Potential spread of mcr-9-carrying IncHI2 plasmids in Enterobacter hormaechei in Vietnam
Journal of Global Antimicrobial Resistance, 2021 : Objectives: Mobile colistin resistance (mcr) genes are widely distributed around the world. To date, ten major variants of mcr genes are known (mcr-1 to mcr-10).
Van Thi Thu Ha +7 more
doaj +3 more sources
Phenotypic and genotypic characterization of colistin-resistant Escherichia Coli with mcr-4, mcr-5, mcr-6, and mcr-9 genes from broiler chicken and farm environment. [PDF]
BMC Microbiol, 2023 Background Colistin is an antibiotic used as a last-resort to treat multidrug-resistant Gram-negative bacterial infections. Colistin had been used for a long time in veterinary medicine for disease control and as a growth promoter in food-producing ...
Lemlem M +9 more
europepmc +2 more sources
Molecular antibiotic resistance mechanisms and co-transmission of the mcr-9 and metallo-β-lactamase genes in carbapenem-resistant Enterobacter cloacae complex [PDF]
Frontiers in Microbiology, 2022 Carbapenem-resistant Enterobacter cloacae complex (CRECC) has increasingly emerged as a major cause of healthcare-associated infections, with colistin being one of the last-resort antibiotics of treatment.
Shan Jiang +15 more
doaj +2 more sources
MCR-3 and MCR-9 confer species-specific increases in colistin MICs. [PDF]
Microbiology (Reading)For the clinical treatment of infections with Enterobacteriaceae , the development of resistance to last-resort antimicrobials like colistin is of concern, as it limits treatment options. Since
Schumann A, Wiedmann M.
europepmc +2 more sources
Conjugative IncHI2/HI2A plasmids harbouring mcr-9 in colistin-susceptible Escherichia coli isolated from diseased pigs in Japan. [PDF]
Access Microbiol, 2022 journal articleColistin is a last resort antimicrobial used for the treatment of gram-negative bacterial infections. Plasmid-mediated colistin resistance (mcr) genes are a cause of global concern, and, thus far, mcr-1–10 have been identified.
Fukuda A +4 more
europepmc +2 more sources
First Detection of mcr-9 in a Multidrug-Resistant Escherichia coli of Animal Origin in Italy Is Not Related to Colistin Usage on a Pig Farm [PDF]
Antibiotics, 2023 The emergence of colistin resistance raises growing concerns because of its use as a last-resort antimicrobial for the treatment of severe gram-negative bacterial infections in humans. Plasmid-borne mobile colistin resistance genes (mcr) are particularly
Flavia Guarneri +10 more
doaj +2 more sources
Identification of novel mobile colistin resistance gene mcr-10
Emerging Microbes and Infections, 2020 Mobile colistin resistance (mcr) genes represent an emerging challenge. Here we describe a novel mcr gene, mcr-10, on an IncFIA plasmid of an Enterobacter roggenkampii clinical strain.
Yu Feng, Yu Feng, Mei Kang
exaly +3 more sources
Identification of Novel Mobilized Colistin Resistance Gene
mBio, 2019 Mobilized colistin resistance (mcr) genes are plasmid-borne genes that confer resistance to colistin, an antibiotic used to treat severe bacterial infections. To date, eight known mcr homologues have been described (mcr-1 to -8). Here, we describe mcr-9,
Laura M. Carroll +5 more
doaj +2 more sources
Microbiology Spectrum, 2022 The global dissemination of the mobile colistin resistance (mcr) gene illustrates how the use of colistin in veterinary medicine can affect human health, exemplifying the concept of One Health.
Melissa Chunjiao Liu +4 more
doaj +2 more sources
Emergence of concurrently transmissible mcr-9 and carbapenemase genes in bloodborne colistin-resistant Enterobacter cloacae complex isolated from ICU patients in Kolkata, India [PDF]
Microbiology SpectrumColistin resistance in carbapenem-resistant Enterobacter cloacae complex (CR-ECC) infections has grown expeditiously but detecting the underlying mechanism of resistance is often challenging in clinical settings. This study, first of its kind from India,
Gourab Halder +5 more
doaj +2 more sources