Results 11 to 20 of about 30,032,226 (297)
MCR-1-dependent lipid remodelling compromises the viability of Gram-negative bacteria
Emerging Microbes and Infections, 2022 The global dissemination of the mobilized colistin resistance gene, mcr-1, threatens human health. Recent studies by our group and others have shown that the withdrawal of colistin as a feed additive dramatically reduced the prevalence of mcr-1. Although
Siyuan Feng +15 more
doaj +2 more sources
Molecules, 2022 The emergence of the plasmid-mediated colistin resistance gene mcr-1 has resulted in the loss of available treatments for certain severe infections.
Shengnan Xie +6 more
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Remarkable Diversity of Escherichia coli Carrying mcr-1 from Hospital Sewage with the Identification of Two New mcr-1 Variants [PDF]
Frontiers in Microbiology, 2017 The plasmid-borne colistin-resistant gene mcr-1 has rapidly become a worldwide public health concern. This study aims to determine the host bacterial strains, plasmids, and genetic contexts of mcr-1 in hospital sewage.
Feifei Zhao +9 more
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Dissemination of the mcr-1 colistin resistance gene [PDF]
The Lancet Infectious Diseases, 2016 Plasmid-mediated transferable colistin resistance encoded by the mcr-1 gene was described in Escherichia coli and Klebsiella pneumoniae isolates from pigs and chicken at a prevalence of around 20%, and in clinical isolates from human beings at a prevalence of around 1% in China.1 The prevalence of the mcr-1 gene in Enterobacteriaceae in other countries
Hattie E, Webb +9 more
+33 more sources
High prevalence of the mcr-1 gene in retail chicken meat in the Netherlands in 2015 [PDF]
Antimicrobial Resistance and Infection Control, 2017 Recently, plasmid-mediated colistin resistance was reported in humans, animals and food. We studied the presence of mcr-1 and mcr-2 in Dutch retail chicken meat. The prevalence of mcr-1 was 24,8% (53/214), whereas mcr-2 was not found. The presence of mcr-
Eefje J. A. Schrauwen +5 more
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SciInappropriate antimicrobial use in food animal farming propels antimicrobial resistance (AMR) that affects all health domains. Colistin is a ‘Reserve’ antibiotic for human treatment to be conserved for multidrug-resistant pathogens; however, it is being ...
Mamun Al Asad +9 more
doaj +2 more sources
Catalytic mechanism of the colistin resistance protein MCR-1 [PDF]
Organic & Biomolecular Chemistry, 2020 Elucidation of the catalytic reaction mechanism of MCR-1 enzyme, responsible for the antimicrobial resistance to colistin, using DFT calculations on cluster models.
Reynier Suardíaz +6 more
openaire +6 more sources
Plasmid maps of pACYC-Para-MCR-1 and pACYC-NP-MCR-1.
, 2023 The plasmid for expressing MCR-1 or M6 under the regulation of arabinose promoter was shown as (A), and the one for expressing target proteins under the regulation of MCR-1 native promoter was shown as (B).
Chenchen Zhang (324804) +16 more
core +1 more source
, 2023 Associated paper: Regulatory fine-tuning and horizontal gene transfer stabilize mobile colistin resistance Lois Ogunlana, Liam P. Shaw, Divjot Kaur, Pramod Jangir, Timothy Walsh, Stephan Uphoff, and R.C. MacLean. Preprint version: https://doi.org/10.
Liam Shaw (5487083)
core +1 more source
Identification of Functional Interactome of Colistin Resistance Protein MCR-1 in Escherichia coli
Frontiers in Microbiology, 2021 The emergence and worldwide dissemination of plasmid-mediated colistin resistance gene mcr-1 has attracted global attention. The MCR-1 enzyme mediated colistin resistance by catalyzing phosphoethanolamine (PEA) transfer onto bacterial lipid A.
Hui Li +7 more
doaj +1 more source