Results 31 to 40 of about 5,896,577 (400)

Senescence-associated IL-6 and IL-8 cytokines induce a self- and cross-reinforced senescence/inflammatory milieu strengthening tumorigenic capabilities in the MCF-7 breast cancer cell line

Cell Communication and Signaling, 2017
There is compelling evidence associating senescent cells with the malignant progression of tumours. Of all senescence-related mechanisms, the so-called senescence-associated secretory phenotype (SASP) has attracted much attention.
Paola Ortíz-Montero, A. Londoño-Vallejo, J. Vernot   +2 more
semanticscholar   +1 more source

Lewis X antigen mediates adhesion of human breast carcinoma cells to activated endothelium. Possible involvement of the endothelial scavenger receptor C-Type lectin [PDF]

, 2007
Lewis x (Lex, CD15), also known as SSEA-1 (stage specific embryonic antigen-1), is a trisaccharide with the structure Galβ(1–4)Fucα(1–3)GlcNAc, which is expressed on glycoconjugates in human polymorphonuclear granulocytes and various tumors such as colon
A Hittelet, AM Roon van, C Ballaré, D Vestweber, DS Johnston, E Spooncer, EA Jaffé, ED Ball, EG Rizzatti, F Sánchez-Madrid, HC Gooi, HD Soule, IHN Wong, J Kitayama, J Mitoma, J Mordoh, J Mordoh, J-W Liao, JF Harris, JI Yamashita, JL Magnani, José Mordoh, JP Buyon, K Drbal, KL Allendoerfer, KM Skubitz, KM Skubitz, KP Gisbergen van, Kurt Drickamer, L Lucka, M Albrechtsen, M Capurro, M Capurro, M-L Majuri, Mariana Isabel Capurro, María Marcela Barrio, María Teresa Elola, Maureen E. Taylor, MK Robinson, ML Phillips, MM Burdick, N Kawamura, O Ohana-Malka, Peter J. Coombs, PJ Coombs, R Giavazzi, R Kannagi, S D´Costa, S Hakomori, SC Stocks, T Bild, TB Geijtenbeek   +51 more
core   +1 more source

New 3-Cyano-2-Substituted Pyridines Induce Apoptosis in MCF 7 Breast Cancer Cells

Molecules, 2016
The synthesis of new 3-cyano-2-substituted pyridines bearing various pharmacophores and functionalities at position 2 is described. The synthesized compounds were evaluated for their in vitro anti-cancer activities on five cancer cell lines using 5-FU as
Ahmed Malki, Mona Mohsen, Hassan Aziz, Ola Rizk, Omima Shaban, Mohamed El-Sayed, Zaki A. Sherif, Hayam Ashour   +7 more
doaj   +1 more source

Effects of Quercetin-Loaded Nanoparticles on MCF-7 Human Breast Cancer Cells

Medicina, 2019
Background and objectives: Previous studies have shown anti-tumor activity of quercetin (QT). However, the low bioavailability of QT has restricted its use.
F. Niazvand, M. Orazizadeh, L. Khorsandi, M. Abbaspour, Esrafil Mansouri, A. Khodadadi   +5 more
semanticscholar   +1 more source

Expression and Functional of LncRNA XIST in MCF-7 Breast Cancer Cells

Zhongliu Fangzhi Yanjiu, 2019
Objective To investigate the expression and function of lncRNA XIST in MCF-7 breast cancer cells. Methods The expression of XIST in MCF 10A human normal breast epithelial cells and MCF-7 human breast cancer cells were detected by qRT-PCR.
HOU Xia, ZHOU Yongan, TIAN Shuxiong, LI Chao, LI Min, REN Ruirui, HAN Yaxin, CHENG Jianping, LI Xingxing, LI Zhe, BAI Yuan   +10 more
doaj   +1 more source

Stemness marker ALDH1A1 promotes tumor angiogenesis via retinoic acid/HIF-1α/VEGF signalling in MCF-7 breast cancer cells

Journal of experimental & clinical cancer research : CR, 2018
Aldehyde dehydrogenase 1A1 (ALDH1A1), a member of aldehyde dehydrogenase family, is a marker of stemness in breast cancer. During tumor progression cancer stem cells (CSCs) have been reported to secrete angiogenic factors to orchestrate the formation of ...
Valerio Ciccone, E. Terzuoli, S. Donnini, A. Giachetti, L. Morbidelli, M. Ziche   +5 more
semanticscholar   +1 more source

Elevated expression of long intergenic non-coding RNA HOTAIR in a basal-like variant of MCF-7 breast cancer cells [PDF]

, 2014
Epigenetic regulation of gene expression is critical to phenotypic maintenance and transition of human breast cancer cells. HOX antisense intergenic RNA (HOTAIR) is a long intergenic non-coding RNA that epigenetically represses gene expression via ...
Burow, Matthew E., Cao, Subing, Collins-Burow, Bridgette, El-Dahr, Samir S., Fang, Fang, Flemington, Erik K., Jayawickramarajah, Janarthanan, Nephew, Kenneth P., Nguyen, Hong T., Rhodes, Lyndsay V., Shan, Bin, Yao, Xiao, Yu, Qiang, Zhuang, Yan, Zhuo, Ying   +14 more
core   +1 more source

Combinatorial Cytotoxic Effects of Damnacanthal and Doxorubicin against Human Breast Cancer MCF-7 Cells in Vitro

Molecules, 2016
Despite progressive research being done on drug therapy to treat breast cancer, the number of patients succumbing to the disease is still a major issue. Combinatorial treatment using different drugs and herbs to treat cancer patients is of major interest
Muhammad Yusran Abdul Aziz, Nadiah Abu, Swee Keong Yeap, Wan Yong Ho, Abdul Rahman Omar, Nor Hadiani Ismail, Syahida Ahmad, Mehdi R. Pirozyan, Nadeem M. Akhtar, Noorjahan Banu Alitheen   +9 more
doaj   +1 more source

Combination of Doxorubicin and Berberine Generated Synergistic Anticancer Effect on Breast Cancer Cells Through Down-regulation of Nanog and miRNA-21 Gene Expression

Middle East Journal of Cancer, 2020
Background: Our purpose was to investigate the effect of berberine (BER) and doxorubicin (DOX) on the expression of stem cell markers Nanog and microRNA- 21 in MCF-7 cells.
Samia A. Ebeid, Nadia A. Abd El Moneim, Hossam El-Din M. Ghoneim, Sanaa A. El-Benhawy, Samah E. Ismail   +4 more
doaj   +1 more source

A New Chalcone Derivative C49 Reverses Doxorubicin Resistance in MCF-7/DOX Cells by Inhibiting P-Glycoprotein Expression

Frontiers in Pharmacology, 2021
Objective: C49 is a chalcone derivative. The aim of the current study is to illuminate the efficacy of C49 in reversing multidrug resistance (MDR) in MCF-7/DOX cells and its underlying molecular mechanism.Methods: The cytotoxic effects of C49 on MCF-7 ...
Ting Wang, Jingjing Dong, Xu Yuan, Haotian Wen, Linguangjin Wu, Jianwen Liu, Hua Sui, Wanli Deng   +7 more
doaj   +1 more source