Results 21 to 30 of about 37,498,974 (256)

Molecular detection of colistin resistance genes (mcr-1, mcr-2 and mcr-3) in nasal/oropharyngeal and anal/cloacal swabs from pigs and poultry [PDF]

Scientific Reports, 2018
Antimicrobial resistance against colistin has emerged worldwide and is threatening the efficacy of colistin treatment of multi-resistant Gram-negative bacteria. In this study, PCRs were used to detect mcr genes (mcr-1, mcr-2, mcr-3) in 213 anal and 1,339
Jilei Zhang, Li Chen, Jiawei Wang, Afrah Kamal Yassin, Patrick Butaye, Patrick Kelly, Jiansen Gong, Weina Guo, Jing Li, Min Li, Feng Yang, Zhixing Feng, Ping Jiang, Chunlian Song, Yaoyao Wang, Jinfeng You, Yi Yang, Stuart Price, Kezong Qi, Yuan Kang, Chengming Wang   +20 more
doaj   +3 more sources

Emergence of mcr-1 and mcr-3 variants coding for plasmid-mediated colistin resistance in Escherichia coli isolates from food- producing animals in South Korea

International Journal of Infectious Diseases, 2018
We hereby report the first characterization of mcr-3 gene from healthy animals in South Korea. Out of 636 E. coli isolates, collected between 2014- 2017, nine colistin resistant isolates were screened for the presence of mcr-1 and mcr-3 genes. Nine (1.4%)
Kuastros Mekonnen Belaynehe, Seung Won Shin, Kyung Yoon Park, Ji Young Jang, Ho Geun Won, In Joong Yoon, Han Sang Yoo   +6 more
doaj   +3 more sources

Colistin Resistance Mediated by Mcr-3-Related Phosphoethanolamine Transferase Genes in Aeromonas Species Isolated from Aquatic Environments in Avaga and Pakro Communities in the Eastern Region of Ghana [PDF]

Infection and Drug Resistance
Samiratu Mahazu,1,2 Isaac Prah,1,3 Yusuke Ota,1 Takaya Hayashi,3 Masato Suzuki,4 Mitsunori Yoshida,5 Yoshihiko Hoshino,5 Yukihiro Akeda,6 Toshihiko Suzuki,7 Tomoko Ishino,2 Anthony Samuel Ablordey,8 Ryoichi Saito1 1Department of Molecular Microbiology ...
Mahazu S, Prah I, Ota Y, Hayashi T, Suzuki M, Yoshida M, Hoshino Y, Akeda Y, Suzuki T, Ishino T, Ablordey AS, Saito R   +11 more
doaj   +3 more sources

Molecular Insights into Functional Differences between mcr-3- and mcr-1-Mediated Colistin Resistance [PDF]

Antimicrobial Agents and Chemotherapy, 2018
The global emergence of plasmid-mediated colistin resistance genes mcr-1 and mcr-3 has threatened the role of the “last-resort” drug colistin in the defense against infections caused by multidrug-resistant Gram-negative bacteria.
Hui Li, Lu Yang, Zhihai Liu, Wenjuan Yin, Dejun Liu, Ying-Bo Shen, T. Walsh, Bing Shao, Yang Wang   +8 more
semanticscholar   +5 more sources

Multiplex PCR for detection of plasmid-mediated colistin resistance determinants, mcr-1, mcr-2, mcr-3, mcr-4 and mcr-5 for surveillance purposes [PDF]

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2018
Background and aim Plasmid-mediated colistin resistance mechanisms have been identified worldwide in the past years. A multiplex polymerase chain reaction (PCR) protocol for detection of all currently known transferable colistin resistance genes (mcr-1 ...
A. R. Rebelo, V. Bortolaia, J. Kjeldgaard, S. Pedersen, P. Leekitcharoenphon, I. M. Hansen, B. Guerra, B. Malorny, M. Borowiak, J. Hammerl, A. Battisti, A. Franco, Patricia Alba, A. Perrin-Guyomard, S. Granier, Cristina De Frutos Escobar, S. Malhotra-Kumar, L. Villa, A. Carattoli, R. Hendriksen   +19 more
semanticscholar   +4 more sources

Multidrug Resistance and Virulence Factors of Escherichia coli Harboring Plasmid-Mediated Colistin Resistance: mcr-1 and mcr-3 Genes in Contracted Pig Farms in Thailand. [PDF]

Front Vet Sci, 2020
The presence of the plasmid-mediated colistin resistance encoding mcr gene family in the Enterobacteriaceae is one of the crucial global concerns. The use of colistin in livestock rearing is believed to be the cause of mcr gene spreading and is of impact
Khine NO, Lugsomya K, Kaewgun B, Honhanrob L, Pairojrit P, Jermprasert S, Prapasarakul N.   +6 more
europepmc   +2 more sources

The Co-occurrence of mcr-3 and fosA3 in IncP plasmid in ST131 Escherichia coli: A novel case.

The Journal of Infection in Developing Countries, 2022
INTRODUCTION Plasmid-mediated colistin resistance genes, especially mcr-3 combined with the fosfomycin resistance gene fosA3, are a grave health concern.
Muhammad Fazal Hameed, Yanan Chen, Hazrat Bilal, Sabir Khan, H. Ge, Xiaofang Chen, Pengying Gu   +6 more
semanticscholar   +4 more sources

Plasmid- and chromosome-located mcr-3 in mcr-1-positive Escherichia coli in Taiwan

International Journal of Antimicrobial Agents, 2020
[[abstract]]The mobile colistin resistance gene, mcr-1, and its variants have been detected among humans and domestic animals worldwide. Since its first detection in 2017, mcr-3 has been reported in Asia, Europe and North America.
Hsu, CY;Chen, FJ;Huang, WC;Liao, YC;Lauderdale, TL;Kuo, SC
core   +3 more sources

Molecular detection of colistin resistance genes (mcr-1 to mcr-5) in human vaginal swabs

BMC Research Notes, 2018
Objective Colistin resistance has emerged worldwide and has been threatening the efficacy of one of the last-resort antimicrobials used for treatment of multidrug resistant Gram-negative bacteria. While five colistin resistance genes (mcr-1, mcr-2, mcr-3,
Jilei Zhang, Li Chen, Jiawei Wang, Patrick Butaye, Ke Huang, Haixiang Qiu, Xiaomei Zhang, Weijuan Gong, Chengming Wang   +8 more
doaj   +2 more sources

Characterization of NMCR-3, NMCR-4 and NMCR-5, three novel non-mobile colistin resistance determinants: Implications for MCR-3, MCR-7, and MCR-5 progenitors, respectively

Drug Resistance Updates
In this study, the progenitors of MCR-3, MCR-7 and MCR-5, namely NMCR-3, NMCR-4 and NMCR-5, were firstly discovered and indicating Aeromonas was a natural reservoir for MCR-3 and MCR-7.
Weicheng Bei, Huanchun Chen, Anusak Kerdsin   +2 more
exaly   +2 more sources