Results 81 to 90 of about 9,263 (182)

Interaction between the melanocortin 1 receptor (MC1R) and agouti signalling protein genes (ASIP), and their association with black and brown coat colour phenotypes in peruvian alpaca

Italian Journal of Animal Science, 2020
The aim of this work was to assess the interaction between MC1R and ASIP genes in determining coat colour variation in black and brown Peruvian alpacas. Skin biopsies were collected from 25 black alpacas and 15 brown alpacas.
Stefano Pallotti, Bathrachalam Chandramohan, Dario Pediconi, Cristina Nocelli, Antonietta La Terza, Carlo Renieri   +5 more
doaj   +1 more source

Polymorphisms in the Melanocortin-1 Receptor (Mc1R) Gene in Vitiligo

Balkan Medical Journal, 2012
Objective: Vitiligo is a progressive skin pigmentation disorder, which may be acquired or hereditary, frequently seen, and may influence every age group. The melanocortin 1 receptor (MC1R) gene is a major determinant of human pigmentation. In our study, polymorphic differences of the MC1R gene at the DNA level has been investigated in patients with ...
ACAR, Eylem, BOZKURT, Gökay, GÖRGÜLÜ, Adnan   +2 more
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Sequence Variation of Melanocortin 1 Receptor (MC1R) Gene and Association with Plumage Color in Domestic Geese

The Journal of Poultry Science, 2014
In contrast to other domestic and wild animals, the genetic variation of MC1R gene and association with plumage color has not been investigated in domestic goose.
Jing Huang, Bing Zhou, Da-Qian He, Shi-Yi Chen, Qing Zhu, Yong-Gang Yao, Yi-Ping Liu   +6 more
doaj   +1 more source

Identification of MC1R SNPs and their Association with Plumage Colors in Asian Duck

The Journal of Poultry Science, 2017
The melanocortin 1 receptor (MC1R) gene is a candidate functional gene that controls the pigment production in melanocytes. The aim of this study was to identify polymorphisms and investigate the effect of the MC1R gene on plumage coloration in duck ...
Hasina Sultana, Dong-Won Seo, Hee-Bok Park, Nu-Ri Choi, Md. Rashedul Hoque, Md. Shamsul Alam Bhuiyan, Kang-Nyeong Heo, Seung-Hwan Lee, Jun-Heon Lee   +8 more
doaj   +1 more source

NDP-MSH rescues LPS-induced neuroinflammation, synaptic deficits, and depressive-like behaviors in mice: involvement of MC1R–cAMP/PKA signaling

Frontiers in Pharmacology
IntroductionInflammatory processes contribute significantly to the pathophysiology of depression. Although the melanocortin system is well known to regulate inflammation, the specific contribution of melanocortin 1 receptor (MC1R) and its endogenous ...
Shanglan Qu, Shanglan Qu, Xin Peng, Jieyu Ji, Ershu He, Le Jiang, Le Jiang, Ruixue Ma, Hanwei Li, Yanjiao Li, Lijuan Li, Hui-Yin Yow, Sharina Hamzah, Zhiting Gong   +13 more
doaj   +1 more source

Association Analysis of Polymorphisms in BIN1, MC1R, STARD6 and PVRL2 with Mild Cognitive Impairment in Elderly Carrying APOE ϵ4 Allele

Neuropsychiatric Disease and Treatment, 2021
Yue Wu,1,* Jiajun Yin,2,* Bixiu Yang,3 Li Tang,4 Wei Feng,5 Xiaowei Liu,1 Xingfu Zhao,1 Zaohuo Cheng1 1Department of Geriatric Psychiatry, The Affiliated Wuxi Mental Health Center with Nanjing Medical University, Wuxi, Jiangsu Province, People’s ...
Wu Y, Yin J, Yang B, Tang L, Feng W, Liu X, Zhao X, Cheng Z   +7 more
doaj  

The Role of MC1R in Speciation & Phylogeny

The American Biology Teacher, 2013
A point mutation in the MC1R gene, a G-protein-coupled receptor, has been found that could have led to the formation of two subspecies of Solomon Island flycatcher from a single ancestral population. I discuss the many roles that G-protein-coupled receptors play in vertebrate physiology and how one particular point mutation can have enormous ...
openaire   +1 more source

Is the MC1R variant p.R160W associated with Parkinson's? [PDF]

Annals of Neurology, 2015
Lubbe, Steven J, Escott-Price, Valentina, Williams, Nigel M, Morris, Huw R, Consortium, International Parkinson's Disease Genomics, Brice, Alexis, Gasser, Thomas, Hardy, John, Heutink, Peter, Sharma, Manu, Wood, Nicholas W, Nalls, Mike, Singleton, Andrew B   +12 more
openaire   +3 more sources

MC1R Gene [PDF]

, 2020
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Role of Mc1r in UV-Induced Melanoma in Animal Models

Journal of Carcinogenesis & Mutagenesis, 2014
The role of UV and pigmentation are very difficult to control for in human studies, and mechanisms difficult to infer based on statistical association with melanoma. The animal models are not representative of the human situation. But on the other hand, animal studies can be useful for basic studies that will ultimately help in building up a picture of
openaire   +2 more sources