Results 31 to 40 of about 36,778 (291)

Escenario actual de la resistencia a la colistina mediada por plásmidos en América Latina [PDF]

, 2019
Colistin resistance can occur by chromosomal mutations and by acquisition of plasmid-carrying determinants, mainly mcr-1. In the recent years, we have observed the outburst of this resistance gene in our region. Due to the risk of the rapid dissemination
Di Conza, José Alejandro, Nastro, Marcela, Quiroga, Cecilia   +2 more
core   +1 more source

Ecology of blaNDM and mcr-1

Journal of Laboratory and Precision Medicine, 2017
Antibiotic resistance is one of the most worrying threats to global public health today. Numerous common infections are becoming harder, and even impossible, to treat due to the loss of effectiveness of these molecules against resistant bacteria.
Jose Francisco Delgado-Blas, Bosco R. Matamoros, Bruno Gonzalez-Zorn   +2 more
openaire   +1 more source

Prevalence of mcr-1 in Colonized Inpatients, China, 2011–2019 [PDF]

Emerging Infectious Diseases, 2021
In response to the spread of colistin resistance gene mcr-1, China banned the use of colistin in livestock fodders. We used a time-series analysis of inpatient colonization data from 2011-2019 to accurately reveal the associated fluctuations of mcr-1 that occurred in inpatients in response to the ban.
Cong Shen, Lan-Lan Zhong, Zhijuan Zhong, Yohei Doi, Jianzhong Shen, Yang Wang, Furong Ma, Mohamed Abd El-Gawad El-Sayed Ahmed, Guili Zhang, Yong Xia, Cha Chen, Guo-Bao Tian   +11 more
openaire   +3 more sources

Genome Sequence of AvianEscherichia coliStrain IHIT25637, an Extraintestinal PathogenicE. coliStrain of ST131 Encoding Colistin Resistance Determinant MCR-1 [PDF]

, 2016
Sequence type 131 (ST131) is one of the predominant Escherichia coli lineages among extraintestinal pathogenic E. coli (ExPEC) that causes a variety of diseases in humans and animals and frequently shows multidrug resistance.
Bauerfeind, Rolf, Bülte, Maria, Ewers, Christa, Fiedler, Sophie, Göttig, Stephan, Heydel, Carsten, Leidner, Ursula, Semmler, Torsten, Tietgen, Manuela   +8 more
core   +2 more sources

Real-time PCR for detection of plasmid-mediated polymyxin resistance (mcr-1) from cultured bacteria and stools [PDF]

, 2016
The aim of the study was to develop a simple assay for rapid detection of the mcr-1 gene, recently identified as a source of plasmid-mediated acquired resistance to polymyxins in Enterobacteriaceae.Methods: A SYBR Green-based real-time PCR assay was ...
Bontron, Séverine, Nordmann, Patrice, Poirel, Laurent   +2 more
core   +1 more source

Elimination of the risks of colistin resistance gene (mcr-1) in livestock manure during composting

Environment International, 2019
Since its discovery in Escherichia coli, the emergence and rapid spread of the plasmid-mediated colistin resistance gene mcr-1 have become a public health concern.
Yanzheng Gao, Chao Lu, Di Shen, Juan Liu, Zhao Ma, Bing Yang, Wanting Ling, Michael Gatheru Waigi   +7 more
doaj   +1 more source

Detection of mcr-1 encoding plasmid-mediated colistin-resistant Escherichia coli isolates from human bloodstream infection and imported chicken meat, Denmark 2015 [PDF]

, 2015
The plasmid-mediated colistin resistance gene, mcr-1, was detected in an Escherichia coli isolate from a Danish patient with bloodstream infection and in five E. coli isolates from imported chicken meat.
Aarestrup, Frank Møller, Agersø, Yvonne, Cavaco, Lina, Hammerum, A. M., Hansen, D. S., Hansen, F., Hasman, H., Hendriksen, Rene S., Kaas, Rolf Sommer, Leekitcharoenphon, Pimlapas, Olesen, B., Skov, R. L., Stegger, M., Zankari, Ea   +13 more
core   +1 more source

Clinical relevance and plasmid dynamics of mcr-1-positive Escherichia coli in China: a multicentre case-control and molecular epidemiological study

The Lancet Microbe, 2020
Summary: Background: Although the emergence of the plasmid-mediated colistin resistance gene, mcr-1, caused global concern, little is known about its clinical implications and transmission characteristics over time.
Yan Jiang, PhD, Ying Zhang, PhD, Jun Lu, MS, Qihui Wang, MS, Yushan Cui, MS, Yanfei Wang, MS, Jingjing Quan, PhD, Dongdong Zhao, MD, Xiaoxing Du, MS, Haiyang Liu, MS, Xi Li, PhD, Xueqing Wu, PhD, Xiaoting Hua, PhD, Ye Feng, PhD, Yunsong Yu, ProfMD   +14 more
doaj   +1 more source

Prevalence, risk factors, outcomes, and molecular epidemiology of mcr-1 -positive Enterobacteriaceae in patients and healthy adults from China: an epidemiological and clinical study [PDF]

, 2017
Background The mcr-1 gene confers transferable colistin resistance. mcr-1-positive Enterobacteriaceae (MCRPE) have attracted substantial medical, media, and political attention; however, so far studies have not addressed their clinical impact. Herein, we
Doi, Yohei, Fang, Ying, Huang, Xi, Lei, Lei, Li, Hong-Yu, Liu, Jian-Hua, Ren, Hongwei, Shen, Jianzhong, Shen, Yingbo, Shen, Zhangqi, Tian, Guo-Bao, Tyrrell, Jonathan M., Walsh, Timothy R., Wang, Shaolin, Wang, Yang, Wu, Congming, Zeng, Kun-Jiao, Zhang, Rong, Zhong, Lan-Lan, Zhou, Hongwei   +19 more
core   +2 more sources

Emergence of mcr-1 and mcr-3 variants coding for plasmid-mediated colistin resistance in Escherichia coli isolates from food- producing animals in South Korea

International Journal of Infectious Diseases, 2018
We hereby report the first characterization of mcr-3 gene from healthy animals in South Korea. Out of 636 E. coli isolates, collected between 2014- 2017, nine colistin resistant isolates were screened for the presence of mcr-1 and mcr-3 genes. Nine (1.4%)
Kuastros Mekonnen Belaynehe, Seung Won Shin, Kyung Yoon Park, Ji Young Jang, Ho Geun Won, In Joong Yoon, Han Sang Yoo   +6 more
doaj   +1 more source