1 more source

Age‐specific melanoma risk associated with nevi: a pooled analysis from the M‐SKIP project

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Objective This study investigates the association of melanoma risk with total‐body nevus count and the presence of atypical nevi in younger (< 40 years) and older (> 60 years) individuals. Methods A pooled analysis was conducted within the M‐SKIP project, based on multiple melanoma case‐control studies.
Giulia Doi, Aurora Gaeta, Simone Ribero, Nelleke Gruis, Julia Newton‐Bishop, David Polsky, DeAnn Lazovich, Paola Ghiorzo, Gloria Ribas, Chiara Menin, Alexander J. Stratigos, Gabriella Guida, Susana Puig, Maria Concetta Fargnoli, Peter A. Kanetsky, Paola Queirolo, Vincenzo Bagnardi, Veronique Bataille, Sara Raimondi, Sara Gandini, M‐SKIP study group   +20 more
wiley   +1 more source

Genetic determinants of freckle occurrence in the Spanish population: Towards ephelides prediction from human DNA samples [PDF]

, 2018
Prediction of human pigmentation traits, one of the most differentiable externally visible characteristics among individuals, from biological samples represents a useful tool in the field of forensic DNA phenotyping.
Deserio Cuesta, Julio Alberto, Hernando, Barbara, Ibáñez Gual, Maria Victoria, Martinez-Cadenas, Conrado, Soria Navarro, Raquel, Vilar Sastre, Inca   +5 more
core   +1 more source

Environmental correlates of spatio‐temporal patterns of colour variation in a bird of prey: The common buzzard (Buteo buteo)

Ibis, EarlyView.
High colour variability in animals has been associated with adaptability to environmental change. Establishing how such variability is distributed in time and space, and identifying environmental correlates, can help understand the processes driving it.
Kaspar Delhey, Elena F. Kappers, Mihai Valcu, Christiaan Both, Bart Kempenaers   +4 more
wiley   +1 more source

Activation of the melanocortin-1 receptor attenuates neuronal apoptosis after traumatic brain injury by upregulating Merlin expression

Brain Research Bulletin
Traumatic brain injury (TBI) is a common disease worldwide with high mortality and disability rates. Besides the primary mechanical injury, the secondary injury associated with TBI can also induce numerous pathological changes, such as brain edema, nerve
Jinqi Lu, Jin Wang, Haibo Ni, Bing Li, Jingjing Yang, Jie Zhu, Jie Qian, Rong Gao, Rong Xu   +8 more
doaj   +1 more source