Results 201 to 210 of about 106,995 (260)

Physiological media and oxygen levels modulate cancer hallmarks in cultured breast cancer cells

open access: yesThe FEBS Journal, EarlyView.
MCF7 breast cancer cells were cultured in standard conditions (18% O2 and DMEM) and physiological conditions (5% O2 and Plasmax, a medium modeled after the human plasma metabolome). A combined transcriptomic and proteomic approach was used to identify gene expression signatures at the mRNA and protein levels upstream of functional enrichment analyses ...
Jacob E. Wiebe   +5 more
wiley   +1 more source

Are respiratory physicians adherent to guidelines when evaluating pulmonary nodules?

open access: yesInternal Medicine Journal, EarlyView.
Abstract Introduction Although fewer than 1% of pulmonary nodules are malignant, appropriate evaluation is essential in optimising patient outcomes. The 2017 Fleischner Society Guidelines provide recommendations on management of incidentally detected nodules; however, studies to date have shown variable guideline adherence.
Laura Tu   +5 more
wiley   +1 more source

Influence of Universal Adhesives With or Without Silane Compared to One‐Step and Two‐Step Silane Agents on Bond Strength to Lithium Disilicate

open access: yesJournal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objective To evaluate the microshear bond strength (μSBS) to lithium disilicate achieved with universal adhesives (with and without silane) compared with one‐step and two‐step silanes, immediately (IM) and after thermocycling (TC). Chemical interaction (CI) was also assessed.
Camilo Pulido   +4 more
wiley   +1 more source

Full‐Spectrum Medicinal Cannabis Plant Extract 0.08% THC (NTI164) Improves Symptoms of Rett Syndrome: An Open‐Label Study

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim The aim of this Phase I/II open‐label study was to assess the safety and efficacy of NTI164, a novel full‐spectrum medicinal cannabis plant extract 0.08% Δ‐9‐tetrahydrocannabinol (THC), in Rett syndrome (RTT). Methods Eleven female participants (5–16 years) with a pathogenic variant in the MECP2 gene were recruited to this study, receiving
B. A. Keating   +7 more
wiley   +1 more source

Combined Effects of Polystyrene Nanosphere and Homosolate Exposures on Estrogenic End Points in MCF-7 Cells and Zebrafish. [PDF]

open access: yesEnviron Health Perspect
Ye R   +14 more
europepmc   +1 more source

A Dual Cell‐Line Molecular Platform to Assess Sub‐Threshold Biocompatibility: Application to Processed Orthodontic Clears Aligners

open access: yesOrthodontics &Craniofacial Research, EarlyView.
ABSTRACT Objective Traditional biocompatibility assessments primarily address cytotoxicity and bulk material properties but often overlook molecular responses that occur below toxicity thresholds. Detecting these subtle effects is crucial for materials intended for prolonged contact with human tissues.
Katia Barbaro   +7 more
wiley   +1 more source

Downscaling to small‐volume storage bags supports platelet quality and efficient use of cold‐stored platelets for preclinical studies

open access: yesTransfusion, EarlyView.
Abstract Background To maximize the utilization of cold‐stored platelets (CSPs) in preclinical research, the use of small‐volume storage bags (mini‐bags) or tubes would allow multiple treatment groups to be investigated from a single component. It is necessary to determine the effect of using downscaled storage formats on CSP quality and function ...
Janhavi Mahajan   +3 more
wiley   +1 more source

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