Results 51 to 60 of about 30,353 (249)

Diversified mcr-1-Harbouring Plasmid Reservoirs Confer Resistance to Colistin in Human Gut Microbiota

mBio, 2016
Colistin is an ultimate line of refuge against multidrug-resistant Gram-negative pathogens. Very recently, the emergence of plasmid-mediated mcr-1 colistin resistance has become a great challenge to global public health, raising the possibility that ...
Huiyan Ye, Yihui Li, Zhencui Li, Rongsui Gao, Han Zhang, Ronghui Wen, George F. Gao, Qinghua Hu, Youjun Feng   +8 more
doaj   +1 more source

Prevalence, genomic characteristics, and transmission dynamics of mcr-1-positive Salmonella enterica Typhimurium from patients with infectious diarrhea

International Journal of Medical Microbiology, 2021
Background: Previous studies reported the prevalence of mcr-1 among clinical infected Salmonella isolates in China. However, the transmission dynamics of mcr-1 in different ecological niches were not well investigated.
Cong Shen, Furong Ma, Suiyan Deng, Lan-Lan Zhong, Mohamed Abd El-Gawad El-Sayed Ahmed, Guili Zhang, Bin Yan, Min Dai, Fan Yang, Yong Xia, Guo-Bao Tian   +10 more
doaj   +1 more source

Mechanically Mutable Matrices: A Hierarchical Investigation of Decellularized Sea Cucumber Collagen as an Adaptable Scaffold Material

Advanced Functional Materials, EarlyView.
Sea cucumber mutable collagenous tissue (MCT) is a remarkable collagen‐based material which can rapidly undergo large changes in stiffness through transiently bound effector proteins. Here, we investigate the hierarchical structure and mechanical response of MCT from Cucumaria frondosa across length scales with a wide range of methods, also exploring ...
Nathalie R. H. Singh, Amy K. Lin, Sabra Rostami, Cameron Hastie, Paul W. Wiseman, Patrick Flammang, Christopher Moraes, Matthew J. Harrington   +7 more
wiley   +1 more source

Prevalence and Characteristic of Swine-Origin mcr-1-Positive Escherichia coli in Northeastern China

Frontiers in Microbiology, 2021
The emergence of the plasmid-mediated colistin resistance gene mcr-1 is threatening the last-line role of colistin in human medicine. With mcr-1-positive Escherichia coli (E.
Ping Cheng, Yuqi Yang, Sai Cao, Haibin Liu, Xiaoting Li, Jichao Sun, Fulei Li, Muhammad Ishfaq, Xiuying Zhang   +8 more
doaj   +1 more source

Increasing Inter‐Micellar Connectivity Toughens and Imparts Cooling‐Induced Shape Memory in Micellar Hydrogels

Advanced Functional Materials, EarlyView.
Oligomerizing Pluronic triblock copolymers provides a processing strategy for tuning the mechanical properties and stimuli‐responsive behaviors of micellar hydrogels. Varying oligomer fraction produces hydrogels spanning brittle to highly extensible responses; maintaining micellar architectures enables cooling‐induced reverse thermal shape memory and ...
Gourav Kumbhojkar, Eric Yang, Arman Moussavi, EunBi Oh, Haeji Kim, Wei Chen, Junsoo Kim, Sinan Keten, Ryan L. Truby   +8 more
wiley   +1 more source

Occurrence and Genomic Characterization of Two MCR-1-Producing Escherichia coli Isolates from the Same Mink Farmer

mSphere, 2019
The spread of colistin resistance gene mcr-1 at the animal-human interface remains largely unknown. This work aimed to investigate the molecular characteristics of two extended-spectrum-β-lactamase (ESBL)-producing Escherichia coli strains with mcr-1, i ...
Beiwen Zheng, Hao Xu, Chen Huang, Xiao Yu, Lihua Guo, Huiming Han, Jing Zhang, Xiawei Jiang, Chunlei Chen, Yonghong Xiao   +9 more
doaj   +1 more source

Genetic Analysis of mcr-1-Carrying Plasmids From Gram-Negative Bacteria in a Dutch Tertiary Care Hospital: Evidence for Intrapatient and Interspecies Transmission Events

Frontiers in Microbiology, 2021
The role of plasmids in the complex pandemic of antimicrobial resistance is increasingly being recognized. In this respect, multiple mobile colistin resistance (mcr) gene-carrying plasmids have been described.
Nikolaos Strepis, Anne F. Voor in ’t holt, Margreet C. Vos, Willemien H. A. Zandijk, Astrid P. Heikema, John P. Hays, Juliëtte A. Severin, Corné H. W. Klaassen   +7 more
doaj   +1 more source

Nanodiamond Sensing in Dynamic Environments With Fast‐Tracking Through Four‐Point Positioning

Advanced Functional Materials, EarlyView.
A four‐point positioning tracking (4PPT) platform enables fast 3D feedback translational tracking of fluorescent nanodiamonds while simultaneously recording ODMR spectra. By integrating real‐time translational tracking with quantum sensing, mobile nanodiamonds are used for in‐situ nanothermometry, nanorheometry, and 6D translation–rotation tracking in ...
Guoli Zhu, Ming‐Zhong Ai, Zhi‐Yu Zhao, Weng‐Hang Leong, Shi‐Ning Chen, Xi Liu, Jing‐Wei Fan, Xi Feng, Ren‐Bao Liu, Yue Cui, Quan Li   +10 more
wiley   +1 more source

The occurrence and molecular detection of mcr-1 and mcr-5 genes in Enterobacteriaceae isolated from poultry and poultry meats in Malaysia

Frontiers in Microbiology, 2023
The advent of antimicrobials-resistant (AMR), including colistin-resistant bacteria, poses a significant challenge to animal and human health, food safety, socio-economic growth, and the global environment.
Md Rezaul Karim, Md Rezaul Karim, Zunita Zakaria, Zunita Zakaria, Latiffah Hassan, Nik Mohd Faiz, Nur Indah Ahmad   +6 more
doaj   +1 more source

A Single Residue within the MCR-1 Protein Confers Anticipatory Resilience

Microbiology Spectrum, 2022
The global presence of transferable mcr genes in a wide range of Gram-negative bacteria from clinical, veterinary, food, and aquaculture environments is disconcerting. Its success as a transmissible resistance factor remains enigmatic, because its expression imposes fitness costs and imparts only moderate levels of ...
Frantz, Renate, Gwozdzinski, Konrad, Gisch, Nicolas, Doijad, Swapnil Prakash, Hudel, Martina, Wille, Maria, Abu Mraheil, Mobarak, Schwudke, Dominik, Imirzalioglu, Can, Falgenhauer, Linda, Ehrmann, Michael, Chakraborty, Trinad, Justus Liebig University Giessen   +12 more
openaire   +6 more sources