Results 221 to 230 of about 106,995 (260)
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Effect of 5‐aminolevulinic acid‐mediated photodynamic therapy on MCF‐7 and MCF‐7/ADR cells
Lasers in Surgery and Medicine, 2004AbstractBackground and ObjectivesPhotodynamic therapy (PDT) has been proposed as an alternative approach in overcoming multidrug resistance (MDR) phenotype. To verify whether 5‐aminolevulinic acid (ALA)‐mediated PDT is effective in MDR cells, we studied the protoporphyrin IX (PpIX) content, intracellular localization, and phototoxicity in human breast ...
Tsuimin, Tsai +5 more
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Downregulation of SOK1 promotes the migration of MCF-7 cells
Biochemical and Biophysical Research Communications, 2011SOK1 is a member of the germinal center kinase (GCK-III) subfamily but little is known about it, particularly with respect to its role in signal transduction pathways relative to tumor metastasis. By stably transfecting SOK1 siRNA into the MCF-7 breast cancer cell line we found that SOK1 promotes the migration of MCF-7 cells, as determined using wound ...
Xu-Dong, Chen, Chien-Yu, Cho
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Actions of insulin on MCF-7 cells that are synchronized with hydroxyurea
Molecular and Cellular Endocrinology, 1987The role of insulin in stimulating metabolic processes in MCF-7 cells was studied in cells synchronized at the G1:S interphase of the cell cycle using hydroxyurea. Cells released from the hydroxyurea block progressed through one S-phase of the cell cycle when insulin was absent from the medium.
B E, Linebaugh, J A, Rillema
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Catecholestrogens are MCF-7 cell estrogen receptor agonists
The Journal of Steroid Biochemistry and Molecular Biology, 1993Catecholestrogens are important metabolites of estradiol and estrone in the human. Considerable interest has focused on the catecholestrogens 2-hydroxy- and 4-hydroxyestradiol since they bind to the estrogen receptor with an affinity in the range of estradiol.
N, Schütze +4 more
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Optimization of estrogen growth response in MCF-7 cells
In Vitro Cellular & Developmental Biology - Animal, 1992The factors involved in estradiol-17 beta induced growth stimulation of MCF-7 human breast cancer cells have been examined. Wild type MCF-7 cells (and clone E3) were shown to undergo slow growth in phenol-red-free medium containing specific calf sera. The E3 clone was used to document a mean 6-day growth stimulation of 3.35-fold (doubling time = 33 +/-
T E, Wiese +4 more
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Radiation‐induced gene expression in MCF‐7 cells
International Journal of Radiation Biology, 2003Detection of gene targets applicable to biological dosimetry and early detection of radiation-induced cell damage.MCF-7 human mammary carcinoma cells were exposed to 2 and 6 Gy X-rays. Expression of 1176 genes was traced with the Atlas Human 1.2 Array (Clontech).(1) Based on data reproducibility (about 98%), a new and improved analysis was employed. (2)
T, Stassen, M, Port, I, Nuyken, M, Abend
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Binding of progestagens to receptor proteins in MCF-7 cells
Journal of Steroid Biochemistry, 1983With the aim of finding an explanation for the biological properties of progestagens currently used for contraceptive purposes, we have assessed their specificity for progesterone, androgen and oestrogen receptors in MCF-7 cells. The specificity of progestagens for the progesterone receptors in the cytosol fraction of MCF-7 cells was similar to that ...
E W, Bergink +3 more
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Antiestrogenic Effects of LY 117018 in MCF-7 Cells
Endocrinology, 1983LY 117018 is a nonsteroidal compound which has been shown to antagonize more effectively than tamoxifen the effects of estradiol in rats and mice. We have further defined the properties of this compound on cell growth and progesterone receptor (PR) induction and have compared inhibitory effects to relative binding affinity in a human breast cancer cell
S M, Scholl, K K, Huff, M E, Lippman
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Prolidase in human breast cancer MCF-7 cells
Cancer Letters, 1998Prolidase (EC 3.4.13.9) is an ubiquitously distributed imidodipeptidase that catalyzes the hydrolysis of dipeptides containing C-terminal proline or hydroxyproline. The enzyme plays an important role in the recycling of proline for collagen synthesis and cell growth.
J A, Palka, J M, Phang
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Disruption of Mitochondrial Respiration by Melatonin in MCF-7 Cells
Toxicology and Applied Pharmacology, 2001Clinical and laboratory studies have provided evidence of oncostatic activity by the pineal neurohormone melatonin. However, these studies have not elucidated its mechanism of action. The following series of MCF-7 breast tumor cell studies conducted in the absence of exogenous steroid hormones provide evidence for a novel mechanism of oncostatic ...
A E, Scott +4 more
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