Results 31 to 40 of about 30,032,226 (297)

Dissemination and Mechanism for the MCR-1 Colistin Resistance

PLOS Pathogens, 2016
Polymyxins are the last line of defense against lethal infections caused by multidrug resistant Gram-negative pathogens. Very recently, the use of polymyxins has been greatly challenged by the emergence of the plasmid-borne mobile colistin resistance gene (mcr-1).
Rongsui Gao, Yongfei Hu, Zhencui Li, Jian Sun, Qingjing Wang, Jingxia Lin, Huiyan Ye, Fei Liu, Swaminath Srinivas, Defeng Li, Baoli Zhu, Ya-Hong Liu, Guo-Bao Tian, Youjun Feng   +13 more
openaire   +4 more sources

Genetic basis of chromosomally-encoded mcr-1 gene [PDF]

International Journal of Antimicrobial Agents, 2018
Compared with plasmid-borne mcr-1, the occurrence of chromosomally-encoded mcr-1 is rare although it has been reported in several cases. This study aimed to investigate the genetic features of chromosomally-encoded mcr-1 among Escherichia coli strains as well as the potential genetic basis governing mobilisation of mcr-1 in bacterial chromosomes.
Ruichao, Li, Hua, Yu, Miaomiao, Xie, Kaichao, Chen, Ning, Dong, Dachuan, Lin, Edward Wai-Chi, Chan, Sheng, Chen   +7 more
openaire   +5 more sources

Elimination of the risks of colistin resistance gene (mcr-1) in livestock manure during composting

Environment International, 2019
Since its discovery in Escherichia coli, the emergence and rapid spread of the plasmid-mediated colistin resistance gene mcr-1 have become a public health concern.
Yanzheng Gao, Chao Lu, Di Shen, Juan Liu, Zhao Ma, Bing Yang, Wanting Ling, Michael Gatheru Waigi   +7 more
doaj   +1 more source

sj-docx-1-mcr-10.1177_10775587231213691 – Supplemental material for Interruptions in Insurance Coverage and Prescription Drug Utilization: Evidence from Kentucky

, 2023
Supplemental material, sj-docx-1-mcr-10.1177_10775587231213691 for Interruptions in Insurance Coverage and Prescription Drug Utilization: Evidence from Kentucky by Giacomo Meille in Medical Care Research and ...
Giacomo Meille (14058238)
core   +1 more source

Prevalence of mcr-1 in Colonized Inpatients, China, 2011–2019 [PDF]

Emerging Infectious Diseases, 2021
In response to the spread of colistin resistance gene mcr-1, China banned the use of colistin in livestock fodders. We used a time-series analysis of inpatient colonization data from 2011-2019 to accurately reveal the associated fluctuations of mcr-1 that occurred in inpatients in response to the ban.
Cong Shen, Lan-Lan Zhong, Zhijuan Zhong, Yohei Doi, Jianzhong Shen, Yang Wang, Furong Ma, Mohamed Abd El-Gawad El-Sayed Ahmed, Guili Zhang, Yong Xia, Cha Chen, Guo-Bao Tian   +11 more
openaire   +3 more sources

sj-docx-1-mcr-10.1177_10775587231153008 – Supplemental material for Retail Health Clinic Growth as a Potential Primary Care Disruptor

, 2023
Supplemental material, sj-docx-1-mcr-10.1177_10775587231153008 for Retail Health Clinic Growth as a Potential Primary Care Disruptor by Hilary Barnes, Diane Alexander and Michael R.
Diane Alexander (14600965), Michael R. Richards (9643054), Hilary Barnes (7873793)   +2 more
core   +1 more source

Features of the mcr-1 Cassette Related to Colistin Resistance [PDF]

Antimicrobial Agents and Chemotherapy, 2016
The recent description of the plasmid-mediated colistin resistance gene, mcr-1 , in strains isolated from food animals, food and humans in China was a signal for an avalanche of retrospective and prospective studies investigating the occurrence of this specific gene (1).…
Zurfluh, Katrin, Kieffer, Nicolas, Poirel, Laurent, Nordmann, Patrice, Stephan, Roger   +4 more
openaire   +5 more sources

Emergence of mcr-1 and mcr-3 variants coding for plasmid-mediated colistin resistance in Escherichia coli isolates from food- producing animals in South Korea

International Journal of Infectious Diseases, 2018
We hereby report the first characterization of mcr-3 gene from healthy animals in South Korea. Out of 636 E. coli isolates, collected between 2014- 2017, nine colistin resistant isolates were screened for the presence of mcr-1 and mcr-3 genes. Nine (1.4%)
Kuastros Mekonnen Belaynehe, Seung Won Shin, Kyung Yoon Park, Ji Young Jang, Ho Geun Won, In Joong Yoon, Han Sang Yoo   +6 more
doaj   +1 more source

Clinical relevance and plasmid dynamics of mcr-1-positive Escherichia coli in China: a multicentre case-control and molecular epidemiological study

The Lancet Microbe, 2020
Summary: Background: Although the emergence of the plasmid-mediated colistin resistance gene, mcr-1, caused global concern, little is known about its clinical implications and transmission characteristics over time.
Yan Jiang, PhD, Ying Zhang, PhD, Jun Lu, MS, Qihui Wang, MS, Yushan Cui, MS, Yanfei Wang, MS, Jingjing Quan, PhD, Dongdong Zhao, MD, Xiaoxing Du, MS, Haiyang Liu, MS, Xi Li, PhD, Xueqing Wu, PhD, Xiaoting Hua, PhD, Ye Feng, PhD, Yunsong Yu, ProfMD   +14 more
doaj   +1 more source

sj-docx-1-mcr-10.1177_10775587221126777 – Supplemental material for Toward a Uniform Classification of Nurse Practitioner Scope of Practice Laws

, 2022
Supplemental material, sj-docx-1-mcr-10.1177_10775587221126777 for Toward a Uniform Classification of Nurse Practitioner Scope of Practice Laws by Benjamin J.
Sara Markowitz (9667291), Benjamin J. McMichael (13881977)   +1 more
core   +1 more source