Results 61 to 70 of about 36,778 (291)
Frontiers in Microbiology, 2021 Colistin is the last resort antimicrobial for treating multidrug-resistant gram-negative bacterial infections. The plasmid-mediated colistin resistance gene, mcr-1, crucially influences colistin’s resistance transmission.
Pin-Chieh Wu +12 more
doaj +1 more source
Advanced Functional Materials, EarlyView.We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim +6 more
wiley +1 more source
Alkaline Peptone Water-Based Enrichment Method for mcr-3 From Acute Diarrheic Outpatient Gut Samples
Frontiers in Medicine, 2018 A third plasmid-mediated colistin resistance gene, mcr-3, is increasingly being reported in Enterobacteriaceae and Aeromonas spp. from animals and humans. To investigate the molecular epidemiology of mcr in the gut flora of Chinese outpatients, 152 stool
Qiaoling Sun +6 more
doaj +1 more source
Fitness cost of a mcr-1-carrying IncHI2 plasmid
PLOS ONE, 2018 IncHI2 is a common type of large mcr-1-carrying plasmids that have been found worldwide. Large plasmids could impose metabolic burden for host bacterial strains, we therefore examine the stability and fitness cost of a mcr-1-carrying 265.5-kb IncHI2 plasmid, pMCR1_1943, in Escherichia coli in nutrient-rich LB and nutrient-restricted M9 broth. Stability
Ke Ma, Yu Feng, Zhiyong Zong
openaire +4 more sources
First three Escherichia coli isolates harbouring mcr-1 in Uruguay
Journal of Global Antimicrobial Resistance, 2020 This report described the first Escherichia coli (E. coli) isolates harbouring mcr-1 in Uruguay.Three E. coli isolates were obtained from blood, urine and rectal swabs from different patients in two hospitals. Extended-spectrum β-lactamases (ESBL), plasmid-encoded (pAmpC) β-lactamases, plasmid-mediated quinolone resistance (PMQR) genes, class 1 ...
Romina Papa-Ezdra +11 more
openaire +4 more sources
Detection of mcr-1 Gene among Escherichia coli Isolates from Farmed Fish and Characterization of mcr-1 -Bearing IncP Plasmids [PDF]
Antimicrobial Agents and Chemotherapy, 2018 ABSTRACT The presence of the mcr-1 gene in Escherichia coli isolated from retail freshwater fish was investigated. Seven (3.65%) clonally unrelated original E. coli isolates from grass carp were positive for mcr-1 . The mcr-
Luchao, Lv +8 more
openaire +2 more sources
Adaptive Hydrogels With Spatiotemporal Stiffening Using pH‐Modulating Enzymes
Advanced Functional Materials, EarlyView.The chemomechanical coupling in an adaptive hydrogel is studied to further the development of adaptive hydrogels. This coupling is achieved by embedding a pH‐modulating enzyme in a pH‐responsive hydrogel. The enzymatic reaction can be triggered locally, which generates a pH‐decreasing wave throughout the system, increasing the crosslinking density and ...
Natascha Gray +3 more
wiley +1 more source
mBio, 2016 Colistin is an ultimate line of refuge against multidrug-resistant Gram-negative pathogens. Very recently, the emergence of plasmid-mediated mcr-1 colistin resistance has become a great challenge to global public health, raising the possibility that ...
Huiyan Ye +8 more
doaj +1 more source
Frontiers in Microbiology, 2023 The advent of antimicrobials-resistant (AMR), including colistin-resistant bacteria, poses a significant challenge to animal and human health, food safety, socio-economic growth, and the global environment.
Md Rezaul Karim +6 more
doaj +1 more source
Azidothymidine produces synergistic activity in combination with colistin against antibiotic-resistant Enterobacteriaceae. [PDF]
, 2019 Bacterial infections remain the leading killer worldwide which is worsened by the continuous emergence of antibiotic resistance. In particular, antibiotic-resistant Enterobacteriaceae is prevalent and extremely difficult to treat.
Coates, A, Hu, Y, Liu, Y
core +1 more source