Results 81 to 90 of about 11,568 (220)
JEADV Clinical Practice, Volume 5, Issue 2, Page 433-457, June 2026.ABSTRACT Background As solid organ transplantation becomes more prevalent, more patients are living on long‐term immunosuppression, greatly increasing the risk of cutaneous squamous cell carcinoma (cSCC). Although significant improvements have been achieved in the treatment of cSCC, further studies are needed to identify the specific protein expression
William Murray +8 more
wiley +1 more source
Crucial role of the melanocortin receptor MC1R in experimental colitis [PDF]
Gut, 2006 Background and aims: α-Melanocyte stimulating hormone (αMSH) is known to exert anti-inflammatory effects, for example in murine DSS (dextran sodium sulphate induced) colitis. The anti-inflammatory functions of αMSH are mediated by the melanocortin1-receptor (MC1R) in an autoregulatory loop.
C, Maaser +7 more
openaire +2 more sources
Melanogenic effect of dersimelagon (MT‐7117), a novel oral melanocortin 1 receptor agonist
Skin Health and Disease, 2022 Background The activation of melanocortin 1 receptor (MC1R) on melanocytes stimulates the production of eumelanin. A tridecapeptide α melanocyte‐stimulating hormone (αMSH) is known to induce skin pigmentation.
T. Suzuki +12 more
doaj +1 more source
Evolutionary Applications, Volume 19, Issue 6, June 2026.ABSTRACT Horses are major domestic animals and cultural symbols that have accompanied humans for millennia. They underpin transport, agriculture, warfare and sport, and also provide a model for studying domestication, complex traits and adaptive evolution.
Ying Lu +6 more
wiley +1 more source
Analysis of Genetic Basis of the Red Coat Colour of Crossbred of Duroc and Ding'an Pig
Guangdong nongye kexue【Objective】The melanocortin 1 receptor (MC1R) plays a critical role in mammalian pigmentation and coat color formation. Different MC1R alleles are associated with various coat color patterns in pigs.
Sitong ZHU +6 more
doaj +1 more source
The Journal of Poultry Science, 2019 The Japanese quail expresses polymorphism in plumage colors, including black, yellow, white, wild-type (maroon), and various intermediate colors through hybridization of quail with different plumage colors.
Yi-xin Li +4 more
doaj +1 more source
Do Alopecia Areata and Hair Colour Have a Shared Genetic Component?
Experimental Dermatology, Volume 35, Issue 6, June 2026.The aim of our study was to determine whether hair colour and the risk of developing alopecia areata (AA) share a genetic basis. While we found no evidence for a broadly shared polygenic background, our analyses revealed suggestive evidence that genetically predicted blond hair is associated with a reduced risk of AA. ABSTRACT Alopecia areata (AA) is a
Leonie Rieger‐Molitor +9 more
wiley +1 more source
Mouse MC1R siRNA duplex sequences.
, 2013 Mouse MC1R siRNA duplex sequences.
Xiang-rong Dai (282203) +16 more
core +1 more source
Advanced Healthcare Materials, Volume 15, Issue 20, 27 May 2026.Pressure skin wounds are frequent complications after spinal cord injury (SCI), with impaired healing due to vascular and immune deficits. Elastin‐like polypeptides (ELP) fused to α‐MSH (MSH‐ELP) or MCP‐1 (MCP‐ELP) are developed and tested on these wounds. The resulting nanoparticles are non‐toxic and bioactive, and they enhance macrophage recruitment,
Suneel Kumar +7 more
wiley +1 more source
Frontiers in ImmunologyBackground and objectiveThis study aims to explore the relationship between melanocortin-1 receptor (MC1R) expression levels and clinical pathological parameters of melanoma, as well as its potential as a prognostic biomarker.MethodsThis retrospective ...
Tian Xiang +4 more
doaj +1 more source