Results 31 to 40 of about 25,588 (94)

Identification of Novel Mobilized Colistin Resistance Gene mcr-9 in a Multidrug-Resistant, Colistin-Susceptible Salmonella enterica Serotype Typhimurium Isolate

mBio, 2019
Mobilized colistin resistance (mcr) genes are plasmid-borne genes that confer resistance to colistin, an antibiotic used to treat severe bacterial infections. To date, eight known mcr homologues have been described (mcr-1 to -8). Here, we describe mcr-9,
Laura M. Carroll, Ahmed Gaballa, Claudia Guldimann, Genevieve Sullivan, Lory O. Henderson, Martin Wiedmann   +5 more
doaj   +1 more source

Co-occurrence of blaNDM-1, rmtC, and mcr-9 in multidrug-resistant Enterobacter kobei strain isolated from an infant with urinary tract infection

Journal of Global Antimicrobial Resistance, 2023
: Objectives: The co-emergence of mcr and carbapenem resistance genes in Gram-negative bacteria is a serious problem. This study aims to clarify the genetic characteristic of one novel multidrug-resistant Enterobacter kobei EC1382 with mcr-9 causing ...
Haiyan Zeng, Yujing Tan, Jianhui Su, Fei Gao, Tao Lei, Bingshao Liang   +5 more
doaj   +1 more source

Large-scale genomic survey and characterization of mcr genes carried by foodborne Cronobacter isolates

mSystems, 2023
Antibiotic resistance has become a worldwide public health and biosafety problem. The clinical efficacy of colistin was jeopardized by the report of the first mobile colistin resistance (mcr) gene, and subsequently, the mcr-gene family of mcr-1 to mcr-10
Qianhui Zhu, Jinrui Hu, Na Liu, Heyuan Qi, Xiaoli Du, Zhigang Cui, Yan Sun, Yadong Liu, Songnian Hu, Linhuan Wu, Haijian Zhou, Zilong He, Juncai Ma   +12 more
doaj   +1 more source

First Genomic Characterization of bla_VIM-1 and mcr-9-Coharbouring Enterobacter hormaechei Isolated from Food of Animal Origin

Pathogens, 2020
We describe here the complete genome sequence of an Enterobacter hormaechei ST279 coharbouring blaVIM-1 and mcr-9 recovered from uncooked beef patty in June 2017, Egypt.
Mustafa Sadek, Hirofumi Nariya, Toshi Shimamoto, Shizuo Kayama, Liansheng Yu, Junzo Hisatsune, Motoyuki Sugai, Patrice Nordmann, Laurent Poirel, Tadashi Shimamoto   +9 more
doaj   +1 more source

Emergence of a Multidrug-Resistant Enterobacter hormaechei Clinical Isolate from Egypt Co-Harboring mcr-9 and bla_VIM-4

Microorganisms, 2020
This study describes the first full genomic sequence of an mcr-9 and blaVIM-4-carrying multidrug-resistant Enterobacter hormaechei clinical isolate from Egypt. The strain was isolated in April 2015 from the sputum of a patient in Cairo, Egypt.
Ahmed M. Soliman, Fumito Maruyama, Hoda O. Zarad, Atsushi Ota, Hirofumi Nariya, Toshi Shimamoto, Tadashi Shimamoto   +6 more
doaj   +1 more source

Plasmid-mediated colistin resistance among human clinical Enterobacterales isolates: national surveillance in the Czech Republic

Frontiers in Microbiology, 2023
The occurrence of colistin resistance has increased rapidly among Enterobacterales around the world. We performed a national survey of plasmid-mediated colistin resistance in human clinical isolates through a retrospective analysis of samples from 2009 ...
Marketa Zelendova, Marketa Zelendova, Costas C. Papagiannitsis, Petra Sismova, Petra Sismova, Matej Medvecky, Matej Medvecky, Katarina Pomorska, Jana Palkovicova, Jana Palkovicova, Kristina Nesporova, Vladislav Jakubu, Vladislav Jakubu, Ivana Jamborova, Helena Zemlickova, Helena Zemlickova, Monika Dolejska, Monika Dolejska, Monika Dolejska, Monika Dolejska, Working Group for Monitoring of Antibiotic Resistance   +20 more
doaj   +1 more source

Co-occurrence of blaNDM–1 and mcr-9 in a Conjugative IncHI2/HI2A Plasmid From a Bloodstream Infection-Causing Carbapenem-Resistant Klebsiella pneumoniae

Frontiers in Microbiology, 2021
Spread of the carbapenemase-encoding and mobilized colistin resistance (mcr) genes among Enterobacteriales poses a great threat to global public health, especially when the both genes are transferred by a single plasmid.
Zhou Liu, Xiubing Hang, Xiao Xiao, Wenwen Chu, Xin Li, Yangyang Liu, Yangyang Liu, Yangyang Liu, Xi Li, Qiang Zhou, Jiabin Li, Jiabin Li, Jiabin Li, Jiabin Li   +13 more
doaj   +1 more source

Epidemiological and genomic characteristics of global mcr-positive Escherichia coli isolates

Frontiers in Microbiology, 2023
ObjectiveThe worldwide dissemination of colistin-resistant Escherichia coli (E. coli) endangers public health. This study aimed to better understand the global genomic epidemiology of E.
Jiping Shi, Hong Zhu, Chang Liu, Hui Xie, Chuchu Li, Xiaoli Cao, Han Shen   +6 more
doaj   +1 more source

mcr-1 Identified in Fecal Escherichia coli and Avian Pathogenic E. coli (APEC) From Brazil

Frontiers in Microbiology, 2021
Colisitin-associated resistance in bacteria of food producing animals has gained significant attention with the mcr gene being linked with resistance. Recently, newer variants of mcr have emerged with more than nine variants currently recognized. Reports
Nicolle Lima Barbieri, Ramon Loureiro Pimenta, Dayanne Araujo de Melo, Lisa K. Nolan, Miliane Moreira Soares de Souza, Catherine M. Logue   +5 more
doaj   +1 more source

Different methionine to cysteine supplementation ratios altered bone quality of broilers with or without Eimeria challenge assessed by dual energy X-ray absorptiometry and microtomography

Poultry Science
: Despite the acknowledged significance of nutrition in bone development, effects of methionine (Met) and cysteine (Cys) on bone quality remain under-researched, particularly during Eimeria challenge. We investigated the effects of different supplemental
Guanchen Liu, Milan K. Sharma, Yuguo H. Tompkins, Po-Yun Teng, Woo K. Kim   +4 more
doaj   +1 more source