Physiological media and oxygen levels modulate cancer hallmarks in cultured breast cancer cells
MCF7 breast cancer cells were cultured in standard conditions (18% O2 and DMEM) and physiological conditions (5% O2 and Plasmax, a medium modeled after the human plasma metabolome). A combined transcriptomic and proteomic approach was used to identify gene expression signatures at the mRNA and protein levels upstream of functional enrichment analyses ...
Jacob E. Wiebe +5 more
wiley +1 more source
Expression pattern analysis of the MAGE family genes in breast cancer patients and hypomethylation activation in the MCF-7 cells. [PDF]
Almatrafi AM, Alamery S, Almutairi MH.
europepmc +1 more source
Are respiratory physicians adherent to guidelines when evaluating pulmonary nodules?
Abstract Introduction Although fewer than 1% of pulmonary nodules are malignant, appropriate evaluation is essential in optimising patient outcomes. The 2017 Fleischner Society Guidelines provide recommendations on management of incidentally detected nodules; however, studies to date have shown variable guideline adherence.
Laura Tu +5 more
wiley +1 more source
Correction: Dallons et al. GPR91 Receptor Mediates Protection against Doxorubicin-Induced Cardiotoxicity without Altering Its Anticancer Efficacy. An In Vitro Study on H9C2 Cardiomyoblasts and Breast Cancer-Derived MCF-7 Cells. <i>Cells</i> 2020, <i>9</i>, 2177. [PDF]
Dallons M +4 more
europepmc +1 more source
ABSTRACT Objective To evaluate the microshear bond strength (μSBS) to lithium disilicate achieved with universal adhesives (with and without silane) compared with one‐step and two‐step silanes, immediately (IM) and after thermocycling (TC). Chemical interaction (CI) was also assessed.
Camilo Pulido +4 more
wiley +1 more source
ABSTRACT Aim The aim of this Phase I/II open‐label study was to assess the safety and efficacy of NTI164, a novel full‐spectrum medicinal cannabis plant extract 0.08% Δ‐9‐tetrahydrocannabinol (THC), in Rett syndrome (RTT). Methods Eleven female participants (5–16 years) with a pathogenic variant in the MECP2 gene were recruited to this study, receiving
B. A. Keating +7 more
wiley +1 more source
Combined Effects of Polystyrene Nanosphere and Homosolate Exposures on Estrogenic End Points in MCF-7 Cells and Zebrafish. [PDF]
Ye R +14 more
europepmc +1 more source
ABSTRACT Objective Traditional biocompatibility assessments primarily address cytotoxicity and bulk material properties but often overlook molecular responses that occur below toxicity thresholds. Detecting these subtle effects is crucial for materials intended for prolonged contact with human tissues.
Katia Barbaro +7 more
wiley +1 more source
Abstract Background To maximize the utilization of cold‐stored platelets (CSPs) in preclinical research, the use of small‐volume storage bags (mini‐bags) or tubes would allow multiple treatment groups to be investigated from a single component. It is necessary to determine the effect of using downscaled storage formats on CSP quality and function ...
Janhavi Mahajan +3 more
wiley +1 more source
Anti-Menopausal Effect of Heat-Killed Bifidobacterium breve HDB7040 via Estrogen Receptor-Selective Modulation in MCF-7 Cells and Ovariectomized Rats. [PDF]
Kim HJ +6 more
europepmc +1 more source

