Results 21 to 30 of about 5,865,115 (353)
Aberrant N-glycolylneuraminic acid in breast MCF-7 cancer cells and cancer stem cells
Frontiers in Molecular Biosciences, 2022 N-Glycolylneuraminic acid (Neu5Gc) is not normally detected in humans because humans lack the hydroxylase enzyme that converts cytidine-5′-monophosphate-N-acetylneuraminic acid (CMP-Neu5Ac) to CMP-Neu5Gc; thus, any Neu5Gc appearing in the human body is ...
Wenqian Yang +4 more
doaj +1 more source
Role of insulin-like growth factor binding protein-3 in 1, 25-dihydroxyvitamin-d 3 -induced breast cancer cell apoptosis. [PDF]
, 2013 Insulin-like growth factor I (IGF-I) is implicated in breast cancer development and 1, 25-dihydroxyvitamin D3 (1, 25-D3) has been shown to attenuate prosurvival effects of IGF-I on breast cancer cells.
Brosseau, C, Colston, KW, Pirianov, G
core +2 more sources
New 3-Cyano-2-Substituted Pyridines Induce Apoptosis in MCF 7 Breast Cancer Cells
Molecules, 2016 The synthesis of new 3-cyano-2-substituted pyridines bearing various pharmacophores and functionalities at position 2 is described. The synthesized compounds were evaluated for their in vitro anti-cancer activities on five cancer cell lines using 5-FU as
Ahmed Malki +7 more
doaj +1 more source
Frontiers in Pharmacology, 2021 Objective: C49 is a chalcone derivative. The aim of the current study is to illuminate the efficacy of C49 in reversing multidrug resistance (MDR) in MCF-7/DOX cells and its underlying molecular mechanism.Methods: The cytotoxic effects of C49 on MCF-7 ...
Ting Wang +7 more
doaj +1 more source
Lewis X antigen mediates adhesion of human breast carcinoma cells to activated endothelium. Possible involvement of the endothelial scavenger receptor C-Type lectin [PDF]
, 2007 Lewis x (Lex, CD15), also known as SSEA-1 (stage specific embryonic antigen-1), is a trisaccharide with the structure Galβ(1–4)Fucα(1–3)GlcNAc, which is expressed on glycoconjugates in human polymorphonuclear granulocytes and various tumors such as colon
A Hittelet +51 more
core +1 more source
Cell Communication and Signaling, 2017 There is compelling evidence associating senescent cells with the malignant progression of tumours. Of all senescence-related mechanisms, the so-called senescence-associated secretory phenotype (SASP) has attracted much attention.
Paola Ortíz-Montero +2 more
semanticscholar +1 more source
Expression and Functional of LncRNA XIST in MCF-7 Breast Cancer Cells
Zhongliu Fangzhi Yanjiu, 2019 Objective To investigate the expression and function of lncRNA XIST in MCF-7 breast cancer cells. Methods The expression of XIST in MCF 10A human normal breast epithelial cells and MCF-7 human breast cancer cells were detected by qRT-PCR.
HOU Xia +10 more
doaj +1 more source
International Journal of Nanomedicine, 2018 Introduction Silver nanoparticles (AgNPs) are of great interest due to their unique and controllable characteristics. Different synthesis methods have been proposed to produce these nanoparticles, which often require elevated temperatures/pressures or ...
Sadegh Khorrami +4 more
semanticscholar +1 more source
Effects of Quercetin-Loaded Nanoparticles on MCF-7 Human Breast Cancer Cells
Medicina, 2019 Background and objectives: Previous studies have shown anti-tumor activity of quercetin (QT). However, the low bioavailability of QT has restricted its use.
F. Niazvand +5 more
semanticscholar +1 more source
Molecules, 2016 Despite progressive research being done on drug therapy to treat breast cancer, the number of patients succumbing to the disease is still a major issue. Combinatorial treatment using different drugs and herbs to treat cancer patients is of major interest
Muhammad Yusran Abdul Aziz +9 more
doaj +1 more source