Phenotypic and genotypic characterization of colistin-resistant Escherichia Coli with mcr-4, mcr-5, mcr-6, and mcr-9 genes from broiler chicken and farm environment. [PDF]
Background Colistin is an antibiotic used as a last-resort to treat multidrug-resistant Gram-negative bacterial infections. Colistin had been used for a long time in veterinary medicine for disease control and as a growth promoter in food-producing ...
Lemlem M +9 more
europepmc +2 more sources
Complete Genome Sequence of Hafnia paralvei Isolate AVS0177, Harboring mcr-9 on a Plasmid. [PDF]
Here, we report the complete genome sequence of a Hafnia paralvei strain isolated from a lake in Switzerland in 2020. The genome consists of a 4.7-Mbp chromosome, a large plasmid (213 kb) harboring mcr-9 , and a small plasmid (6 kb).
Biggel M +6 more
europepmc +4 more sources
Objective: Polymyxins are last-resort antibiotics for multidrug-resistant Gram-negative bacterial infections, but their efficacy is threatened by plasmid-mediated colistin resistance genes ( mcr ).
Lingxian Yi +5 more
doaj +3 more sources
Minmin Lin,1,* Yongqiang Yang,2– 4,* Yanxian Yang,2,3,* Guanping Chen,5 Ruowen He,2,3 Yiping Wu,2,3 Lan-Lan Zhong,2,3 Mohamed Abd El-Gawad El-Sayed Ahmed,2,3,6 Siyuan Feng,2,3 Cong Shen,2,3 Xin Wen,2,3 Jin Huang,1 Hongyu Li,7 Xiaobin Zheng,1 Guo ...
Lin M +14 more
doaj +4 more sources
Yi Yuan,1,* Ying Li,2,* Guangxi Wang,3 Chengwen Li,2 Li Xiang,3 Junping She,3 Yan Yang,3 Fangcai Zhong,1 Luhua Zhang3 1Department of Clinical Laboratory, The First People’s Hospital of Neijiang, Sichuan, People’s Republic of China ...
Yuan Y +8 more
doaj +4 more sources
Epidemiological and genomic characteristics of global mcr-positive Escherichia coli isolates [PDF]
ObjectiveThe worldwide dissemination of colistin-resistant Escherichia coli (E. coli) endangers public health. This study aimed to better understand the global genomic epidemiology of E.
Jiping Shi +6 more
doaj +2 more sources
MCR-3 and MCR-9 confer species-specific increases in colistin MICs. [PDF]
For the clinical treatment of infections with Enterobacteriaceae , the development of resistance to last-resort antimicrobials like colistin is of concern, as it limits treatment options. Since 2015, ten families of mobile colistin resistance (
Schumann A, Wiedmann M.
europepmc +3 more sources
Dissemination of a IncHI2A plasmid co-harboring the mcr-9 and bla<sub>NDM-1</sub> genes in Israeli hospitals. [PDF]
The mcr-9 allele is typically located on IncHI2 type plasmids, but there are only few reports describing the co-occurrence of the blaNDM gene on the same plasmid. Our aims were to describe the spread of an IncHI2A plasmid harboring both the mcr-9 and the blaNDM-1 genes in a multicenter study in Israel.
Adler A +4 more
europepmc +3 more sources
Complete Genome Sequence of an mcr-9-Possessing Enterobacter asburiae Strain Isolated from a Cat in Japan. [PDF]
We report the complete genome sequence of the mcr-9 -possessing strain Enterobacter asburiae En30, isolated from a cat in Japan. The genome sequence was obtained by using long- and short-read sequencing.
Sato T +6 more
europepmc +3 more sources
Exploring the Global Spread of Klebsiella grimontii Isolates Possessing blaVIM-1 and mcr-9. [PDF]
The spread of plasmid-mediated carbapenemases within Klebsiella oxytoca is well-documented. In contrast, data concerning the closely related species Klebsiella grimontii are scarce.
Campos-Madueno EI +4 more
europepmc +4 more sources

