Results 101 to 110 of about 72,878,926 (153)

Genomic characterization and stability of mcr-carrying plasmids in Klebsiella pneumoniae from Taiwanese hospitals: Identification of a distinct mcr-9-harboring plasmid in the high-risk ST11-KL47 clone

Journal of Infection and Public Health
Background: The spread of colistin-resistant Klebsiella pneumoniae carrying mobilized colistin resistance (mcr) genes via plasmids threatens last-line treatment options and complicates infection control in healthcare settings.
Yi-Jiun Pan, Tuyet-Anh Nguyen Thi, Nai-Wen Tsao, Tran Lam Tu Quyen, Yi-Yin Chen, Yu-Jung Chen, Jo-Ping Chang, Shiao-Wen Li, Chong-Wei Huang, Yu-Chia Hsieh   +9 more
doaj   +1 more source

Genomic characterization of multidrug-resistant Enterobacter asburiae clinical isolates co-harboring mcr-9 and blaIMP-8

Journal of Global Antimicrobial Resistance
Carbapenem-non-susceptible Enterobacter cloacae complex (ECC) strains represent an emerging clinical challenge in Taiwan. This study characterized the genomic context of plasmid-mediated multidrug-resistance genes, particularly the co-occurrence of blaIMP-8 and mcr-9, in ECC isolates.Three carbapenem-non-susceptible ECC isolates (YGH005, YGH008, and ...
Moan-Shane Tsai, Tzu-Ling Yang
openaire   +2 more sources

Acquired mutations in transcriptional regulator hns and lipopolysaccharide biosynthesis and modification genes impact colistin resistance and fitness of mcr-carrying E. coli

Antimicrobial Agents and Chemotherapy
Gram-negative bacteria can develop resistance to the last-resort antimicrobial colistin through the acquisition of mobile colistin resistance (mcr) genes or chromosomal mutations.
Anna Schumann, Ian P. O’Keefe, Robert K. Ernst, Martin Wiedmann   +3 more
doaj   +1 more source

Functional domain analysis of MCR protein.

, 2013
(A) SDS-PAGE of purified MCR, MCR-N, and MCR-C proteins. (B) In vitro analysis of malonyl-CoA reductase activity. Enzyme activities were assayed as described in Materials and Methods.
Yamei Ding (461417), Guang Zhao (324536), Changshui Liu (461416), Qi Wang (22418), Mo Xian (186207)   +4 more
core   +1 more source

Prevalence and characteristics of mcr-9-positive Salmonella isolated from retail food in China

LWT, 2022
Huanjing Sheng, Jiaqi Ma, Qiuping Yang, Wei Li, Qian Zhang, Chengqian Feng, Jin Chen, Mingqian Qin, Xiumin Su, Puyao Wang, Jie Zhang, Wei Zhou, Linna Zhao, Li Bai, Shenghui Cui, Baowei Yang   +15 more
openaire   +1 more source

High Prevalence of Colistin-Resistant Encoding Genes Carriage among Patients and Healthy Residents in Vietnam

Medicina
Background and Objectives: We aimed to investigate the carriage of colistin-resistant genes among both patients with a history of antibiotic exposure and apparently healthy adults with no recent healthcare contact. Materials and Methods: Stool swabs were
Viet Ha Le, Thi Diep Khong, Ngoc Quang Phan, Thi Hoa Tran, Hong Ngoc Vu, Dong Van Quyen, Van Thuan Hoang, Nam Thang Nguyen   +7 more
doaj   +1 more source

Rapid multiplex polymerase chain reaction for detection of mcr-1 to mcr-5 genes [PDF]

, 2019
A rapid (total time 
Lescata, Mathilde, Nordmann, Patrice, Poirel, Laurent   +2 more
core  

Site-selective modifications by lipid A phosphoethanolamine transferases linked to colistin resistance and bacterial fitness

mSphere
Genes encoding lipid A modifying phosphoethanolamine transferases (PETs) are genetically diverse and can confer resistance to colistin and antimicrobial peptides.
Anna Schumann, Ahmed Gaballa, Hyojik Yang, Di Yu, Robert K. Ernst, Martin Wiedmann   +5 more
doaj   +1 more source

Plasmid-encoded lactose metabolism and mobilized colistin resistance (<i>mcr-9</i>) genes in <i>Salmonella enterica</i> serovars isolated from dairy facilities in the 1980s. [PDF]

Microb Genom, 2023
Kröger C, Lerminiaux NA, Ershova AS, MacKenzie KD, Kirzinger MW, Märtlbauer E, Perry BJ, Cameron ADS, Schauer K.   +8 more
europepmc   +1 more source

Insertion sequences in mgrB and mutations in two-component system genes confer high polymyxin resistance to carbapenem-resistant Enterobacter cloacae complex strains

Frontiers in Microbiology
Due to the complexity of identifying the Enterobacter cloacae complex (ECC) at the species level, little is known about the distribution of carbapenem-resistant ECC (CRECC).
Jiming Wu, Jisheng Zhang, Jianmin Wang, Jin Wang, Xushan Liang, Chunli Wei, Wenzhang Long, Yang Yang, Yuhui Chen, Mingjing Liao, Youtao Liang, Kaixin Yu, Xiaoli Zhang   +12 more
doaj   +1 more source