Results 31 to 40 of about 26,451 (216)

mcr-9, an Inducible Gene Encoding an Acquired Phosphoethanolamine Transferase in Escherichia coli, and Its Origin. [PDF]

Antimicrob Agents Chemother, 2019
The plasmid-located mcr-9 gene, encoding a putative phosphoethanolamine transferase, was identified in a colistin-resistant human fecal Escherichia coli strain belonging to a very rare phylogroup, the D-ST69-O15:H6 clone.
Kieffer N, Royer G, Decousser JW, Bourrel AS, Palmieri M, Ortiz De La Rosa JM, Jacquier H, Denamur E, Nordmann P, Poirel L.   +9 more
europepmc   +7 more sources

Screening for mobile colistin resistance gene-9 (mcr-9) in multidrug resistant uropathogenic Escherichia coli isolated from patients with urinary tract infections [PDF]

BMC Research Notes
Objective Colistin and Polymyxin B form the reserve group of antibiotics. Resistance to colistin has been increasing across the world including India, posing treatment challenges to clinicians.
Divya Lakshmanan, K. Vanathy, Catherine Thamayandhi, Sreejith Sreekumaran, E. K. Radhakrishnan, S. Srirangaraj   +5 more
doaj   +2 more sources

Co-Occurrence of mcr-9 and blaNDM-1 in Enterobacter cloacae Isolated from a Patient with Bloodstream Infection

Infection and Drug Resistance, 2020
Minmin Lin,1,* Yongqiang Yang,2– 4,* Yanxian Yang,2,3,* Guanping Chen,5 Ruowen He,2,3 Yiping Wu,2,3 Lan-Lan Zhong,2,3 Mohamed Abd El-Gawad El-Sayed Ahmed,2,3,6 Siyuan Feng,2,3 Cong Shen,2,3 Xin Wen,2,3 Jin Huang,1 Hongyu Li,7 Xiaobin Zheng,1 Guo ...
Lin M, Yang Y, Yang Y, Chen G, He R, Wu Y, Zhong LL, El-Sayed Ahmed MAEG, Feng S, Shen C, Wen X, Huang J, Li H, Zheng X, Tian GB   +14 more
doaj   +4 more sources

Coproduction Of MCR-9 And NDM-1 By Colistin-Resistant Enterobacter hormaechei Isolated From Bloodstream Infection. [PDF]

Infect Drug Resist, 2019
Colistin acts as the last line of defense against severe infections caused by carbapenem-resistant Enterobacteriaceae. Infections caused by extensively drug-resistant isolates coproducing MCR and carbapenemases have posed a serious public health concern.In this study, we reported the first clinical colistin and carbapenem-resistant Enterobacter ...
Yuan Y, Li Y, Wang G, Li C, Xiang L, She J, Yang Y, Zhong F, Zhang L.   +8 more
europepmc   +5 more sources

Transcriptomic analysis of induced resistance to polymyxin in carbapenem-resistant Enterobacter cloacae complex isolate carrying mcr-9

Journal of Global Antimicrobial Resistance
: Objectives: Polymyxins are currently the last-resort treatment against multi-drug resistant Gram-negative bacterial infections, but plasmid-mediated mobile polymyxin resistance genes (mcr) threaten its efficacy, especially in carbapenem-resistant ...
Jiming Wu, Longjin Liu, Jianmin Wang, Ying Wang, Xinhui Li, Xiaoyu Wang, Shan Jiang, Wengang Li, Jisheng Zhang, Xiaoli Zhang   +9 more
doaj   +3 more sources

One Health Analysis of mcr-Carrying Plasmids and Emergence of mcr-10.1 in Three Species of Klebsiella Recovered from Humans in China

Microbiology Spectrum, 2022
The global dissemination of the mobile colistin resistance (mcr) gene illustrates how the use of colistin in veterinary medicine can affect human health, exemplifying the concept of One Health.
Melissa Chunjiao Liu, Zijuan Jian, Wenen Liu, Junhua Li, Na Pei   +4 more
doaj   +1 more source

Emergence of IncHI2 Plasmids With Mobilized Colistin Resistance (mcr)-9 Gene in ESBL-Producing, Multidrug-Resistant Salmonella Typhimurium and Its Monophasic Variant ST34 From Food-Producing Animals in Italy

Frontiers in Microbiology, 2021
A collection of 177 genomes of Salmonella Typhimurium and its monophasic variant isolated in 2014–2019 from Italian poultry/livestock (n = 165) and foodstuff (n = 12), previously screened for antimicrobial susceptibility and assigned to ST34 and single ...
Elena Lavinia Diaconu, Patricia Alba, Fabiola Feltrin, Paola Di Matteo, Manuela Iurescia, Eleonora Chelli, Valentina Donati, Ilaria Marani, Angelo Giacomi, Alessia Franco, Virginia Carfora   +10 more
doaj   +1 more source

Epidemiology of mobile colistin resistance genes mcr-1 to mcr-9

Journal of Antimicrobial Chemotherapy, 2020
Abstract The identification of the first mobile colistin resistance (MCR) gene, mcr-1, in 2015 triggered a rash of mcr screening reports. Subsequently, nine MCR-family genes and their variants have been described. However, a comprehensive overview concerning the epidemiology of the whole MCR family, which is essential for facilitating ...
Zhuoren, Ling, Wenjuan, Yin, Zhangqi, Shen, Yang, Wang, Jianzhong, Shen, Timothy R, Walsh   +5 more
openaire   +2 more sources

Detection and genomic characterization of mcr-9 in Enterobacter hormaechei recovered from a pediatric patient in Lebanon

Infection, Genetics and Evolution, 2021
The emergence and spread of mobilized colistin resistance (mcr) genes are a global health concern.In this study, we report the detection and genomic characterization of mcr-9 in a colistin-susceptible Enterobacter hormaechei (EH23) recovered from a pediatric patient in Lebanon.EH23 was susceptible to colistin with a minimal inhibitory concentration ...
Ragheed, Khodor, Tamara, Salloum, Tamima, El Jisr, Mira, El Chaar, Sima, Tokajian   +4 more
openaire   +2 more sources

Molecular characterization of NDM-1-producing carbapenem-resistant E. cloacae complex from a tertiary hospital in Chongqing, China

Frontiers in Cellular and Infection Microbiology, 2022
BackgroundThe aim of this study was to clarify the molecular characterization of NDM-1-producing carbapenem-resistant Enterobacter cloacae complex (CREL) at a teaching hospital in Chongqing, China.MethodsAntimicrobial susceptibility and resistance genes ...
Kewang Hu, Kewang Hu, Jisheng Zhang, Jingbo Zou, Lingyi Zeng, Lingyi Zeng, Jie Li, Jianmin Wang, Wenzhang Long, Xiaoli Zhang   +9 more
doaj   +1 more source